@UMNChemistry Ph.D. candidate in @DanHarki group. Forever screening small molecules and playing around with the random number generator (aka mass spec!).

Joined August 2019
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This synthesis might be incredibly frustrating, but at least I get a pretty looking column out of it! #RealTimeChem
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Very excited to have this paper from my time in grad school published! Started from an unrelated project idea that lead to weird results. Working on #APOBEC3A? Your catalytic inactivation mutation may lead to unstable protein! Check out the paper below to learn why E72A > E72Q.
14 Feb 2023
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If you’re at #ACSFall2022 and you love drug discovery, come see me present my poster on our virtual and in vitro screening project for APOBEC3B inhibitors!
24 Aug 2022
Wednesday presentations by #HarkiLab members at #ACSChicago2022. Check out the work by ⁦@_ChemKat⁩ and Michael Grillo to develop ligands targeting APOBEC3B DNA cytosine deaminase. ⁦@AcsMedi@UMNChemistry⁩ ⁦@UMN_MedChem⁩.
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Katherine Jones retweeted
20 Jul 2022
PAPER OUT !! 🎉🥂🍾 @nature nature.com/articles/s41586-0… Viral restrictor APOBEC3A is a major cause of mutational signatures found in >50% of cancers more, Tweetorial👇 With @J_Maciejowski Via WGS/251 cancer clones (available!) @broadinstitute @MSKCancerCenter @sangerinstitute
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Honored to have received this fellowship alongside these other amazing chemists!
Congrats to PhD students Margaret Clapham, Brianna Collins, Mckenna Hanson, Hannah Holst, and Katherine Jones for receiving highly competitive #UMN Doctoral Dissertation Fellowships! z.umn.edu/ChemDDF2022 #UMNproud @UMNCSE
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If you’re looking for a postdoc position in medicinal chemistry or chemical biology, come join our lab! #chempostdoc
18 Apr 2022
I am looking to fill at least 3 postdoctoral positions in the #HarkiLab @UMN_MedChem. Check out the team and projects at harki.umn.edu.
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Exciting new research from @jtang162 that I was happy to be a part of is finally out in the world! Folks at #AACR22, go to his talk this afternoon!
11 Apr 2022
New lab #preprint! HLB-0532259: A chemical degrader of N-Myc that targets Aurora kinase A. Want to hear the development story in-person? @jtang162 from the #HarkiLab will present at #AACR22 today - 3:05 pm, New Orleans Theater B. @UMN_MedChem @UMNCancer biorxiv.org/content/10.1101/…
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Our review (@DanHarki @HarrisLabUMN) on the current toolbox for APOBEC3 drug discovery is online now at @TrendsinPharma! So happy to see my first review paper finally out in the world! cell.com/trends/pharmacologi…

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Katherine Jones retweeted
11 Feb 2022
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A COVID Saturday night means board games feat Polyoply, the polymer version of Monopoly feat @UMNChemistry professors
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Also a reminder for any grad student being paid by a not pre-taxed fellowship like the NSF GRFP!
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Lab Dan is ready for the best time of the year — baseball season! @DanHarki
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Katherine Jones retweeted
Small Molecule of the Year, 2020: drughunter.com/2020smotygs/ The drug discovery community voted on their favorite molecule from 2020, and their 2020 pick is GS-6207, @GileadSciences awe-inspiring HIV capsid inhibitor. Full story at drughunter.com. #chemtwitter #biotwitter
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Katherine Jones retweeted
24 Feb 2021
The 2021 version of the #HarkiLab! Not pictured: Deborah Rodriguez and Anand Divakaran. @UMN_MedChem @UMNChemistry @UMNCancer
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Thanks, Dan! A big shout out goes to our whole lab, who helped me prepare and gave me awesome feedback for the presentation! @jtang162 @KTPhos @SamanthaKennel3 @adivkrn
7 Dec 2020
Congrats to #HarkiLab grad student Katherine Jones @_ChemKat for receiving a best presentation award! #TeamAPOBEC @UMNChemistry @UMNCancer cse.umn.edu/chem/news/studen…
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A great paper to work on, in which we developed a new type of ALARM assay using mass spec peptide sequencing to identify binding of reversible covalent compounds! Check it out!
18 Nov 2020
A new publication from our collaboration with @KayBrummond's lab is now online. Synthetic guaianolides with tunable electrophiles! pubs.acs.org/doi/10.1021/acs…
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Katherine Jones retweeted
The president-elect's #covid19 task force is stacked with some of the best healthcare minds in America, including @Atul_Gawande @mtosterholm @RickABright @ZekeEmanuel @celinegounder @vivek_murthy statnews.com/2020/11/09/bide…
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Exciting news this Saturday morning: a third paper from my post-bac research position was published in FSI: Genetics! Does differential hair growth across the scalp affect protein polymorphism profiles within an individual? Check it out! authors.elsevier.com/c/1bwR5…

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Amazing visualizations from @RommieAmaro's lab! Got see her present these images at a recent #TeamAPOBEC meeting. Their modeling of the glycan shield and discovery of a potential structural role was particularly fascinating. Check out their pub in @ACSCentSci if you get a chance.
Here are detailed images of the coronavirus that are helping scientists better understand and fight it. nyti.ms/3dbLEI9
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