SVP @ curie.bio;Former SVP Head of Research @chromamedicine;EIR @ThirdRockV;Reg Med, uBiome group leader/Resp DA co-lead @NovartisScience. Opinions mine

Joined October 2011
216 Photos and videos
The data are one thing, but the individual patient stories bring it to life. This is why we do what we do. Congrats to @RevMedicines and all the people that contributed to this amazing medicine open.spotify.com/episode/1Fu…
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Aron Jaffe retweeted
19 May 2020
Happy birthday to two of my favorite people in the world - Ralph DeBerardinis (@rjdlab), who turns 50 today, and Alan Hall, who would have been 68. In addition to sharing a birthday, Ralph and Alan have quite a bit in common (thread) en.wikipedia.org/wiki/Alan_H…
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Thanks for sharing view, @jrkelly! This is a polarizing issue, as you know. I, for one, do not support breaking access to China-based manufacturing or innovation. It would harm patients, and that MUST remain our Northstar. On the other hand, I think China’s recent advances must be a “Sputnik moment” for the U.S.. For starters, we should stop and reverse the self-inflicted damage created by certain Administration policies, including reduced NIH funding, FDA instability, drug price controls, H1B visa restrictions, and an anti-Vax/anti-science agenda.  Then, we should find smart ways to increase our global competitiveness, including reducing barriers to efficient clinical evidence generation, creating incentives for U.S. clinical trial and manufacturing, and reforming PBMs/340B to ensure reward for the innovator, not the middleman. We can win this competitive race with American ingenuity and resolve, not with walls and barriers!
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A couple of sliders from a vending machine just before a flight. What could go wrong?
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Congrats @bloodgenes !
🚨 Excited to share a new paper in Cell! Human genetics led us to HOTSCRAMBL, a HOXA-locus lncRNA that regulates 🩸#stemcell self-renewal and HOXA9 splicing, with implications for AML. Amazing work by @lvchosen1 with @silvirouskin, @Armstrong_dfci, and many more! cell.com/cell/fulltext/S0092…
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Congratulations to the now Twitterless/Xless Ralph DeBerardinis on being elected to @theNASciences!!!
🌟From the desk of @SJMorrison_: It's a great day for CRI, which now has 2 @theNASciences members. Congratulations to Ralph DeBerardinis, M.D., Ph.D., and his laboratory on this recognition for the quality and impact of their work! #relentlessdiscovery cri.utsw.edu/deberardinis-na…
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Congrats @IOB_Roska and all the awardees!
Apr 21
👁‍🗨We turn science into sight. Congratulations to our Director @IOB_Roska on receiving the 2026 Future Vision Award alongside Connie Cepko & Daniel Ting. A recognition of long-term research now reaching patients. 🎬Watch the short movies: futurevisionfound.org/2026-f… #Vision #Retina #Ophthalmology #Blindness #Neuroscience #ScienceInnovation #VisionRestoration #EyeHealth #BiomedicalResearch
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Couldn’t agree more! As my wife and I tell our two kids - actions have consequences!
“We are losing scientists, we’re losing our IP, we’re losing physicians, we’re losing the best researchers, and we’re going to lose our biosecurity,” Kennedy said. Well, maybe we should STOP all the self-inflicted damage by: funding academic research, attracting best scientists from all over the world with H1B visa program, supporting a strong, consistent FDA without political influence, supporting our public health infrastructure, and supporting scientists!
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Best of luck to all! #bostonmarathon
We are ready for you! See you at the finish! ⁦@bostonmarathon
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RT @brkthroughprize: Congratulations to Jean Bennett, Katherine A. High and Albert Maguire, winners of the 2026 Breakthrough Prize in Life…
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Aron Jaffe retweeted
That Phase 3 overall survival data is in second line #PancreaticCancer which makes the numbers even more astounding. I cannot recall any other example in pancreatic cancer when OS in a Phase 3 trial basically doubled over existing standard of care. statnews.com/2026/04/13/revo…
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Finally, best news of the morning (and something you didn't expect so soon)... Revolution Medicines $RVMD daraxonrasib Ph3 results in second-line pancreatic cancer. Median overall survival in ITT patients (KRAS mutants wild type combined) Dara 13.2 months vs chemo 6.7 months. OS Hazard ratio 0.40
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Aron Jaffe retweeted
Resharing this piece I wrote last year on human genetics and drug discovery. India’s genetic diversity is an underexplored asset, one that can fundamentally reshape how we discover new medicines. This is exactly the direction we’re building towards 🇮🇳 worksinprogress.co/issue/nat…
India’s biotech future will be built on human genetics. We’re starting to lay that foundation 🇮🇳
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