Associate Professor in Cell Biology at UTSW, studying how organelles are shaped and organized
Joined August 2010
- Tweets 523
- Following 562
- Followers 1,218
- Likes 1,132
31 Photos and videos
Pinned Tweet
19 Feb 2025
Some good news (and fresh science) to break things up! Our work identifying a subpopulation of compositionally unique mitochondria that localize to filopodia and promote cell migration is now online @CurrentBiology! Led by fantastic @madeleinemarlar!
cell.com/current-biology/ful…
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Check out our highlight of the most recent example of subcellular mitochondrial specialization in @CurrentBiology. Be sure to also check out the beautiful work from David Sherwood's lab
cell.com/current-biology/ful…
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A reminder to join us at 12pm ET today!
I'm excited to host the ASBMB LRD seminar series next Thurs 4/9 at 12pm ET. Please join us for talks from @Zak_Bakes (from @Pagliarini_Lab) and Sara Wong (from @Adam_L_Hughes lab) on the intersection of mitochondria and lipid metabolism!
Register here: asbmb.org/meetings-events/lr…
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I'm excited to host the ASBMB LRD seminar series next Thurs 4/9 at 12pm ET. Please join us for talks from @Zak_Bakes (from @Pagliarini_Lab) and Sara Wong (from @Adam_L_Hughes lab) on the intersection of mitochondria and lipid metabolism!
Register here: asbmb.org/meetings-events/lr…
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Jonathan Friedman retweeted
Feb 19
Thrilled to share our work "Recessive PPTC7 deficiency triggers excessive mitophagy to cause a severe inborn error of metabolism with hypomyelinating leukodystrophy" - a collaborative effort documenting the first cases of PPTC7 mutations in humans. 1/n
researchsquare.com/article/r…
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Jonathan Friedman retweeted
Jan 8
Really thrilled to share our work on mitochondrial presequence strength @JCellBiol. We establish quantitative parameters to better define "strong" and "weak" presequences in vitro and in vivo. This work was spearheaded by the ever talented Youmian Yan, a grad student in my lab.
Youmian Yan, @IanofBristol, @nieminm et al. define quantitative parameters underlying the strength of mitochondrial-targeting presequences, and demonstrate that yeast require strong presequences to facilitate select metabolic pathways in #mitochondria. hubs.la/Q03-1x5l0
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3 Sep 2025
Thrilled to announce my official promotion to associate professor with tenure at UTSW! So grateful to all the trainees in the lab for their hard work and proud of their accomplishments over the last several years. This an individual recognition but truly a team effort!
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13 Aug 2025
Does anyone have a favorite mNeonGreen antibody that works well for western and IPs?
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Jonathan Friedman retweeted
29 May 2025
Very excited to share our latest work, “Mitochondrial presequences harbor variable strengths to maintain organellar function,” led by the fantastically talented @WashUBBSB graduate student Youmian Yan. A 🧵
biorxiv.org/content/10.1101/…
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Important to celebrate trainee victories: excited to have @HollyMerta's paper out in @CellReports.
We use TurboID sub-organelle proteomics to map the ER network.
We discover calmin/CLMN, an ER-to-actin tether regulating focal adhesions & cell motility.
sciencedirect.com/science/ar…
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If you are on UTSW campus May 16, please join us for the Lipid Metabolism & Neurodegenerative Disease mini-symposium! Many thanks to keynote speaker Dr. Hugo Bellen.
1 Apr 2025
Don’t miss out on the Lipid Metabolism and Neurodegenerative Diseases 2025 Mini Symposium! Check out the agenda below for the full details ⬇️
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25 Mar 2025
Reminder to join us tomorrow at 12pm ET
14 Mar 2025
Be sure to mark your calendars for March 26th at 12pm ET for the @AsbmbLrd seminar series. We have two great mitochondria-focused lipid talks planned from @JasonCasler1 from Laura Lackner's lab and Kailash Venkatraman from @ibudin's lab. Register here! events.zoom.us/ev/AqPwG5k03R…
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14 Mar 2025
Be sure to mark your calendars for March 26th at 12pm ET for the @AsbmbLrd seminar series. We have two great mitochondria-focused lipid talks planned from @JasonCasler1 from Laura Lackner's lab and Kailash Venkatraman from @ibudin's lab. Register here! events.zoom.us/ev/AqPwG5k03R…
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Jonathan Friedman retweeted
8 Mar 2025
For #teamtomo, context is everything.
We highlight the power of #surfacemorphometrics in guiding STA and quantitatively assessing the impact of these structures on the local environment.
@benjaminbarad
6 Mar 2025
Ya-Ting Chang, @nani_grotjahn et al. @scrippsresearch present a membrane-guided approach for identifying a subset of cytoplasmic #ribosomes oriented for protein import on the surface of #mitochondria in budding yeast using #cryoET hubs.la/Q039KqS80
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Happy to announce I am serving as Director of the Lipid Metabolism & Neurodegenerative Diseases (LMND) Program at UTSW. Our goal is to stimulate collaborations bridging lipid metabolism & neurological disease.
So proud of our lab & their cell biology adventures! #onward_science
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Jonathan Friedman retweeted
24 Dec 2024
Edington et al. @labfriedman @UTSWMedCenter identify a mitochondrial inner membrane protein that marks and facilitates a subset of sites of mitochondrial fission in human cells. hubs.la/Q030B0yQ0
#Organelles #Mitochondria
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24 Dec 2024
Looking for some holiday reading material? Our latest paper identifying a new player in mitochondrial fission is now out @JCellBiol! A wonderful early present to see this now online!
rupress.org/jcb/article/224/…
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9 Dec 2024
As you're planning out your ASCB schedule be sure to attend the organelle-focused special interest group hosted by @nieminm and myself Mon. 12/16 at 5pm
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3 Dec 2024
Honored and excited to present some of our latest work as part of this session!
3 Dec 2024
Join JCB Session 🗓️ Sat. December 14 11:15am at #CellBio2024! @s__ellis, @LabFriedman, @Meng2Fu, @BinyamMogessie, & Andrew Muroyama will discuss how new techniques in cell biology are revealing insights into how cells function across different scales. 👉 hubs.la/Q02Z5M2Q0
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12 Nov 2024
Be sure to check out @MitOtalks Thursday (10am US central time) for a double feature, including our amazing student Alia @TheMitotracker who will be presenting her work identifying a new player in mitochondrial fission! You can find a zoom link at mitotalks.org
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