Professor of Cell Biology and Physiology at Washington University in St. Louis. Research interests: genotoxic stress, innate immune response, RNA surveillance

Joined April 2019
7 Photos and videos
Congratulations to Abby Cheruiyot, a former graduate student in the lab, on receiving the K99/R00 award!
K99/R00 awarded! Thank you @NIDDKgov. I’m so grateful for the support of my mentors Drs Schaffer and Bonner-Weir and other supporters @JoslinDiabetes, PhD mentor @YouLab_WashU and others at @MEDA_WashU , @HMSBPA @LeadingEdgeSymp @natblackpostdoc
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Excited to share our latest finding: TCAF1, an ion channel regulator, has a novel role in fork protection during replication stress! Huge congrats to Lingzhen, Chen and Shan and all co-authors! Big thanks to @DavePistonWUSTL @BMajorLab @NimaMLab for their incredible support!
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This is our third paper on the cytosolic DNA/Ca2 -dependent signaling pathway we identified, crucial for protecting stalled replication forks. TCAF1 facilitates the activation of the pathway by promoting the dissociation between STING and TRPV2 and subsequent ER Ca2 release.
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Zhongsheng You, PhD retweeted
Excited to share (with my 8 followers) graduate student Ernst Schmid’s “SPOC” classifier, which can pick a good AlphaFold-Multimer prediction out of a crowd, and predictomes.org/, a database of PPIs in the genome maintenance space. biorxiv.org/content/10.1101/…
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Zhongsheng You, PhD retweeted
Thank you to @SitemanCenter, @WashUOnc, @WashUHeme, @wusm_pathology, @WUSTLPeds, and @SLUbiochem for supporting our 3rd Annual @GenomeIntegrity Retreat! A very successful event with a great group of people
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Zhongsheng You, PhD retweeted
Was an honor to host Johannes Walter for our @GenomeIntegrity seminar! Mind-blown by his terrific talk @VindigniLab @YouLab_WashU John Krais @WUSTLdbbs @WUSTLmed @SitemanCenter
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Zhongsheng You, PhD retweeted
I am honored to have the platform to share my work and incredibly grateful to have received an award!! Thank you to my mentors Matt Walter and @YouLab_WashU. Thank you @ASH_hematology #ASH2023 @WUSTLdbbs @WashUOnc
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Exciting days at the MCB/CBP retreat! Outstanding presentations and stimulating discussions highlighting cutting-edge research from various labs. A big cheer for our new graduate students whose enthusiasm and inquisitive spirits are truly energising @WUSTLCellBio @WUSTLdbbs
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A very nice article about Claudia Cabrera @ccpastrana21, a truly inspiring graduate student, and her accomplishments. We are lucky to be part of her graduate school @WUSTLdbbs @WUDeptMedicine @WUSTLCellBio internalmedicine.wustl.edu/c…
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Big congratulations to @ccpastrana21 on receiving the NIH F31 predoctoral fellowship for her work on NMD and cancer treatment! Well done Claudia! 👏👏👏@WUSTLdbbs @WUSTLCellBio @WUDeptMedicine
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Zhongsheng You, PhD retweeted
Congratulations to our @MEDA_WashU Trainee Chair Claudia Cabrera @ccpastrana21 for her amazing talk at the #HDMP2023 @WashUOnc @SitemanCenter Retreat! @WUSTLdbbs @wustl_sacnas @IDEASDOM_WUSM
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Great to be back to the Salk Institute to see my scientific heroes, celebrate their lives and achievements, and learn great science!
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Great presentation! Congratulations, Lingzhen!
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Zhongsheng You, PhD retweeted
Great presentations from trainees and our keynote speaker Matt Weitzman at the 2023 CGI Retreat!
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Zhongsheng You, PhD retweeted
Lab sharing gang @DjuranovicLab @WUSTLCellBio @YouLab_WashU
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MCB recent graduate Lucia Capano and MCB student Max Lyon moderating the Careers in Science: Industry and & Entrepreneurship and Careers in Science: Academia discussion sessions, respectively, at the @WUSTLdbbs 50th anniversary celebration(@WUSTLCellBio). Great job Lucia and Max!
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Congratulations to @AbbyCheru on being selected as a Leading Edge Fellow! Abby was also an HHMI International Student Research Fellow as a graduate student at Washington University @WUSTLCellBio @WUSTLdbbs
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Thanks Shan for the invitation! Looking forward to the webinar!
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Thank Dr. Iestyn Whitehouse, for a great talk. Dr. You @YouLab_WashU from Washington University will tell us about the how replication fork response to the Ca signals. Sign up at cancer.columbia.edu/research…
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Zhongsheng You, PhD retweeted
#MEDAHighlight We are excited to introduce a new Trainee Committee Chair Claudia Cabrera Pastrana @MEDA_WashU @ccpastrana21. @ccpastrana21 is a @WUSTLdbbs @WashUOnc PhD student & a #diversity leader. She studies #myelodysplasticsyndromes. #DiversityandInclusion #mentorship
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