Twitter account of the Daub lab at Karolinska Institutet
Joined November 2015
- Tweets 124
- Following 100
- Followers 208
- Likes 37
26 Photos and videos
🌐We've implemented this annotation strategy on a user-hosted web platform, enabling easy data import, query, and export, making it perfect for both internal documentation and large-scale collaborations
🔗 doi.org/10.1093/gigascience/…
1
328
🔑 With controlled vocabularies and required fields, we've enhanced the consistency and ease of annotating sequencing experiments, making data more comparable and accessible. #research #genomics #sequencing
Explore more: 🔗 doi.org/10.1093/gigascience/…
2
52
🧬 Our annotation structure covers everything from biological sample prep to library creation, sequencing, and processed files, ensuring data quality, comparability, and ease of use across experiments. #bioinformatics #dataquality
Explore more: 🔗 doi.org/10.1093/gigascience/…
1
1
203
📊 We developed a structure to capture all experimental details for better data sharing. #sequencing
#dataannotation
doi.org/10.1093/gigascience/…
58
🧬 We explored the regulatory landscape from zygote to organogenesis, revealing the unique topology & chromatin features of active regulatory elements. Fascinating connections for developmental studies! #epigenetics #genomics
Explore more: 🔗 danio-code.zfin.org
#devbio
30
🌱 With 140,000 cis-regulatory elements mapped across zebrafish development, we’ve identified distinct regulatory classes based on their activity in time and space. Major insights for developmental biology! #zebrafish #genome
Explore more: 🔗 danio-code.zfin.org #genomics
32
🔬 We’ve curated a comprehensive dataset of 1,802 genomic data sets, combining unpublished & re-analyzed data to refine zebrafish annotations, aiding experimental design and advancing developmental genomics. #research #bioinformatics
Explore more: 🔗 danio-code.zfin.org
1
34
🚀 The international DANIO-CODE consortium has the systematic functional annotation program for #zebrafish, a key model in embryonic development and disease research!
Explore more: 🔗 danio-code.zfin.org#genomics #devbio
24
6 Nov 2024
🚨 New Publication Alert! 🚨 The DoGA Consortium has unveiled a groundbreaking canine genome annotation in Nature. This atlas of promoter & gene expression across 100 tissues in dogs, embryos & wolves sets a new standard for genetic research.
nature.com/articles/s41467-0…
3
196
🧪Asthma-linked SNPs such as those near the SBNO2 and SLC19A1 genes coincide with enhancer regions, shedding light on gene regulation mechanisms in childhood asthma.
#SNPs #EnhancerOverlap #AsthmaGenetics
sciencedirect.com/science/ar…
84
🧬A signature of 91 enhancers distinguished between children with severe and mild asthma as well as controls. Discover more here:#duablab #AsthmaResearch #Genetics
doi.org/10.1016/j.heliyon.20…
1
55
8,289 identified enhancers linked to mild and severe asthma in children. Read below how this can impact future treatments. #duablab #AsthmaResearch #Genetics
sciencedirect.com/science/ar…
1
64
Publication Alert! We´re excited to announce that our research on the gene regulatory enhancers in severe and mild asthma in children in Heliyon. Uncover how these findings could lead to new therapeutic strategies. Read the full article here:
sciencedirect.com/science/ar…
1
79
Challenging bioinformatics postdoc position @karolinskainst working with gene regulation in the brain: behaviour and psychiatric conditions in dogs, wolves and humans. With collaborator @HannesLohi
ki.varbi.com/en/what:job/job…
#postdocposition #Bioinformatics
2
4
Daub Lab retweeted
4 Jul 2022
The comprehensive atlas of developmental regulatory elements in zebrafish is published today in @NatureGenet nature.com/articles/s41588-0…. In addition to the BioRxiv submission x.com/daniocode/status/14253… in this paper we added further resources and results. (1/n)
ALT black and white line genome browser track lines forming different developmental stages of zebrafish in the style of the album cover unknown pleasure by joy division.
ALT List of research highlights: Highlights • 1,802 samples, 38 stages, 38 labs, 19 assay types • precise TSS, alternative promoters, promoter architecture classes • developmental TF activity-qualified TFBS prediction • >140,000 cis-regulatory elements, single-cell based cell-type specificity • new visualisation of epigenetic profiles, new functional subclasses • H3K27ac-rich ensembles support early expression of developmental factors and long-range regulation • vertebrate epigenomic landscape conservation by anchored projection tool • vertebrate regulatory element equivalence without sequence conservation
11 Aug 2021
DANIO-CODE is proud to share our findings and a huge multi-genomics resource on the regulatory elements in the development of #zebrafish. We analyzed 1,802 previously (un)published sequencing data sets across 38 developing stages and 21 assay types. (1/n) biorxiv.org/content/10.1101/…
ALT Screenshot of the title and authors of the paper.
ALT bubble chart of all available datasets per zebrafish stage
3
46
134
Daub Lab retweeted
25 Feb 2022
Your #postdoc mission with @DogGenome, should you accept it, is to find how regulatory elements determine behavioural differences between different dog breads and wolfs, and how these are related to human psychiatric conditions.
nature.com/naturecareers/job…
2
3
Help us as #postdoc at @karolinskainst and @DogGenome to find out how brain region-specific gene regulatory elements determine behavioural differences between dog breads and wolfs, and how they might be related to human psychiatric conditions. #Jobs #postdocjobs #Bioinformatics
1
4
6
Here the link to the open call ki.varbi.com/se/what:job/job…
1