Structural bio(techno)logist | #NewPI at @MaxPerutzLabs | Mobile DNA lover & CRISPR newbie
Joined October 2017
- Tweets 378
- Following 553
- Followers 1,032
- Likes 730
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Pinned Tweet
7 Oct 2023
š¢ I have two open @ERC_Research fully funded #postdoc and #PhD positions in my lab at @MaxPerutzLabs on the @viennabiocenter campus. We are looking for structural bio(techno)logists with a passion for nucleic acid binding proteins and genome editing.
Deadline for PhD: Oct 15th
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Irma Querques retweeted
May 12
1/9 New preprint from the Sternberg Lab in collaboration with the Nishimasu Lab! We uncover how the DRT3 antiphage immune system pairs two reverse transcriptases, one RNA-templated and one protein-templated, to build a double-stranded DNA effector. doi.org/10.64898/2026.05.04.ā¦
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Happy to share the first preprint from our lab now online on bioRxiv!
Congrats to Mateusz, Giada, Seraina, and all authors (BRAVI!). Great collaboration with the Jinek lab and @SternbergLab
biorxiv.org/content/10.64898ā¦
@MaxPerutzLabs @univienna
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Irma Querques retweeted
Congratulations to first author @AritzRoa for his amazing work on how T4 delivers its genome and blocks other phages from injecting theirs š„³ Check out his beautiful movieš½ļø Thanks to all authors and collaborators MLNielsen and @AHarms485 tinyurl.com/2kvva646 #cryoEM #phage
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Irma Querques retweeted
4 Dec 2025
š“ Great opportunity to perform a PhD in different labs (including ours) š
4 Dec 2025
#CIBjobOffer
10 research positions available at the First Call of #SYNBIO-CSIC doctoral network for advanced training in Synthetic and Engineering Biology.
Deadline: Feb 26, 2026
Documents and detailed steps šlifehub.csic.es/synbio-cofunā¦
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Irma Querques retweeted
26 Nov 2025
Excited to share our latest research in @NatureMicrobiol . We uncover hundreds of inhibitory interactions between common chemical pollutants and human gut bacteria. @kiran_r_patil @MRC_TU A threadš§µ(1/10) nature.com/articles/s41564-0ā¦
ALT Illustration showing pesticides sprayed on vegetables, reaching gut bacteria, alongside a chip representing machine learning predicting their effects.
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Irma Querques retweeted
24 Nov 2025
"In the end, I have come to realize that being authentic at work is not a weakness, but rather a strength." #ScienceWorkingLife scim.ag/489m6bk
ALT An illustration of a woman wearing an axolotl costume in front of an audience, with text: Embracing my silly side makes me a better scientist. I wish Iād done it sooner
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18 Oct 2025
Wooow
17 Oct 2025
New work from @stephentang23 et al. that describes a fascinating set of reverse transcriptases involved in antiviral immunity. They synthesize tandem-repeat cDNAs that resemble telomeres, revealing an unexpected bacterial evolutionary origin of telomerase. Check out the thread!
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EMBLās 2025 Kendrew alumni award recipient may know how to make fairy tales come true.
Irma Querques repurposed the āSleeping Beautyā transposon as a genetic tool for new therapeutics, particularly against cancer.
embl.org/news/people-perspecā¦
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Nature research paper: Protecting double Holliday junctions ensures crossing over during meiosis
go.nature.com/4ndH6UI
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Irma Querques retweeted
24 Sep 2025
in her 1983 nobel lecture, barbara mcclintock presciently described the origins of new species as the aftermath of accidental hybridizations
stay tuned for tomorrow, as we stand on her shoulders
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26 Aug 2025
Excited to share my talk at the EMBL John Kendrew Award ceremony about what transposons taught me about science, life, and change along the way.
Big thanks to my mentors, @embl, and my current scientific home @MaxPerutzLabs š
youtu.be/NwIikKS7EWE?si=4s4gā¦
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Irma Querques retweeted
8 Aug 2025
Wrapping up my @ERC_Research-funded @frontiers_media Fellowship at ISTA. In 4.5 months, I gave talks on science journalism, visited Austrian newsrooms, and connected with researchers and journalists from around the world. Grateful for the opportunity and excited for whatās next!
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Irma Querques retweeted
24 Jul 2025
1/16 New pre-print from the Sternberg Lab!
We uncover how temperate phages can use RNA-guided transcription factors to remodel the flagellar composition of their bacterial host and enhance their fitness. Find the preprint and full story here: tinyurl.com/mshwjd77
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Irma Querques retweeted
23 Jul 2025
Temperate phages enhance host fitness via RNA-guided flagellar remodeling biorxiv.org/content/10.1101/ā¦ #biorxiv_micrbio
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Irma Querques retweeted
24 Jul 2025
Hi there! We are lookig for a highly motivated and talented postdoctoral researcher to join our dynamic team starting in 2026. Please see the call for more details! Come on join us! It will be fun! :)
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Irma Querques retweeted
11 Jun 2025
Excited to share my last major PhD work from the @SternbergLab. We discovered a mechanism that initiates transcription at programmable sites, without requiring promoter sequences - a novel mode of transcription regulation in bacteria.
11 Jun 2025
New pre-print(s) from the Sternberg Lab in collaboration with @LeifuChangLab! We uncover an unprecedented molecular mechanism of CRISPR-Cas12f-like proteins, which drive RNA-guided transcription independently of canonical promoter motifs.
Full story here: tinyurl.com/mr3fd493
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Irma Querques retweeted
10 Jun 2025
Excited to see our work published in @ScienceAdvances!
We present RBPseg, a method for structural prediction of #phage receptor-binding proteins.
We applied it to diverse tail fibers and validated the predicted structures using #cryoEM.
Read here: science.org/doi/10.1126/sciaā¦
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Irma Querques retweeted
13 Jun 2025
Exited to share that our RBPseg paper has just come out in @ScienceAdvances. Huge cograts to first author @VKleinSousa and co-authors @AritzRoa, @CloudyKielkopf and @sofos112
#phage #cryoEM #ArtificialIntelligence @UCPH_CPR science.org/doi/10.1126/sciaā¦
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Irma Querques retweeted
Whatās it like to be a postdoc at the Vienna BioCenter? Anna Osnato shares her experience from joining the Institute of Molecular Biotechnology.
The VIPĀ³ PostDoc Program call is open ā apply now for this unique opportunity! training.vbc.ac.at/post-docsā¦
#VBCPostDoc
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Irma Querques retweeted
13 May 2025
Tomorrow Iām joining four amazing colleagues from around the globe to talk about science journalism ā how it can offer clarity, hope, and accountability in uncertain times. Donāt miss it! More info at: ista.ac.at/en/news-events/evā¦
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