Joined September 2010
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Whole Genome Sequencing [WGS] Reveals Novel, Clinically Relevant Biomarkers Missed by Standards of Care for Pts w/ Myelodysplastic Syndrome [MDS] [Jun 11, 2026] @AlexBataller et al. #EHA2026 EHA-4897 PF656 library.ehaweb.org/eha/2026/… #MDSsm #leusm #cagenome @UTMDAnderson @TempusAI
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Mike Thompson, MD, PhD, FASCO retweeted
Looking forward to hear Dr. Omar Nadeem’s from @DanaFarber updating the ImmunoPRISM tec SMM study later this morning at #EHA26 #EHA2026 #mmsm @IrenemGhobrial
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Mike Thompson, MD, PhD, FASCO retweeted
MajesTEC-9 at #EHA26 #EHA2026 #mmsm
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Mike Thompson, MD, PhD, FASCO retweeted
Not a plateau in whole cohort, but do the authors have info about MRD -ve VS. ve? Probably there we can see a plateau. @RahulBanerjeeMD
#EHA2026 not a plateau, but what amazing results all the same! @szusmani presenting updated CEPHEUS data. 6 years out for some patients, median OS *still* not reached with D-VRd despite no transplant. Great to see long-term quad data emerging!
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Mike Thompson, MD, PhD, FASCO retweeted
👉👉👉Sending a huge shout out to .@MyelomaTeacher - thanks for her wonderful patient advocacy in our field! We appreciate you so much ! Keep up your great work ! #EHA26 #EHA2026 @EHA_Hematology @HealthTree | #mmsm #MPNSM #BPDCN | 🙏 @mtmdphd for bringing us together!
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Mike Thompson, MD, PhD, FASCO retweeted
Replying to @szusmani
@szusmani presenting CEPHEUS TIE Final analysis #EHA26 #EHA2026 #mmsm
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Mike Thompson, MD, PhD, FASCO retweeted
#mmsm #EHA26 MajesTEC-4 Amazing data ✅ ≥CR was achieved in nearly 100% of patients across all 3 cohorts (100%, 96.9%, and 96.7%), up from roughly 41–60% post-ASCT ✅ Median PFS was not reached in any cohort. Estimated 18- and 24-month PFS rates were 94–97% Only 3 progression events across all 94 patients 👏 ✅ Grade 3/4 infections were lowest in the Tec Q4W monotherapy cohort (27%) vs. ~35–38% in the combination arms Beginning of an era of “no Lenalidomide maintenance and time limited BCMA maintenance Teclistimab continues to be impressive addition to the myeloma treatments
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Mike Thompson, MD, PhD, FASCO retweeted
Dr. Niels van de Donk updating MajesTEC-4 at #EHA26 #EHA2026 #mmsm
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Mike Thompson, MD, PhD, FASCO retweeted
Dr. Cyril’s Touzeau updating MajesTEC-9 at #EHA26 #EHA2026 #mmsm
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Mike Thompson, MD, PhD, FASCO retweeted
🚨 MonumenTAL-3 #EHA2026 Talquetamab moves earlier in RRMM Phase 3 MonumenTAL3 met its primary endpoint, showing significant PFS improvement versus DPd in patients with relapsed/refractory multiple myeloma after ≥1 prior line #mmsm
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Mike Thompson, MD, PhD, FASCO retweeted
CONGRESS | #EHA2026 | POSTER Naveen Pemmaraju shares real-world findings from a retrospective cohort study evaluating the treatment patterns and outcomes of pacritinib in patients with #myelofibrosis stratified by platelet (PLT) counts (N = 168). Category 1 reduction in spleen size was observed in 62% and 71% of patients with PLT <50x109/L and ≥50x109/L, respectively. SLR≥25 was achieved by 82% and 83% of patients in the PLT <50x109/L and ≥50x109/L groups, while SLR≥50 was achieved by 41% and 25%, respectively. Median hemoglobin increased by 0.6 g/dL and 0.8 g/dL by Day 180 in patients with PLT <50x109/L and ≥50x109/L, respectively. Both groups showed a reduction in MF-related symptoms through Day 180. The findings highlight the potential of pacritinib in treating patients with MF with and without severe thrombocytopenia. Follow our live feed for more updates: loom.ly/N2uNnTk Intended for HCPs only. This congress coverage is independently supported by pharmaceutical companies, who are allowed no influence on the content. a full list of supporters can be found on our website. #MPN #MPNsm #MedicalCongress @doctorpemm @UTMDAnderson
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Mike Thompson, MD, PhD, FASCO retweeted
#EHA2026 matching pink! GPRC5D bsAbs took the limelight today, but looking forward to @SusanBal9 teaching us about GPRC5D CAR-T tomorrow!
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Mike Thompson, MD, PhD, FASCO retweeted
#EHA2026 not a plateau, but what amazing results all the same! @szusmani presenting updated CEPHEUS data. 6 years out for some patients, median OS *still* not reached with D-VRd despite no transplant. Great to see long-term quad data emerging!
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Mike Thompson, MD, PhD, FASCO retweeted
CONGRESS | #EHA2026 | PRESENTATION Cyrille Touzeau presents results from the phase III MajesTEC-9 study evaluating teclistamab monotherapy versus pomalidomide, bortezomib, and dexamethasone (PVd) or carfilzomib and dexamethasone (Kd) in patients with RRMM. After a median follow-up of 17.3 months, median PFS was not reached with teclistamab versus 8.2 months with PVd/Kd (HR, 0.29; p < 0.0001). ORR was higher with teclistamab versus PVd/Kd (OR, 4.62; p < 0.0001). OS also favored teclistamab (HR, 0.60; p = 0.002). Infection rates were higher with teclistamab, including grade 5 infections (5.5% vs 2.8% with PVd/Kd). Follow our live feed for more updates: loom.ly/CXccZxs Intended for HCPs only. This congress coverage is independently supported by pharmaceutical companies, who are allowed no influence on the content; a full list of supporters can be found on our website. #MultipleMyeloma #myeloma #mmsm #MedEd @CHUnantes
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DDX41 germline predisposition - Sébert #EHA2026 #MDSsm #leusm #geneticcounselors penetrance - Villy et al. 2025
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Gender differences in risk over time. ~Perimenopause women risk somewhat plateaus. Hormone related? Modulating risk? #EHA2026 #MDSsm #geneticcounselors DDX41
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Answering myself — Dr. Sébert answered later that hormone differences are possible but data not available for women or men.
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Mike Thompson, MD, PhD, FASCO retweeted
#EHA2026 #EHA26 #mdssm #poster_presentation #TP53-Mutated MDS: The CCR5 Axis as a Driver of T-Cell Exhaustion #TP53-mutated MDS exhibits a distinct exhausted T-cell phenotype with increased immune checkpoint expression. 🔹 Single-cell analyses identified activation of the CCR5 signaling axis as a key driver of T-cell dysfunction and immune escape.
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Mike Thompson, MD, PhD, FASCO retweeted
#EHA2026 and congrats #cyrilletouzeau and the whole MajesTEC-9 team for such excellent results! Tec monotherapy joins our growing landscape of excellent treatment options as early as first relapse 👏
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Mike Thompson, MD, PhD, FASCO retweeted
🙌 Delighted to be a part of our rapidly growing international MPN research community ! A wonderful, collegial group! @doctorpemm @Vikas_Gupta_1 @Barbara_MoraMD @sk_tantravahi | #MPNSM
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Somatic mutations as predictors of blast crisis #EHA26
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