Using the yellow-legged gull as a model species, we analysed how energy expenditure varies across feeding habitats, combining GPS 🛰 data, accelerometry, and fisheries activity 🎣.

💥Excited for the publication: "Accelerometry and the Capacity–Performance Gap: Case Series Report in Upper-Extremity Motor Impairment Assessment Post-Stroke" 🔗brnw.ch/21x3f0t 📌 #StrokeRehabilitation #MachineLearning #WearableSensors #BiomedicalEngineering

🚨 The UK Biobank just proved it: we are unwitting subjects in a vast, uncontrolled, population-scale epigenetics experiment — and dementia is exploding as the bill comes due. A Nature Reviews Neurology Perspective (April 2026) celebrates 20 years of the UK Biobank: >500,000 deeply phenotyped participants now hitting peak dementia age. Brain imaging, accelerometry, omics, health records — all tracking a “distinct opportunity” as neurodegenerative cases surge. But let’s call it what it is from a quantum biology lens. This isn’t neutral observation. It’s real-time monitoring of a chaotic, multi-generational intervention with zero informed consent and no off-switch. Chronic circadian desynchronization mitochondrial overload layered xenobiotic stress is rewriting our epigenome in real time: • ALAN (all-night blue light) shattering central/peripheral clock gene oscillations and peroxiredoxin rhythms • 4G/5G towers constant RF-EMF disrupting cryptochrome magnetoreception and electron spin states in mitochondria • Glyphosate ultra-processed food matrices destroying gut-mitochondria crosstalk and one-carbon metabolism • Economic grind, overwork, and lockdown trauma driving relentless sympathetic dominance and cortisol chaos • Injectable experiments layered on top during peak vulnerability Result? A population that is overfed yet micronutrient-starved, sedentary under artificial light, and denied proper mitohormetic signals (fasting, cold, intense movement aligned with natural light/dark cycles). Instead we get chronic pseudo-stress: mTOR jammed, NAD depleted, SIRTuins silenced, histone acetylation dysregulated, DNA methylation drifting toward disease. Quantum biology 101: light, timing, and electromagnetic fields are primary controllers of redox, proton motive force, and epigenetic machinery. We’ve turned the entire modern environment into a constant disruptor of those cues. No wonder dementia is rising sharply in the Biobank cohort. The cumulative circadian-mitochondrial debt is maturing. This isn’t “aging.” It’s accelerated decoherence of the living quantum system we call a human being. Mainstream science will keep publishing correlations and calling for more funding. Quantum biology practitioners see the mechanism: restore circadian entrainment, remove the chronic disruptors, reintroduce controlled mitohormetic stressors — and resilience returns. The experiment continues. The data is pouring in. The question is: how many more “opportunities” will it take before we admit the intervention itself is the disease? #CircadianHealth #QuantumBiology #Mitohormesis #UKBiobank #Epigenetics #5G #Dementia

■ Ref info: Terrier, Philippe, and Sophia Piergiovanni. "An accelerometry-based marker of gait automaticity is lower in older adults reporting recent falls." Gait & Posture (2026): 110205. ■ Ref link: doi.org/10.1016/j.gaitpost.2… ■ note link: note.com/super_human/n/n329b…

Sources, in the order they appear: 1. Smell loss as an early prodromal sign: established in the PPMI prodromal cohort (hyposmia), Siderowf et al, Lancet Neurology 2023. pubmed.ncbi.nlm.nih.gov/3705… 2. Acting out dreams (REM sleep behaviour disorder): 6.3% convert per year, 73.5% by 12 years, n=1,280, 24 centres. Postuma et al, Brain 2019. pubmed.ncbi.nlm.nih.gov/3078… 3. Smartwatch (wrist accelerometry) flagged Parkinson's up to 7 years before diagnosis and outperformed genetics, blood and lifestyle models. Schalkamp et al, Nature Medicine 2023. pubmed.ncbi.nlm.nih.gov/3740… Caveat worth saying plainly: the lead time is real, but the absolute accuracy at a population level is still low. It's a screening signal, not a diagnosis. 4. Retinal scan (OCT): GCIPL and INL thinning showed up on average about 7 years before a Parkinson's diagnosis. Wagner et al, Neurology 2023. pubmed.ncbi.nlm.nih.gov/3760… 5. Skin biopsy (Syn-One test): cutaneous phosphorylated alpha-synuclein detected in 92.7% of Parkinson's patients (89 of 96), with 3.3% of controls positive, n=428 enrolled across 30 sites. Gibbons et al, JAMA 2024. pubmed.ncbi.nlm.nih.gov/3850… Commercially available in the US via CND Life Sciences. 6. Spinal-fluid seed amplification assay (SAA): about 99% sensitivity in classic sporadic Parkinson's, and it turns positive in prodromal people (RBD, hyposmia) who have no motor symptoms yet. Siderowf et al, Lancet Neurology 2023, PPMI / Michael J. Fox Foundation. pubmed.ncbi.nlm.nih.gov/3705… The 2024 shift: a biological staging system (NSD-ISS) now defines Parkinson's by the alpha-synuclein protein detected in vivo, not by symptoms. Simuni, Hoglinger et al, Lancet Neurology 2024. pubmed.ncbi.nlm.nih.gov/3826… The smell story: Joy Milne, the Scottish nurse who could smell Parkinson's, led to the sebum-odour work in Barran's lab at the University of Manchester. Honest caveats: most of these detect risk, not certainty. The skin and spinal-fluid tests are the most clinically established; the smartwatch and retinal signals are population-level research findings, not personal verdicts.

Cohort study (470 pregnancies, accelerometry): Sitting ≥10h/day → 2.2x higher risk of adverse outcomes (vs 7h). Light activity 7h/day → half the risk (vs 3h). More daily steps → 24-33% lower risk. Long sedentary bouts (≥60min) are worst. Standing (even without walking) helps

13/ Measurement caveats. Wrist accelerometry conflates sleep with time in bed and misclassifies SB more than thigh-worn devices would. Cognitively stimulating sedentary time (reading, puzzles) gets lumped with passive SB. Wear period was 2021–23 (post-acute COVID behavior baseline 👀 ).

4/ Design: 2,529 adults, 50 at baseline. Memory and fluency slopes estimated across waves 1–9 (up to 17 years), then linked to wave 10 accelerometry (8 days, wrist-worn) using compositional data analysis (so the 24-hr day is treated as the zero-sum budget it actually is).

8 ) The accelerometry probably isn't the most reliable tool to measure sleep quality. The authors mention that it "does not directly measure sleep stages or architecture and should therefore be considered a proxy-based method rather than a diagnostic tool."

Important conversation on how accelerometry can capture subtle, real-world longitudinal changes in disability in people with multiple sclerosis - often before these changes are fully evident in the clinic. Worth listening to. youtu.be/0yeBiPiTybY?si=jrpY… via @YouTube

Journal of Clinical Sleep Medicine: Sleep in ME/CFS shows marked night-to-night fluctuation under free-living conditions—results from a matched case-control study "Using week-long wrist accelerometry, this study shows that under free-living conditions sleep in ME/CFS is characterized not only by impaired sleep efficiency but also by pronounced night-to-night variability, despite relatively stable bedtime compared to controls." Read more: link.springer.com/article/10… #MECFS #pwME #MyalgicE #Sleep #UnrefreshingSleep

Accelerometry-Derived Physical Activity Levels and Mortality in Hemodialysis Patients: A Prospective Cohort Study bit.ly/4j9tE3e (FREE temporarily) @yohei_doi

🏃 When you exercise matters as much as how much you exercise. UK Biobank — 3,143 patients with Type 2 Diabetes Wrist accelerometry → 3 activity timing clusters 🌅 Morning peak (6-9h): ↓ CVD risk ✅ ↓ Mortality risk ✅ 🌤️ Late-morning peak (9-12h): ↓ CVD risk ✅ ↓ Mortality risk ✅ 🕐 Uniform daytime activity: → Baseline reference risk 👉 Both morning clusters outperformed uniform daytime activity The message is simple: Front-load your physical activity. Move in the morning. Your heart will thank you. ⏰ It’s not just about steps — it’s about timing. #Cardiology #PhysicalActivity #Type2Diabetes #CVD #Prevention #ExerciseMedicine #UKBiobank

They just did „Bird-Watching“ in Argentina before they boarded the MV Hontius? A person named Mirjam Schilperoord-Huisman is mentioned in a 2019 report regarding fieldwork in Norway concerning Arctic-breeding migrant geese, along with Christine Verscheure and Leo Schilperoord. What’s this? - Animal BioTelemetry Nesting attempts and success of Arctic-breeding geese can be derived with high precision from accelerometry and GPS-tracking.

SVM-90 is computationally lean and works across sampling rates and interrupted data, enabling use across diverse accelerometry devices and studies. Future studies are needed. jacc.org/doi/10.1016/j.jchf.… #JACCHF #HeartFailure #6MWD

Within-person worsening in activity fragmentation using accelerometry may represent an early compensatory strategy for reduced physiologic reserve and serve as an early indicator of #MultipleSclerosis progression. Study from @HopkinsMedicine ▶️ journals.sagepub.com/doi/ful…

A method estimated walking loading rate from accelerometry in the frequency domain. Rates decreased from foot to pelvis, differing by frequency. Measures correlated with time-domain metrics, stronger at low frequencies, offering segment-specific insight. doi.org/10.1177/095441192513…

Tf is 3D accelerometry... You guys do it at your setup dada? :|

This appears to be a hyperkinetic movement disorder involving both hands with fine ie low amplitude and high frequency, rhythmic flexion-extension movement of the wrists on adopting the hands forward posture but not at rest It looks like a postural tremor However the movement also exhibits some jerkiness which is more prominent in certain fingers like the index finger Phenomenologically I would place this as 1. Postural form of action tremor 2. Cortical myoclonus 3. Polyminimyoclonus d/t LMN disease but it should have occurred at rest as well Etiologically I would think of Postural tremor --> enhanced physiological tremor (EPT) > essential tremor (ET) [I am thinking EPT over ET because of the low amplitude and the high frequency of the tremor] Cortical myoclonic tremor which is often familial Additionally, My major ddx = ET ET is a kinetic >> postural tremor So I will ask for drawing of Archimedes spiral and pouring of water from glass --> glass It really brings out the kinetic nature of the tremor Lastly if all else fails Electrophysiological analysis with surface EMG and 3D accelerometry #MedTwitter #NeuroTwitter #MovementDisorders