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I rarely see them this large anymore. They're usually caught earlier. #PediPath #OBPath
molar pregnancy!!! is does not get better than this!!
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Educational Pearl 🧠🧫 | Placenta Time Chorangiosis = increased capillaries in the terminal chorionic villi 📌 ≥10 capillaries in ≥10 villi in ≥3 low power fields of the placenta = diffuse chorangiosis 👉 Reflects chronic fetal hypoxia 📌 Associated with diabetes, smoking, high altitude, and IUGR 📸 Photos by Dr. Youssef @Bahaaeldin89 #PlacentaTime #EducationalPearl #PlacentalPathology #Chorangiosis #OBPath #PerinatalPathology #PathResidents #MedEd #PathologyX
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Replying to @leon_metlay
@leon_metlay Would you call this a yolk sac remnant? (POC specimen, missed abortion) #placentapath #obpath
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Wrong place at the wrong time. x4, x10, x4, x10 #PediPath #OBpath #Pathmatch2026 #Path2Path
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Not placenta percreta. x4 and x10 #Placenta #PediPath #OBpath
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I think this is a good example of villous linear subtrophoblastic mineralization, a distinctive pattern that has been associated w/ congenital anomalies, Trisomy 21, anencephaly, & antenatal Bartter syndrome. This case: cytogenetics = Trisomy 21 #obpath #placentapath
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1st trimester missed abortion What's being shown here? Any guesses on what the karyotype confirmed? #placentapath #obpath
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Example of villi with negative stromal cells but few/rare positive cytotrophoblast Interested to see how many people have seen this discordant pattern! (3/3) #obpath #placentapath @leon_metlay @JasmineSteeleMD
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#obpath - POC: morphologically looks like complete mole; ploidy analysis = diploid p57 is a bit strange: villous stromal cells are uniformly negative, but a subset of villi have few p57 cytotrophoblast Per PMID: 30500280 - a few p57 cells are OK. Is that your experience? (1/3)
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#placentapath #obpath I have a favor to ask! If you use a dissecting microscope to evaluate for villi, what's the make/model🔬? Either I don't know how to properly use the one in my lab, or it's the wrong kind 🤷‍♀️ Thank you!! 🙏 @leon_metlay @JasmineSteeleMD @E_Heidi_Cheek
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ISGyP 166.4 39 years.  Hysterectomy for placenta accreta.  Submucosal fibroid noted. Diagnosis: Inflammatory myofibroblastic tumour.  ALK IHC and FISH positive. Inflammatory myofibroblastic tumor (IMT) is related to abnormalities in the ALK gene.
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Intraplacental hepatic heterotopia (benign, just a quirk of development!) #placentapath #obpath #PathTwitter
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Placentophiles! Here's something incidental and fun. Ever seen one? Answer posted below. #placentapath #obpath #PathTwitter
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Do you see what I see? IUFD at 35 weeks, likely due to cord accident (true knot) #placentapath #obpath
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p57 IHC and DNA ploidy by flow cytometry 2/2 #OBpath #generalpath #pathresidents
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Missed abortion - your Dx? 1/2 #OBpath #generalpath #pathresidents
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Hey #PathTwitter! I'm Jose Manuel Martin, an IMG from 🇻🇪 and Research Fellow at @MGH_RI excited to be applying to #Pathology for this #Match2025 🔬. I have an interest in #GYN and #OBpath. I'm also a cinema enthusiast 📽️. Looking forward to connect with this great community!
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I have finally dug myself out from a pile of placentas 🙌 #IYKYN #placentapath #obpath
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POC, demise @ 7 weeks Possible embryonic tissue or early umbilical cord?🤷‍♀️ #obpath #placentapath
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