Professor Molecular Genetics, PI at Hubrecht Institute and Princess Máxima Center, Utrecht NL. Director of Institute of Human Biology of pRED, Roche, Basel CH
Joined June 2013
- Tweets 544
- Following 211
- Followers 18,099
- Likes 321
Photos and videos
May 10
A short write-up about the journey of our lab. Starting as T cell immunologists, we stumbled across Wnt signaling in flies and frogs. Worked on colon cancer. Then Nick Barker (left) discovered the gut stem cell and Toshi Sato invented organoids authors.elsevier.com/a/1n3No…
ALT (Photo from lab retreat ~2012)
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Hans Clevers retweeted
🎙️ We have a new episode out!
We chat with Drs. Shuibing Chen (@ChenShuibing) and Hans Clevers (@HansClevers) from the #ISSCR Consortium on Advanced Stem Cell-Based Models in Drug Discovery and Development
They discuss how stem cell–derived organoids and other new approach methodologies (#NAMs) can complement or replace animal models in preclinical research.
🔊 Listen now: bit.ly/46sLQQe
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Hans Clevers retweeted
Feb 21
Must-read Review in Nature Medicine from @DanielJDrucker: a masterclass on how GLP-1 medicines moved from glucose control to reshaping obesity, CV, liver, kidney, neuro and addiction care.
nature.com/articles/s41591-0…
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The future of faster drug discovery may be on the horizon. #Organoids, tiny simplified versions of human tissues, help us test potential medicines in faster, more predictive ways.
A new review with @Hubrecht Institute explores how.
👏 Thank you to the scientists driving this work.
Read more 👉 spkl.io/6017Ai1dt
#DrugDiscovery #Innovation #pRED @IHB_Research @Hans Clevers
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11 Dec 2025
Daisong Wang and Sangho Lim describe human gut organoids with Peyer's patch M cells. M cells not only transport antigens: like professional antigen-presenting cells, they process and present gluten (the celiac disease antigen) directly to T cells rdcu.be/eT5s7
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Single-chain TS2/16 integrin β1-activating antibody as a soluble supplement
up to 10-fold ⏫ yields of 2D/3D Visceral (small intestine, colon, stomach, pancreas/liver) Organoids🤠
What would be its impacts on blood vessel organoids & assembloids?😆
@HansClevers @TheCleversLab @NatureBiotech 2025
nature.com/articles/s41587-0…
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Hans Clevers retweeted
31 Oct 2025
Explore the gala highlights and see the most memorable moments, featuring remarks by Prof. @HansClevers and jury president Prof. @SilviaPriori1.
⬇️
abarcaprize.com/award-ceremo…
#AbarcaPrize2025 #MedicalResearch #MedicalAward #Organoids
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Hans Clevers retweeted
25 Oct 2025
Great opportunity to join a fantastic lab at @IHB_Research !
25 Oct 2025
We are searching for computational PhDs and Postdocs to join our group in collaboration with @TreutleinLab . We have exciting single-cell technology projects that incorporate bioengineering, computation, biology, translation. Send CV to deco_ihb@roche.com
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22 Oct 2025
Polyisocyanide (PIC) hydrogel with the essential properties of #Matrigel. Functionalised with the integrin activating Yersinia protein #Invasin for #organoid growth. Joost Wijnakker et al. Great collaboration with Paul Kouwer's lab. PMID: 41091766
hubrecht.eu/bacteria-to-the-…
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1 Oct 2025
Honored to receive the #AbarcaPrize2025. Not surprisingly, I'm very passionate about #organoids and their immense potential to transform how we approach drug discovery and development. @AbarcaPrize
Honored to see @HansClevers recognized Abarca Prize in Spain! A remarkable achievement that demonstrates how science and compassion go hand in hand. Find out more about here:spkl.io/6013ApTSd
#AbarcaPrize #ResearchPrize #EarlyDevelopment #MedicalResearch
ALT Roche Abarca Prize Hans Clevers
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18 Sep 2025
For the #organoid research group that I founded at the Princess Máxima Center, we are looking for a motivated postdoc with experience in gene editing and bioinformatics. Contact Karin Sanders (k.sanders@prinsesmaximacentrum.nl) to learn more. @prinsesmaximac
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6 Sep 2025
1/11 In @ScienceMagazine: A new perspective on how our intestines renew. Cells are not “pushed out” by crowding or die from apoptosis. Instead, cells play a mechanical tug-of-war, where weaker cells extrude, reframing gut renewal as force-regulated. science.org/doi/10.1126/scie…
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6 Sep 2025
11/11 Take-home: Gut homeostasis is not passive crowd control. It’s an active, force-regulated process. Cells constantly test each other’s strength; those that fail the tug-of-war extrude. A collaboration between the @_Hubrecht, @_amolf & @IHB_Research lead by @DanielKruegerDK
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5 Sep 2025
4/4 This work was a true team effort between @_amolf, @ihb_research, and the @_Hubrecht — led by @DanielKruegerDK and Kasper Spoelstra. Huge thanks to all collaborators for making it possible.
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