Associate Professor & CPRIT scholar @MDAndersonNews studying stress responses in tumor microenvironment and anti-tumor immunity.
Joined September 2020
- Tweets 57
- Following 345
- Followers 362
- Likes 582
Photos and videos
20 Nov 2024
Many congratulations to @LV_Xiangdong who has been awarded the CPRIT scholar award to set up his own lab at @UTHealthHouston! He is amazing!
20 Nov 2024
BREAKING NEWS: #CPRIT approved $89 million in grants to advance the state’s fight against cancer, including CPRIT Scholar recruitment awards, evidence-based prevention programs and innovative companies developing new cancer drugs and treatments.
READ: ow.ly/m9Qg50Ub8qi
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20 Oct 2024
Thank you @theNAMedicine @MDAndersonNews and all who contribute to our mission to #endcancer - patients and families, care teams, researchers and supporters worldwide. Honored to continue this important work together
8 Oct 2024
Jennifer A. Wargo (@jenwargomd) of @MDAndersonNews was elected as a member of the National Academy of Medicine in 2023. Congratulations and welcome! #NAMclassof2023
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16 Oct 2024
Happy to share our latest work showing that an ancient ER-localized RNase IRE1 coordinates with p53 to silence taxane-induced dsRNA and protect immune-cold TNBC from pore-forming pyroptosis. @CellCellPress @MDAndersonNews cell.com/cell/abstract/S0092…
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16 Oct 2024
Kudos to the amazing trainees @LongyongX @FanglueP and all fantastic collaborators!
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16 Oct 2024
Inhibiting IRE1 RNase in TP53-mutant TNBC allows taxane to be highly immunogenic, triggering dsRNA-ZBP1-NLRP3-GSDMD pyroptotic signaling cascade, turning PD-L1-negative cold tumors hot, and conferring these cold tumors hypersensitivity to PD-1 inhibitor.
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3 May 2024
Here are 10 things to know about our Dr. Jim Allison, who was recently elected to the 2024 National Inventors Hall of Fame. @JimAllisonPhD @InventorsHOF #EndCancer
3 May 2024
#NIHF2024 Inductee @JimAllisonPhD has a deep appreciation for endeavors that enrich life. His love of music has led him to play in a blues band composed of @sitcancer members & immunologists or oncologists, called The Checkpoints. @MDAndersonNews bit.ly/44nkB72
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15 Apr 2024
The Allison Institute will be hosting a Next Gen Colloquium in Houston ahead of SITC in November. Details in photo. Please sign up or contact me with any questions.
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21 Sep 2023
Recruiting faculty to the Dept of Molecular and Cellular Biology at Baylor College of Medicine in Houston! Recruiting broadly in cancer and cell biology. Apply by Nov 1, 2023. @BCMhouston
nature.com/naturecareers/job…
bcm.edu/departments/molecula…
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19 Sep 2023
Wonderful session on #UPR and #ISR. Learned a lot from the amazing talks from @ACKoongMDPhD @Eric_Chevet @apoptosislab !
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7 Sep 2023
Happy to share our latest work in collaboration with @HaoqiangY published in @ScienceMagazine today: Proteostasis network reprogramming is a key convergence point of multiple KRAS inhibitor resistance mechanisms.
science.org/doi/10.1126/scie…
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7 Sep 2023
Kudos to @LV_Xiangdong @XuanLu11447800 and all authors for the fantastic teamwork. Thanks @NCICancerBio for supporting this work.
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9 Jul 2021
Happy to share our latest work with Stanley Adoro on identifying #ERAD as a critical protein quality control checkpoint for T cell development. @eLife @bcmhouston doi.org/10.7554/eLife.69975
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5 Feb 2021
FEATURED Review in this month's issue: JR Cubillos-Ruiz @JCubRuiz & X Chen @XiChenLab discuss how #ERstress can influence pro-tumoural features of cancer cells & reprogram the function of #immunecells, creating targetable vulnerabilities. go.nature.com/2UKRrMo
@NatResCancer
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19 Nov 2020
Excited to share our review with @JCubRuiz on ER stress in cancer @NatureRevCancer under the wonderful guidance of @annaedart ! @bcmhouston
nature.com/articles/s41568-0…
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19 Nov 2020
Thank you @Eric_Chevet @costas_koumenis and the anonymous reviewer for the insightful comments!
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6 Oct 2020
Join us @bcmhouston. Fantastic department with incredible environment and support to start your lab!
5 Oct 2020
Recruiting faculty @bcmhouston! Multiple assistant prof positions in the MCB dept AND the Stem Cell Cntr! Looking for expertise in #epigenetics #generegulation #cellbio #synbio #organoids #stemcells…
bit.ly/2HyoOhY
bit.ly/363q46V
Why consider BCM? Read on.
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22 Sep 2020
Thank you @Goodell_Lab ! So fortunate to be in the amazing MCB department @bcmhouston with enormous support from Peggy and incredible colleagues!
22 Sep 2020
Please give a warm Twitter welcome to @XiChenLab who just joined. -Fantastic faculty member in MCB department @bcmhouston. Beautiful new @NatureCellBio paper on protein QC in #HSCs! Congrats!
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21 Sep 2020
Thank you @SignerLab for writing a wonderful and insightful News & Views highlighting our paper @NatureCellBio ! We love the title "ERADicating stem cells from their niche"!
21 Sep 2020
ERADicating stem cells from their niche. Our News & Views on exquisite new work from @XiChenLab in @NatureCellBio on how proteostasis regulation by the ERAD pathway influences the interaction of HSCs with their perivascular niche in the bone marrow. rdcu.be/b7vFR
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21 Sep 2020
Very pleased to share our latest work on ER-Associated Degradation (#ERAD) as a critical protein quality checkpoint that controls HSC-niche interaction and determines the fate of HSCs. @NatureCellBio @bcmhouston
nature.com/articles/s41556-0…
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