Firstgen in Yale Center for Infection & Immunity using imaging technologies to study pain in long COVID and similar syndromes. bakermind.bsky.social
Joined October 2012
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A new study co-led by Yale scientists reveals that antibodies from some long COVID patients attacked brain and nerve tissues, a finding that could point toward treatments.
news.yale.edu/2026/05/28/yal…
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I'm excited to share my first full research article as coauthor with @keylas3 @VirusesImmunity et al @YaleCII, on autoantibodies from long COVID patients being sufficient to elicit pathology and symptoms upon transfer to mice (link free til July 17) 1/
sciencedirect.com/science/ar…
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It's pleasure and privilege to work with such a team of talented individuals crossing many disciplines to seek solutions to a looming and underappreciated problem of chronic disease after infection. I can't do a better tweetorial than our leader, so: x.com/i/status/2060017675280…
Excited to share our study by @keylas3 et al. on pathological autoantibodies in people with Long COVID. We asked whether IgG in patients with Long COVID bind to human tissues/antigens and cause pathologies when transferred into mice. With @PutrinoLab
doi.org/10.1016/j.cell.2026.…
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Christopher A. Baker retweeted
Excited to share our study by @keylas3 et al. on pathological autoantibodies in people with Long COVID. We asked whether IgG in patients with Long COVID bind to human tissues/antigens and cause pathologies when transferred into mice. With @PutrinoLab
doi.org/10.1016/j.cell.2026.…
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For people co planning about the WHO guidance on PPE for contact tracers: THIS is what HCWs and contact tracers face in central Africa. The sight of PPE will get people to hide from tracers at best, and set them on fire at worst.
Second Ebola treatment center set on fire in epicenter of disease's outbreak cbsn.ws/4f0MsBD
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"via Kennedy and Laura Loomer" isn't the own you think it is. No data on testing of the employee or the timeline of these "incidents" either. Plus I thought the whole ebola thing was a hoax to undermine the government anyway
May 24
BREAKING: An Ebola-infected monkey recently bit an NIH lab researcher at Rocky Mountain Laboratories in Montana and then was allowed on a plane without being quarantined, according to HHS Secretary Kennedy, per Laura Loomer.
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Christopher A. Baker retweeted
Is there an association between human herpesviruses (HHVs) reactivation and Long COVID? We analyzed HHV DNA shedding in saliva and found that HHV-6 correlates with Long COVID severity. Claire Laxton, @S_Tabachnikova, Lily Cooke, Kexin Wang et al.
medrxiv.org/content/10.64898… (1/)
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Christopher A. Baker retweeted
May 20
Today in @Nature, we report MouseMapper: foundation-model AI to map disease perturbations across the entire mouse body cell-by-cell.
In obesity, it revealed body-wide inflammation & unexpected facial nerve damage. 🧵👇🔉
nature.com/articles/s41586-0… led by @Dorie00 & @yingchen733
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This is standard for the medical field nowadays, especially in Connecticut. Patients die just because there is insufficient (or inadequate) staff. Try to avoid going to a hospital if at all possible
courant.com/2026/05/19/repor…
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In early 2020 I wasn't even working on COVID, but hearing about my wife's patients gave me a strong suspicion that it was going to produce a wave of ME/CFS-like consequences. Some people didn't have a quick recovery, and the vascular components hinted at widespread damage
May 17
Don’t ever let anyone in public health tell you there was no way to know Long COVID would come.
People with pre-COVID ME predicted this from the earliest days of the pandemic. But it was business as usual ignoring the existed of PAIS as medicine/govt had done for decades prior.
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Christopher A. Baker retweeted
In fact, many critics of "let er rip" DID anticipate the scale & impact of #LongCOVID.
Google Scholar notes many studies already in 2020. We drafted the scenario planning (policy calculus) figure in 2020 for a COVlD grant that built the organizational footing for PMC.
ALT Google Scholar: 21,700 search results in 2020 alone.
ALT A figure first drafted in 2020 describing potential pandemic scenarios, each describing possible implications related to Long COVlD
May 17
Reminder: Long COVID's disability & suffering will be the pandemic's most devastating long-term global legacy. Neither GBD supporters nor critics anticipated its scale or included it in their policy calculus -and “let er rip” strategies prioritizing widespread exposure clearly worsen the toll. Millions affected, with real costs in lives and productivity (on top of 20 million direct deaths globally, which we should never forget or minimize). nature.com/articles/s43856-0…
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I remember this very disappointing scenario in which ME/CFS was linked to XMRV infection, only to learn it was a red herring at best and a hoax at worst. Later I discovered the author has gone on to have quite the career in conspiracy theory science.org/doi/10.1126/scie…
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Christopher A. Baker retweeted
May 17
A major theme of PolyBio’s 2026 Spring Symposium: developing and validating Long COVID biomarkers to enable smarter clinical trials, stratified by patient subtype. Here are 6 key presenters that will discuss a promising biomarker platform on May 22. From novel platforms like extracellular vesicles & BARA, to microfluidics capture of persistent SARS-CoV-2, there’s a large body of new IACI research to explore.
Full symposium schedule (Friday May 22, 11 am-5 pm ET / 3-9 pm UTC): polybio.org/2026-spring-symp…
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He thought we were done with infectious disease, but infectious disease wasn't done with us
May 16
This aged well! I guess infectious disease didn’t agree to take a break…
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Christopher A. Baker retweeted
May 14
hallucinated references will land you a 1-year ban from arxiv now. wow
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Christopher A. Baker retweeted
Excited to announce our results from the first ever survey on GLP-1s for Long COVID and ME!
Patient outcomes showed two extremes: while 53% improved, 28% experienced worsening, some long after their last dose.
Full analysis here and in the tweets below:
lcmedata.org/treatments/glp1…
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So many layers of wrong here
May 14
Academia is cruel because it selects for people obsessively interested in a narrow topic, but what’s actually rewarded is the ability to pivot fluidly to whatever’s new and fundable.
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Christopher A. Baker retweeted
May 10
This website visualizes social media as a room with 100 people in it
3 people are producing most of the toxic content
Most people assume 43 are producing toxic content, because these 3 are hyperactive
Engagement-based ranking amplifies the 3 provocative, high-reaction users.
The other 97 quiet voices disappear or self-censor.
And the loud minority thinks it's the majority: the more someone posts, the more they believe the public agrees with them!
thenoisyroom.com/
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OMG the chewy mouse
May 11
Our latest paper is out in @NatureNeuro! Cheese3D🧀 enables sensitive, quantitative analysis of whole-face dynamics in mice.
Manuscript: nature.com/articles/s41593-0…
Code: github.com/Hou-Lab-CSHL/chee…
Led by Kyle Daruwalla & Irene Nozal Martin, with contributions from the entire lab.
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