The National Center for Genome Analysis Support is a publicly-funded institution dedicated to providing help for biologists who require intensive computation.
We've (including @thesteinegger @milot_mirdita ) updated ColabFold to use the latest optimized AlphaFold implementation that reduces compile time from ~4.5mins to ~30 seconds! We've confirmed the results are identical for both monomer and multimer predictions. Try it out! (1/2)
A Review published in @NatureRevMicro explores the diverse functions of CRISPR–Cas systems beyond adaptive immunity and discusses its implications on the development of CRISPR-based genome editing applications. go.nature.com/3zFfcsO
DNA origami is a great activity to do with your family over the holidays! Who says DNA isn’t festive? My origami here looks unique… just like everyone’s DNA! Find a printable form for this DNA origami and instructions here: go.usa.gov/xeM4A
Citizen science can contribute HEAPS of quality data. @FrogIDAus is now up to ~440,000 expert-validated frog records in <4yrs. And look at this quality call recording from FrogID - one of many being used in bioacoustics research.
Perfect timing for the peer-reviewed pub... we're having our students use Trycycler during a semester-long Microbial Genomics course. Excellent work @rrwick and co!
Trycycler. from @rrwick, @DrKatHolt & co, generates a consensus assembly from multiple input assemblies from long read sequencing of bacterial genomes. Errors are generally in a single assembly, so get averaged out. Polishing can improve the assembly more. genomebiology.biomedcentral.…
ALT Improvement of genomes with Trycycler, relative to other assemblers
Some of the best resources I came across for intuitively visualizing #NeuralNetworks (how they transform data and classify stuff).
With these resources, Neural Networks will be no longer black boxes for you'll.
A thread 🧵
Really excited to unveil sandbox.bio, an interactive playground for learning bioinformatics command-line tools like bedtools, bowtie2, and samtools (and more to come!) 🧑💻 🧬
Thanks to @aaronquinlan, @BenLangmead, and @mike_schatz for feedback and tutorial ideas.