For his award lecture, Matt gave a great talk on the impact of microglial CD33 in Alzheimer's disease progression, providing insights into why it is viewed as a major risk factor in the onset of the disease.
Major step forward in understanding how glycoRNA gets made, defining the chemical linkage provides a path to bridge to biosynthetic pathways that make these glycans!
Exciting news from @tracy6528! 🎉 Check out her latest paper on 'Chemoenzymatic synthesis of genetically-encoded multivalent liquid N-glycan arrays' available online now. 📚🔬 nature.com/articles/s41467-0…
Major insight for how the conserved N-linked glycan in IgG gets sialylated, not in B cells, but in endosomal compartments of endothelial cells during recycling by the FcRn receptor!
Congratulations to all our award winners: Prof Paulson (Hudson Award @jcpJim), Mia Huang (Gin Award @HuangMia), Peter Andreanna (Wolfrom) (@UToledo), Cat Grimes (@CLGrimesLab (Isbell) John/Sharon Verellotti (Horton) #glycotime
Fantastic application of SulFEx chemistry by Liu, Wu and Sharpless in materials science with potential for application in advanced electronics and batteries.
Very early cancer detection in healthy people has been studied with liquid biopsy tumor DNA sequencing & methylation. A new report shows the potential for free glycosaminoglycans, both plasma and urine, for 14 cancer types, especially at stage 1
pnas.org/doi/suppl/10.1073/p…@PNASNews