We're the Dray lab. We like chromosomes and study DNA repair and recombination at UTHSCSA. Tweets are a group effort, sharing science we like.
Joined March 2018
- Tweets 472
- Following 1,157
- Followers 1,179
- Likes 2,171
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DrayLab retweeted
30 May 2025
A three year postdoctoral position is available in my group, investigating plant centromere structure, function and evolution @plantsci
jobs.cam.ac.uk/job/51488/
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It is going to be a great conference, join us! There is still time to register!
6 Mar 2025
Update on ##Recombination25 Conference! 🚨
📅RD & PS Deadline: 13th March 2025. DON'T MISS OUT!
🌟Grants are available for students, postdocs & junior investigators!🌟
For more details, visit bit.ly/41v8IuK or email Felicity at 📧felicity@fusion-conferences.com
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DrayLab retweeted
1 Nov 2024
Just published📢 Our new forum article on Fc-optimized checkpoint antibodies for cancer therapy. New to immunotherapy and antibody engineering? This one’s for you! Co-authored with Alan Korman. @TrendsMolecMed #CancerImmunotherapy #FcEngineering
sciencedirect.com/science/ar…
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Thrilled to have @maria_spies visit @uthscsa today! Looking fwd to one of her superb seminars :)
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DrayLab retweeted
29 Oct 2024
Free scientific illustrations for biologists! 😍
@NIH has released a library of 500 free scientific illustrations to create figures, presentations, and illustrations!
all freely available in the public domain.
Retweet and spread the message!
bioart.niaid.nih.gov/
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Collaborative paper alerts! The 1st on PDL1 role in DDR is being proofed rn so I'll post next week. 2nd is this beauty from the @PatrickSungLab "Distinct roles of the two BRCA2 DNA binding domains in DNA damage repair and replication fork preservation" biorxiv.org/content/10.1101/…
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Hey science peeps! I get a ton of requests to edit manuscripts. Accepted one, obviously written by AI. Ran it, came back 100% AI,0% human, 5 different detectors. Today, nasty email from editor in chief telling me they don't accept my rejection, and to send it 4 review 1/3
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First of all, the nerves! I am not on payroll, reviewers are not on payroll. Why are we to waste time we don't have on a machine written manuscript? As far as I am aware, AI is not accepted by main publishers (yes, small title from one of the big publishing groups).
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2nd, AI is getting better everyday. We should be clear that articles need to be written by people and based on real data now, as soon enough there won't be a call to be made. There are way too many new paper submissions for all of them to be real. Anyone else feels like me? 3/3
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Hello, DNA repair Tweeter peeps! We have a fab cryo-EM facility but they cannot take just any project I throw at them (time constraints scientific choices). Who is your go to cryo-EM facility? Please contact me directly if you're a structural core with some time or interest!
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New paper alert! Aurkin-A, a TPX2-aurora a small molecule inhibitor disrupts Alisertib-induced polyploidy in aggressive diffuse large B cell lymphoma published today 1/3 authors.elsevier.com/sd/arti…
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Not going to lie, this one took some serious effort! Very enjoyable collaboration with the Mahadevan lab @UTHealthSAMDA @UTHSAResearch where we find that Alisertib, an ATP site inhibitor of Aurora A kinase, induces cell cycle dysregulation and polyploidy in DLBL 2/3
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Polyploidy is bad as it promotes drug resistance is linked w/ poor outcomes. Thankfully, the combination of alisertib and Aurkin A, an Aurora A TPX2 site inhibitor, ↘️ polyploidy and ↗️ apoptosis. Basic science at the service of drug development, stay tuned for translation! 3/3
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New work from the @leunglaboratory! @UTHealthSA @UTHSAResearch rdcu.be/dJzfA Evolved histone tail regulates 53BP1 recruitment at damaged chromatin in @NatureComms
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I was a little slow posting this, but congrats to PJ *doctor* Conway on graduating! Joint mentoring with Dr Mahadevan was a breeze. Keep an eye out for PJ's beautiful paper on cell cycle analysis and polyploidy in Lymphoma, which I hope will be accepted and shared here soon!
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What a great way to start the day. This superb work from the Pillai lab, driven by Prajwal Boddu and a little help from us @bdelapenavalos is finally in print @MolecularCell Highlight: SF3B1 oncogenic mutations reduce RNAPII gene-body elongation rate. sciencedirect.com/science/ar…
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Amazing new work from the Pickett lab @hildaApickett and collaborators! This story on #EYA #phosphatase is gorgeous, complex, well done Hilda and everyone in the lab for getting it published! Can't wait to collaborate again and share the follow up stories nature.com/articles/s41467-0…
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