New Science Blog: Why has AI advanced faster in coding than in biology? To agents, bio databases are like cities built before cars—maddening to drive in because they're designed for different traffic. How do we build infrastructure agents can use? anthropic.com/research/agent…

We vibecoded a Slack app that detects bioRxiv and medRxiv links posted to our lab's #papers channel, and auto-posts the title authors abstract for easy previewing Posting the Github repo here - Free to install/deploy in case anyone else finds it useful github.com/rsatija/biorxiv_p…

Tie, who has called herself Biotech Barbie, focuses her entrepreneurial ambitions on a controversial goal: altering the genome of human embryos to prevent genetic disorders go.nature.com/4oiHPV3

Congratulations to Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi for this year's Nobel Prize in Physiology or Medicine. It also demonstrates the fairness of the prize, as Mary Brunkow is a Senior Program Manager (not a professor) at the @isbsci. hood.isbscience.org/people/m…

Was great to chat about virtual cells and @arcinstitute with @JorgeCondeBio and @eriktorenberg on the @a16z pod. More next week!

So for 5 years, “offline” has been the #1 request. Today, thanks to the perseverance of our engineering team, @NotionHQ finally works offline. Your ideas don’t need Wi‑Fi to exist! For Notion community: thank you for your patience while we built this right. This is a journey, I want to share what we had to invent to make this real... 1/n

After four and a half years of building, I’m beyond excited to announce today family planning via genetic matching on @nucleusgenomics. Imagine knowing nearly every possible genetic outcome for you and your partner’s future children, starting with your future children’s risk of inheriting over 900 diseases. In the future, all couples everywhere will check their genetic compatibility before having children. In doing so, couples can choose not to pass down hereditary disease to their kids. This is what modern genomic science is about — building tools that lets anyone, anywhere be healthy and have healthy children. What better way to announce genetic matching than syncing with @MollySOShea? Watch to find out if we’re compatible😉

For #AI prediction of protein structure, now there's Massive Fold to save cost and time nature.com/articles/s43588-0… @NatComputSci @GBrysbaert and #AlphaFold3 just went open-source nature.com/articles/d41586-0… @Nature @ewencallaway

Crits, insults i llançament de fang contra el rei, Mazón i el govern a Paiporta bit.ly/3UBFqIu #DanaPaísValencià3Cat

A central mistake in biology was to name genes. This over-simplification made reconciling what is happening on the molecular level a mess - it's not rare to find reports of opposite mechanisms in different contexts, claimed involvement in dozens if not hundreds of different processes, sometimes inhibiting and sometimes amplifying and most of the time being oblivious to the potential for sequence-level variation. Nobody would be surprised about this diversity of findings if we instead recognized genes as (sometimes quite lengthy and complex) pieces of sequence that carry state and interact with and are interpreted by their environment - often producing dozens of gene products that are in turn themselves context-dependent and modulated. Naturally, such a highly amorphous composition of objects has many diverse effects, and masking this complexity behind a single name more often than not ends up being a harmful abstraction. The primary role of gene names then is to give us the false appearance of comfort in the face of enormous biological complexity. One under-appreciated potential of the emergence of AI tools in biology is to undo this mistake, and - instead of assuming it away - extend our ability to lean further into this complexity.

My meager education in biology and evolution gave me the mistaken impression that evolution optimized everything. But it didn't. One example is the recurrent laryngeal nerve (RLN). It goes from behind your ear, loops down below your aorta, and then back up to the voice-box 1/2

poca broma amb Bon Area, un datacenter a guissona amb plaques solars i tota la pesca