Bioengineering grad student at BU, BioBuilder educator, @OlinCollege alum. Synthetic biology, human-centered design, & fermented foods. He/him.
Joined March 2016
- Tweets 333
- Following 829
- Followers 407
- Likes 6,262
29 Photos and videos
Pinned Tweet
11 Jun 2022
This was an exciting project, and I am so glad we get to share it now!
11 Jun 2022
Antibiotic resistance genes have been a core tool in synthetic biology since the start. In our new preprint by @biotaxis, we develop tools that will enable control over bacterial survival in space and time using light. 🦠💡
biorxiv.org/content/10.1101/…
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Michael Sheets retweeted
16 Jun 2023
An excellent contribution to the literature on SynBio education - congrats to the team @EngBioRC !
Introduction to Engineering Biology: A Conceptual Framework for Teaching Synthetic Biology | ACS Synthetic Biology pubs.acs.org/doi/10.1021/acs…
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Michael Sheets retweeted
Minipreps! They're a fact of life. But if they don't bring you joy, you might want to try new tactics or treat yourself to some fun new toys!
Our lab has done 2,625 minipreps so far. Let me share a few tidbits about our approach and our favorite pieces of equipment. 🧵 (1/n)
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Michael Sheets retweeted
27 Mar 2023
On Thursday we had the pleasure of hosting the Tyngsboro High School's BioBuilderClub Team at our Learning Lab! While here, they performed a bacterial transformation with the DNA plasmid they designed. Great work from these amazing students! #tpsprepares #biobuilder
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Michael Sheets retweeted
25 Feb 2023
Our latest paper is out! Light-inducible expression of antibiotic resistance genes. Led by @biotaxis, with help from @NathanTague2. Constructs are on @Addgene if you want to try them out.
24 Feb 2023
And to wrap up today's paperfest, @biotaxis and co in the @DunlopLab at @BostonU_BME present an optogenetic toolkit for light induced antibiotic resistance
go.nature.com/41AGRJd
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24 Feb 2023
Excited to share my latest work! We use light to turn on antibiotic resistance, and can use this to boost fatty acid bioproduction.
24 Feb 2023
And to wrap up today's paperfest, @biotaxis and co in the @DunlopLab at @BostonU_BME present an optogenetic toolkit for light induced antibiotic resistance
go.nature.com/41AGRJd
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Michael Sheets retweeted
1 Feb 2023
Delighted to share our latest paper on the RENDR platform — an engineered ribozyme that can convert RNA signals into orthogonal protein outputs. Published in @NatureComms and led by @laurgamb, @AOStaubus, @Kimwai_Mo, and @andrea_faint. Supported by @NSF
nature.com/articles/s41467-0…
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Michael Sheets retweeted
3 Jan 2023
We are now accepting applications for the 2023 Apprentice Challenge Class! BioBuilder's 8 Week program for Boston area high schoolers that prepares students for summer internships at area academic labs and life science companies.
biobuilder.org/program/high-…
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Michael Sheets retweeted
8 Dec 2022
Interested in bacterial peptide sensing? Check out my latest paper! Thanks to all of my amazing co-authors in
@LabTabor lab beyond: @synthetic_queer Andrew Mu @KGroszman @KyVanHoang @kevin_lorch @bhpogostin @DrGunn43 @jeffrey_j_tabor nature.com/articles/s41589-0…
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Join the EBRC SPA December 6 for Data and Engineering: Operating at the Technical Interface. Panelists will discuss transitioning to industry, their current role, and valuable data-specific skills. Learn more and register here: ebrc.org/ebrc-spa-presents-d…
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Michael Sheets retweeted
3 Nov 2022
Super excited that our paper with @ajofranklinlab, i.e., CAF, is out (doi.org/10.1038/s41586-022-0…) with @meeeeechigan, @su2lin_SEU, Xu Zhang, and George Bennett. Congrats to all!!!
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Michael Sheets retweeted
1 Nov 2022
Very excited to share our new preprint where we use a deep learning-based feedback algorithm to control gene expression in real time in thousands of single E. coli cells in parallel. This work was led by @jblugagne and @cblassick. 1/
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17 Oct 2022
I learned so much through making these slides, and I hope they'll help you learn (and teach) too! Very excited to share a new course module that covers the theory, core tools, and impacts of engineering/synthetic biology: ebrc.org/ed-module-introduct…
Looking to teach #engineeringbiology in your course? EBRC is excited to announce a new resource! Our modular slide deck on the impacts and principles of Engineering Biology, by Michael Sheets @biotaxis and Josh Atkinson @meeeeechigan: ebrc.org/ed-module-introduct…
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Michael Sheets retweeted
14 Oct 2022
Here's our new article -- potentially, everything you ever wanted to know about light-regulated gene expression in bacteria (& much more).
frontiersin.org/articles/10.…
Welcome opportunity to team up once again with @RobertOhlendorf (this guy knows stuff!). Enjoy
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Michael Sheets retweeted
10 Oct 2022
What if you could image 🔬cells and then choose which ones to sequence 🧬?
What if you could go back and image 🔬cells that you previously sequenced 🧬?
Now you can 🔬 then 🧬 then 🔬 cells again with Light-Seq!
nature.com/articles/s41592-0…
Let’s dig in 🧵.
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Michael Sheets retweeted
6 Sep 2022
Genome sequencing of the evolved populations revealed why resistance accelerated in MS but not in SS: mildly-selected resistance mutations were stably maintained without selection, contrarily to strongly-selected mutants that were unstable in drug-free environments.
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Michael Sheets retweeted
18 Aug 2022
REVIEW: Deep Learning Concepts and Applications for Synthetic Biology
@DunlopLab and colleagues present an overview of #SynBio relevant classes of data and #DeepLearning architectures and discuss the challenges and future opportunities in this space.
liebertpub.com/doi/10.1089/g…
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Michael Sheets retweeted
7 Jul 2022
I am pleased to release the @EngBioRC “Synthetic Biology and Machine Learning” education module. In it I talk with synbio/ML researchers about projects in their groups and ideas for how to learn more about this space.
ebrc.org/synbio-ml-education…
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BREAKING: The Supreme Court just reversed nearly 50 years of precedent and overturned Roe v. Wade, ending the federal constitutional right to abortion.
We won't deny what a horrible moment this is.
Half of the states are expected to ban abortion.
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Michael Sheets retweeted
15 Jun 2022
What an amazing meeting #bostonbacterial22 has been! We would like to thank, our 2022 co-chairs @ssespinozam and @Jenna_Wurster, the organizing committee, and all of our attendees for creating a wonderful & engaging environment for science! THANK YOU!
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