Computational structural biology -- (glycobiology & immunology) | Space 🌌 | Outdoors & dog enthusiast. He/him

Joined February 2020
27 Photos and videos
Daniel Mattox retweeted
Excited to unveil Boltz-2, our new model capable not only of predicting structures but also binding affinities! Boltz-2 is the first AI model to approach the performance of FEP simulations while being more than 1000x faster! All open-sourced under MIT license! A thread… 🤗🚀
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Daniel Mattox retweeted
Statement WWWWWWWin!!
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Daniel Mattox retweeted
C-mannosylation of tryptophans is critical for receptor function and trafficking in metazoans, viruses, and malaria parasites. I am thrilled to finally present the structural basis of this mechanistic puzzle! Thank you @ethangbaus, Kosslab, @reymondgroup! nature.com/articles/s41589-0…
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Daniel Mattox retweeted
A pleasure and a privilege to be assessor again at #CASP15. A mix of spectacular success and the occasional intriguing failure. Looking forward to hearing from the predictors and discussing future directions. Thanks @AJSimpkin @rmk_ccp4 @shah_comp526 @DavidLMurphy3 Filo and Luc.
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Daniel Mattox retweeted
Our preprint on OpenFold, our trainable reproduction of AlphaFold2, is finally up (biorxiv.org/cgi/content/shor…)! Since we open-sourced parameters in June, we've trained the model to high accuracy more than 50 times, on a variety of datasets. Here's what we learned (a lot) -> (1/19)

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Daniel Mattox retweeted
16 Oct 2022
2 hours of cooking just to eat in 10 minutes and now I've gotta wash everything
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Daniel Mattox retweeted
BREAKING NEWS: The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”
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Daniel Mattox retweeted
GOODBYE BASEBALL. HELLO POSTSEASON.
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Daniel Mattox retweeted
Preprint from Philip Bradley where he creates a version of AlphaFold to model TCR:peptide-MHC interactions. Benchmark is far from perfect, but the paper shows that deep learning-based structural modelling is a possible strategy to predict TCR specificity. doi.org/10.1101/2022.08.05.5…
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Daniel Mattox retweeted
14 Jul 2022
1/6 Can #AlphaFold learn from & - labeled data to predict peptide binding better? w/ Phil Bradley @JustasDauparas @minkbaek @Mohamad_Abedi David Baker we present joint structure prediction-classification fine-tuning of #AF2 to classify pMHC binding.@UWproteindesign @fredhutch
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Daniel Mattox retweeted
May 5 is a national day of awareness for missing and murdered Indigenous women. For more than a year, reporters across @usatoday network have worked together to examine factors contributing to the crisis and how laws have largely failed to address it.#MMIW usatoday.com/in-depth/news/2…
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Daniel Mattox retweeted
Hi Joe President, I have a question
29 Jun 2020
Today's decision reaffirmed that states can't put in place laws that unduly burden a woman's right to make her own health care decisions—but the fight isn't over. As President, I'll codify Roe v. Wade and protect a woman’s constitutional right to choose. medium.com/@JoeBiden/my-stat…
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Daniel Mattox retweeted
Studying protein without its glycans is like studying a bird without a single feather; even the best-designed and performed study will never see it flying… Our review on developments and perspectives in high-hhroughput glycomics just got published. academic.oup.com/glycob/adva…
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14 Feb 2022
Kendrick Lamar is officially retired
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A view of today’s afternoon hail storm from west Seattle @KSeattleWeather
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Daniel Mattox retweeted
Episode 40 | Help Is On The Way Mr. President #PensForBiden
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Daniel Mattox retweeted
Have you ever heard of a mysterious region called "killer immunoglobulin-like receptor (KIR)", which is critical for innate #immunity?🧐We analyzed this complex region by deep target sequencing and devising a new #bioinformatics tool @CellGenomics ! cell.com/cell-genomics/fullt…
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Daniel Mattox retweeted
When I visited 3rd and Pine I met an undocumented immigrant struggling to find employment, a woman who survived domestic violence, and a man who has spent half his life selling drugs and merchandise on the sidewalk. These are the people of 3rd and Pine. thestranger.com/slog/2022/03…
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Daniel Mattox retweeted
New >> Last year I wrote about the so-called “gentrification building” TikTok was hating on that was actually affordable housing. Now, the talented @ranjchak has turned my article into an amazing 10 minute YouTube video!
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Daniel Mattox retweeted
Q379 A genetic condition that affects about 1 in 50,000 infants is added to newborn screening. The assay for the condition has 99.9% sensitivity and 99.9% specificity. An infant has a positive result. Based on this, what is the (approximate) chance the child has the condition?
15% 0.01%
40% 2%
15% 98%
30% 99.9%
924 votes • Final results
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