Check out our YC launch!

Today, we're excited to release 10,000 fully AI-designed enhancer sequences for the research community. Axis was prompted to design sequences with targeted activity in one of three widely used cell-lines. AI allows us to explore a vast design space, going beyond the natural genome.

Muon can accelerate LLM training, but does that benefit transfer to regulatory DNA sequence modeling with its different data distribution? 🧬 Our results show that Muon with independent weight decay (MuonW) hits our validation perplexity target in ~37% fewer FLOPs than the best Adam configuration.

It was an honor to meet PM @narendramodi and discuss the potential impact of the work we are doing at @origin_bio

Cell and gene therapies have the potential to offer a much higher quality of life to patients. Getting transcriptional control right is going to unlock a whole new class of them. Happy to share a small preview into Axis’ ability to design novel regulatory DNA sequences. It’s so obvious that evolution has only explored a drop in the whole ocean. Now finally with AI can we start to take a deep dive.

We're still in the early days of durable and long lasting drugs based on transcriptional control - similar to where mRNA medicines were many years ago! With AI designed regulatory DNA and millions of sequences we're lab testing, we aim to precisely program gene expression @origin_bio

Origin (@origin_bio) is using AI to make safer cell & gene therapies for diseases like cancer. Their model designs DNA switches & dials to program precise gene expression patterns in disease cells. Congrats on the launch @YashRathod_75 and @malhar317! ycombinator.com/launches/PMG…

Going on TBPN at 1:45 pm PT to launch @origin_bio and our model, Axis. Axis is the first model that generates regulatory DNA sequences and predicts its function. Axis already outperforms DeepMind's AlphaGenome on various benchmarks!