The Ho Lab @ColumbiaMed @Columbia_MI - using cryoEM to explore how membrane protein complexes mediate host-pathogen interactions in malaria parasites!

Joined August 2019
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The Ho Lab retweeted
So incredibly excited and grateful to be joining the Burroughs Wellcome Fund PATH family! Thank you @BWFUND and the selection committee members for supporting and believing in our vision, and congrats to the other 2026 PATH Investigators!!! 🥳
May 19
BWF Announces the 2026 Investigators in the Pathogenesis of Infectious Disease bwfund.org/news/bwf-announce… #bwfpath
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The Ho Lab retweeted
Happy to share our new review of kainate receptor structure and gating. @shantigangwar @MariaKarela3 @LauraYen42 frontiersin.org/journals/pha…
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The Ho Lab retweeted
20 Oct 2025
Learn how our hunt for the native structure of top #antimalarial target PfATP4🧂led to the discovery of PfABP, an unknown essential binding partner, out now! @natcomms 👉 rdcu.be/eLRlH 🦠🔬❄️ A team effort by @mehsehret @cmholab & Anurag Shukla @AkhilVaidya1 #cryoEM
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The Ho Lab retweeted
New online! Dynamic TOM–TIM23 supercomplex directs mitochondrial protein translocation and sorting bit.ly/4n7AJC4
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The Ho Lab retweeted
Structures of kainate receptor channel GluK2 in the apo closed and open conducting states, both with 2-fold symmetrical LBD layer. To open the channel, we used agonist kainate and positive allosteric modulator BPAM but no Concanavalin A! @shantigangwar nature.com/articles/s41594-0…
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The Ho Lab retweeted
18 Aug 2025
Our #CryoET story on how a top antimalarial drug candidate perturbs the native malarial translation machinery is out @NatureSMB🥳rdcu.be/eBbrH Massive team effort led by @leonie_anton @mehsehret @Wenjing_Cheng_ in collaboration with @DziekanJerzy @CowmanAlan #teamtomo
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The Ho Lab retweeted
2 Apr 2025
Thank you so much @hypothesisfund and @Yeh_Lab for supporting us in this new venture!! We're excited to get started! 🦠🔬❄️
Replying to @Hypothesisfund
3/ Awardee @mimi1inh tackles the complex challenges of protein sequencing by leveraging molecular machinery made by microbes. Her work could revolutionize how we study protein function structure, & our understanding of biology🤯. 🥳Congrats Dr. Ho! @Columbia 🙏#HFScout @Yeh_Lab
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The Ho Lab retweeted
3/ Awardee @mimi1inh tackles the complex challenges of protein sequencing by leveraging molecular machinery made by microbes. Her work could revolutionize how we study protein function structure, & our understanding of biology🤯. 🥳Congrats Dr. Ho! @Columbia 🙏#HFScout @Yeh_Lab
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The Ho Lab retweeted
🌠 We're thrilled to announce our latest @HypothesisFund awardees and their groundbreaking projects! From optimizing enzymes, to protein sequencing, and membrane 'functional hotspots', each of these projects holds the potential to be broadly transformative for science! 1/ 🧵
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The Ho Lab retweeted
Vertebrate retrotransposons are the future of gene therapy. But how do they insert their genes? 🔥🔥 Thrilled to present part 2 of my postdoctoral work with @NogalesLab @CollinsRNPLab @berkeleyMCB where we investigate this using #CryoEM and transgene insertion in 🧪 and cells!
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The Ho Lab retweeted
14 Nov 2024
The human mitochondrial ClpXP is uniquely assembled and regulated compared to its bacterial counterparts. Congrats to Kelly Chen on her years of hard work on this challenging complex! biorxiv.org/content/10.1101/…
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The Ho Lab retweeted
18 Jun 2024
We have a fully-funded postdoc position in the @cmholab in #NYC to study how #membraneproteins drive host-pathogen interactions in #malaria parasites using #CryoEM and #CryoET!🦠❄️🔬Email chi-min.ho@columbia.edu with your CV to apply! tinyurl.com/5n96rkfm #teamtomo
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The Ho Lab retweeted
We're back! Together with #MPM/#KMCB, we are holding a Young Investigators in Parasitology Meeting (YIPs) for junior PIs! We'll have panels & group discussions on all things to do with starting a new lab. Register here!👇👉tinyurl.com/mr22ahrm
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The Ho Lab retweeted
We'll also have an AMA Panel of #newPIs in #Parasitology who recently started their labs for Postdocs interested in transitioning to independence or going on the job market soon!!! #Postdocs_in_Parasitology come ask us anything at 3PM on Sep 15 in Clapp Auditorium @WoodsHole!
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The Ho Lab retweeted
22 Sep 2023
Manuel Fierro from the Beck Lab and Am @WDedkhad from the @MuralidharanLab closing out #MPM2023 with a bang!! 💪
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