We just hit MySQL-level performance with Dolt (0.99x on Sysbench)! 🚀 Full benchmarks: ow.ly/S9FV50XCZT3 #DatabaseEngineering #DevOps #MySQL #DatabasePerformance #OpenSourceDatabase #DataOps

HSADab2025: AI-powered Modelling of Human Serum Albumin - A significant update to the HSADab database, incorporating AI-powered modelling to enhance our understanding of Human Serum Albumin (HSA) interactions. The new webserver hsadab.cn offers instant prediction of HSA binding affinities for drug-like molecules, a comprehensive affinity and structure database, and deep-learning assisted docking structures. - The database now includes the most up-to-date thermodynamic data (up to June 2024) and uses advanced machine learning predictors, such as fine-tuned large language models and graph-based neural networks, to achieve chemical accuracy in binding affinity predictions using just the SMILES representation of molecules. - A detailed analysis of HSA's protein conformational space reveals a clear distinction between bound and unbound states, providing crucial insights for docking studies. The research also benchmarks traditional docking protocols on HSA, identifying PLANTS as a top performer, which contrasts with the widespread use of AutoDock derivatives. - The docking bank has been significantly expanded with global docking results from state-of-the-art deep-learning tools like DiffDock, AF3, Boltz-1, and Chai-1, offering a more comprehensive structural basis for HSA-ligand interactions and enabling a deeper understanding of the binding process. - The study demonstrates the superiority of ML predictors over traditional physics-based screening methods in estimating HSA binding strength, with the ML models achieving near chemical accuracy without requiring 3D interaction descriptions of protein-ligand complexes. - All data entries, including the updated affinity, docking, and structure databanks, as well as the SMILES-to-affinity ML predictors, are freely available online, facilitating further research and applications in the field of HSA-drug interactions. 💻Code: github.com/proszxppp/HSADab 📜Paper: doi.org/10.26434/chemrxiv-20… #HumanSerumAlbumin #AIPoweredModelling #DrugDiscovery #MachineLearning #ProteinLigandInteractions #OpenSourceDatabase

I'm happy to share that our book MySQL Cookbook 4th edition will be translated into Chinese. a.co/d/iLG4DLk #mysql #opensourcedatabase #mysqlcookbook4e @svetsmirnova @OReillyMedia

How have corporate anti-patterns around #opensource changed in the last decade? At our free and virtual #P99CONF, @oxidecomputer's @bcantrill will discuss the changes he's seen over the last 10 years, as well as provide guidance for corporations on what NOT to do. Save your spot today: bit.ly/43RHzlV #ScyllaDB #opensourcedatabase

Listen to Tyler Hannan from ClickHouse at #ApsaraDBForward - Alibaba Cloud Data Management Summit on 25 Jul, 2023 to discover why ClickHouse is the ultimate #OpenSourceDatabase for real-time apps & analytics. Register now for an insightful session from 15:55 - 16:05 (UTC 7) on LinkedIn livestream: linkedin.com/feed/update/urn…

👾 What is the most significant factor impacting Open Source databases strategies? Some might say it's the Cloud, but the honest answer might surprise you. A great talk by Peter Zaitsev on what we should look for in 2023. #Confoo #TechConference #OpenSourceDatabase

Enterprises looking for a database solution have two choices: free open source software or a well-known proprietary solution. This decision rests on the company’s data needs and budget. 4cit.group/open-source-vs-pr… #DatabaseSoftware #OpenSourceDatabase #ProprietaryDatabase #Database

20 Ekim 18:00'da Craftgate ofisinde ev sahipliği yapacağımız ücretsiz etkinliğin detaylarına buradan ulaşabilirsiniz.-->meetup.com/data-on-kubernete… Konuşmacılar: Alkin Tezuysal | Alexander Zaitsev | Robert Hodges #mysql #kubernetes #opensourcedatabase #dataonkubernetes #DoK #Meetup

MySQL Summit, co-located at Oracle CloudWorld, is coming up on Oct 17! Visit Datavail at Booth #375 to chat with our MySQL experts, and discover all the possibilities of open-source databases. bit.ly/3dSKg1J #mysql #oracle #database #opensourcedatabase #oraclecloudworld

📣 Event Alert: we’re sponsoring & attending #PGConfNYC 2022! Sign-up for 2 days (Sept 22-23) on #PostgreSQL—the leading #opensourcedatabase. And be sure to tune into @ncalerouy and @simonpane’s expert sessions: 2022.pgconf.nyc/ #postgres #LoveYourData

Register for @Percona Live so you can meet with our #OpenSourceDatabase experts in-person at Booth 6 in just days! Pythians Use our coupon code ‘22PythianCustomerDiscount’ for 10% off your registration: #PerconaLive #OSDB eventbrite.com/e/percona-liv…

With a lot of happiness and pride, we announce the press release of our third Advanced Specialization- Linux and Open-Source Database Migration to Microsoft Azure Advanced Specialization. Know More: bit.ly/3bqIcsR #Azure #microsoft #Linux #OpenSourceDatabase #MSRcosmos

Without good #o11y, you cannot get out of reactive mode when it comes to #DatabasePerformance. Percona's PMM is a good low-friction tool to provide visibility into the performance of your #OpenSourceDatabase over time. distributeddba.com/blog/data…

Migrating to an open source database platform like MySQL or PostgreSQL? Here's one way to do it, free trials included. #DeveloperTools, #OpenSourceDatabase, #DatabaseTools okt.to/VOM8yv

Migrating to an open source database platform like MySQL or PostgreSQL? Here's one way to do it, free trials included. #DeveloperTools, #OpenSourceDatabase, #DatabaseTools okt.to/SN5rit

Migrating to an open source database platform like MySQL or PostgreSQL? Here's one way to do it, free trials included. Part 3. #DeveloperTools, #OpenSourceDatabase, #DatabaseTools okt.to/X1fsvn

There are many #OpenSourceDatabase solutions to choose from. How do you decide? This blog compares the most popular databases by performance, benefits, and drawbacks of each type. >> ter.li/fhxxgf

Ik ben vanavond geattendeerd op het project Common Voice van Mozilla. Waar het op neerkomt is dat ze een opensourcedatabase maken om machines te leren hoe mensen praten én dat er een groot gebrek is aan vrouwenstemmen. voice.mozilla.org/nl

Download this paper now: "NMReDATA, a standard to report the #NMR assignment and parameters of #organiccompounds" okt.to/gJR1mX @Mestrelab #NMRspectroscopy #structuralchemistry #NMRchat #opensourcedatabase

.@grafana raise $24M to build out #dataobservability platform read about it in this Q&A between @TechJournalist and @nopzor #RajDutt Grafana CEO #opensourcedatabase searchdatamanagement.techtar… @TechNewsEditor @craigstedman