Computational biologist
Joined March 2013
- Tweets 32
- Following 53
- Followers 41
- Likes 76
1 Photos and videos
Salmonella Outbreak: 68 people are sick in 19 states, with 18 hospitalizations.
Check your home for recalled whole fresh American cucumbers. Do not eat recalled products and throw them away.
bit.ly/4eNjGR6
ALT Whole fresh American cucumbers with text saying: Salmonella outbreak linked to recalled cucumbers. Whole fresh American cucumbers. • From “Agrotato, S.A. de C.V.” a grower in Mexico • All sizes packaged in bulk cardboard containers for retail or food service • Were sold between October 12, 2024, and November 26, 2024 • Look for a “SunFed Mexico” sticker cdc.gov/foodborne-outbreaks.
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Nagarajan Raju retweeted
19 Sep 2024
IgG3 #antibodies with exceptional breadth of virus cross-reactivity, with no signs of autoreactivity.
Work led by Dr. Matt Vukovich, in collaboration with the groups of @PriyamvadaA_Lab, Giuseppe Sautto, @DannySheward, and others.
dx.plos.org/10.1371/journal.…
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Nagarajan Raju retweeted
15 Jul 2024
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Nagarajan Raju retweeted
15 May 2024
Immense pleasure to share that I have been honoured as a ScholarGPS Highly Ranked Scholar (#8) in Bioinformatics. @iitmadras @iitmbt @PBI_Lab.
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Nagarajan Raju retweeted
25 Mar 2024
Nature creates amazing #antibodies, but finding the right ones for any given target is a huge challenge. This paper presents a small but important proof of concept for using #AI to design human antibodies against #antigens of interest (here, #SARSCoV2).
biorxiv.org/content/10.1101/…
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Nagarajan Raju retweeted
16 Mar 2024
A public VH-based class of ultra-potent hPIV3-neutralizing #antibodies. Work led by soon-to-be Dr. Alexandra Abu-Shmais from our group, in collab with the labs of @jjmousa, @RHCarnahan, @croweje.
journals.aai.org/jimmunol/ar…
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Wonderful work. Happy to be a part of this project.
29 Feb 2024
Excited to share our latest work on the CARD8 #inflammasome in #HIV/SIV pathogenesis and disease progression @CellCellPress Our study suggests that CARD8 drives CD4 T cell depletion during
HIV infection. cell.com/cell/fulltext/S0092…
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Nagarajan Raju retweeted
13 Dec 2023
This paper, led by Ph.D. candidate Matt Vukovich, is now published in @ASMicrobiology Journal of Virology: journals.asm.org/doi/10.1128…
29 Sep 2023
It is hard enough to design #HIV #vaccines that elicit neutralizing #antibody responses that show some breadth of reactivity in animal models, but trying to deconvolute these responses at the single-cell level is yet another challenge.
biorxiv.org/content/10.1101/…
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Nagarajan Raju retweeted
8 Sep 2023
A large-scale #LIBRAseq atlas of #antibody-#antigen pairs sheds light on important questions underlying the relationship between antibody sequence and antigen specificity, and provides insights into population-level responses.
biorxiv.org/content/10.1101/…
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Nagarajan Raju retweeted
27 Jan 2023
SO excited to share this (hugely collaborative) study! @IG_lab
We discovered #HIV/#HepC cross-reactive #antibodies with broadly neutralizing and Fc-mediated anti-viral activity. Somatic hypermutation plays a critical role in developing this unique reactivity. ⬇️⬇️⬇️⬇️⬇️
27 Jan 2023
Functional HIV-1/HCV cross-reactive antibodies isolated from a chronically co-infected donor dlvr.it/ShXTjK
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Nagarajan Raju retweeted
16 Jun 2022
A big effort @VUMC_VCI @VUMC_Vaccines with 3x1st authors Kevin Kramer @DoctorKvoss Erin Wilfong and 4 senior @jonathanirish @IG_lab @BonamiRachel to find the B and T cells that drive COVID vaccine response, poor responders & a breakthrough
nature.com/articles/s41467-0…
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Nagarajan Raju retweeted
3 Mar 2022
#LIBRAseq with ligand blocking enables targeted discovery of functional (not just binding) #antibodies.
Double #ACE2-blockers for both #SARSCoV2 and #SARSCoV were also identified.
Easily generalizable for #mAb discovery aiming to block other types of antigen-ligand interactions
3 Mar 2022
Efficient discovery of SARS-CoV-2-neutralizing antibodies via B cell receptor sequencing and ligand blocking go.nature.com/35O9Ali
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Nagarajan Raju retweeted
9 Nov 2021
We have a postdoctoral opening in antibody discovery, with a special emphasis on the development and application of innovative #bioinformatics technologies.
Come do cutting-edge research in #antibody and #vaccine science in #Nashville, one of the hottest destinations in the US!
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Nagarajan Raju retweeted
29 Jul 2021
Great collaborative work with lots of cool findings, including #LIBRAseq characterization of the evolution of B cell antigen specificity at the single-cell level from before to after #SARSCoV2 vaccination.
28 Jul 2021
Single-Cell Profiling of the Antigen-Specific Response to BNT162b2 SARS-CoV-2 RNA Vaccine biorxiv.org/content/10.1101/…
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Nagarajan Raju retweeted
3 Jun 2021
With next-generation #LIBRAseq, there is no need to test hundreds to thousands of candidates in order to identify potent functional #antibodies.
biorxiv.org/content/10.1101/…
Efficient discovery of potently neutralizing #SARSCoV2 antibodies using LIBRA-seq with ligand blocking.
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Nagarajan Raju retweeted
21 May 2021
First in-person lab meeting since the start of Covid shutdowns. Today truly was a great day in the IG lab ❤️
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Nagarajan Raju retweeted
20 May 2021
Additional critical contributions by @rnrbio and collaborators, building on work by @IanSetliff.
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