Crazy planetary alignment tonight. That's Jupiter and Venus. It looks like a pair of celestial eyes, staring back at you.

Nothing quantum fluctuations -> Random somethings Random somethings together -> Emergent order Ordered reality 2nd law -> More entropy Total entropy ≈> nothing ¯\_(ツ)_/¯

I just sequenced a human genome to 30× coverage entirely at home. As far as I know, this is the first time this has been done. I didn’t step foot in a lab once. Every step - from saliva collection, to running the sequencer - took place in a single room with a dining table kitchenette. Six weeks ago, I had never done wet lab biology before. I used an Oxford Nanopore P2 Solo - the only commercially available sequencing device portable enough to do 30x human genome sequencing at home. Biggest takeaway - I could build something that combined software, hardware, and molecular biology far faster than I thought was possible. I can name >100 specific instances where AI helped me solve a technical problem that would previously have blocked me because I lacked access to a domain expert. For example: how do I save my sequencing run when my DNA extraction yield is 4x lower than I need it to be, and I have this limited set of reagents to hand? To make this work, I had to navigate multiple disciplines: - writing software to monitor sequencing runs and orchestrate remote GPU infra for basecalling - learning executing 5 hour long molecular biology protocols - building a hardware device to quantify DNA concentration Apologies for the hyperbole, but I feel super lucky to be living in 2026. A few weeks ago I decided to sequence a human genome to 30x at home. Then I actually did it. And I did it really quickly.

The RF world is insane. Researchers recovered AES-128 keys from a Bluetooth chip by listening to its own antenna from 10 meters away. Crypto-engine switching noise couples into the RF chain, rides the 2.4 GHz carrier, and leaks out as radio.

Massive police action shutting down the Bay Bridge heading Eastbound.

Interesting take. Does Mythos change the economics of software vulnerability research? Perhaps not, but it does raise again the opportunity to remake the open source software landscape in a way that gets developers paid.

My dear front-end developers (and anyone who’s interested in the future of interfaces): I have crawled through depths of hell to bring you, for the foreseeable years, one of the more important foundational pieces of UI engineering (if not in implementation then certainly at least in concept): Fast, accurate and comprehensive userland text measurement algorithm in pure TypeScript, usable for laying out entire web pages without CSS, bypassing DOM measurements and reflow

Can you solve this? Prove you are smarter than AI. You are. Today, ChatGPT 5.2 Thinking, Gemini 3 Pro, and Opus 4.6 all FAILED. 🤖 ChatGPT 5.2 Thinking said 70° 🤖 Gemini 3 Pro said 100° 🤖 Opus 4.6 said 80° One was correct, but it's logic was based on an imagined quadrilateral. Put your answer below. Go on! You can do it. There is no question that all these LLM based tools are amazing. Anthropic's Opus 4.6 is great for writing code. But none of the GPTs solved this basic challenge correctly. Parts of inference, logic, and most of causality are still missing.

🚨 This paper just murdered the foundation of every AI model you've ever used. A researcher proved you can match Transformer performance WITHOUT computing a single attention weight. Here's what changed (and why this matters now):

Did you know some call the night before Thanksgiving "Blackout Wednesday? It's the 2nd deadliest night of the year for drunk driving. Here's another way

𝗤𝘂𝗮𝗻𝘁𝘂𝗺 𝗧𝗿𝘆𝗽𝘁𝗼𝗽𝗵𝗮𝗻 𝗘𝗺𝗲𝗿𝗴𝗲𝗻𝘁 𝗕𝗲𝗵𝗮𝘃𝗶𝗼𝗿 𝗶𝗻 𝗠𝗶𝗰𝗿𝗼𝘁𝘂𝗯𝘂𝗹𝗲𝘀 𝗣𝘁.𝟭 This fascinating video, presented at the GRS/GRC – Quantum Biology Conference 2025, offers an artistic visualization of a hypothesized quantum tryptophan emergent behavior in microtubules. The concept is imaginative but remains unverified, meaning it’s an open hypothesis awaiting future scientific exploration. At the time of the video’s release, this quantum tryptophan behavior is not proven and should be seen as a creative idea rather than a confirmed fact. Scientists still need to conduct experiments to either support or disprove this intriguing possibility. The video suggests that this proposed quantum behavior happens on incredibly fast timescales, ranging from picoseconds to femtoseconds. This speed sets it apart from other processes, making it a unique subject of study in quantum biology. Unlike quantum computing, which relies on long-lasting coherence, this phenomenon is entirely different and should not be confused with it. Instead, it represents a distinct kind of quantum event that doesn’t follow the rules of typical computational systems. The visualization ties this behavior to non-computable problems, meaning it’s more about mysterious, unsolvable questions than traditional computing. This makes it an exciting opposite to conventional computation, opening new doors in quantum biology research. This clip is from "𝗤𝘂𝗮𝗻𝘁𝘂𝗺 𝗧𝗿𝘆𝗽𝘁𝗼𝗽𝗵𝗮𝗻 𝗘𝗺𝗲𝗿𝗴𝗲𝗻𝘁 𝗕𝗲𝗵𝗮𝘃𝗶𝗼𝘂𝗿 𝗶𝗻 𝗠𝗶𝗰𝗿𝗼𝘁𝘂𝗯𝘂𝗹𝗲𝘀 - 𝗔𝗿𝘁𝗶𝘀𝘁𝗶𝗰 𝗩𝗶𝘀𝘂𝗮𝗹𝗶𝘇𝗮𝘁𝗶𝗼𝗻" (The Scientist Makes Art, YouTube, Mar 10, 2025) at 00:29 Made with 𝗳𝗮𝘀𝘁𝗰𝗹𝗶𝗽 dot 𝗶𝘁 - create and publish clips from videos extremely fast (<60 seconds from start to finish)

Faster payments means faster fraud. Reported rates up 25% YoY. Led by investment scams. Fraud is growing faster than the S&P, Nasdaq or almost any other asset class. This is a plague on retirees and all of society. AI-Generated Scams Instant Payments built without baked-in fraud controls is a nightmare. The solutions are known, but it takes industry coordination on things like - UI Solutions that should be a default, like step up verification if a high risk of a scam is detected. Cool down periods, or direct 1:1 calls with the customer via a secure channel like the mobile app. - Scam best practice sharing (working with UK Fintech companies and banks on this, there's also an initiative by the The Aspen Institute) - Scam early warning signs, like screenshot detection, calls in session. - Data sharing (like Sonar or Plaid's Beacon). h/t @mikulaja for spotting this

This is Oakland, California

This might explain the broad adoption of certain languages. As English and French and Mandarin grew and evolved and incorporated more words, the languages came to be able to convey more information as measured in bits per second.

Amazing graphical representation of a neural net, never seen anything like it.

Great example of the primary reason for California's limited rainfall. You can clearly see the presence of a semi-permanent high pressure system off the coast. This system, known as the North Pacific High, sits off the California coast for about 6 to 8 months of the year. It acts as a barrier, redirecting incoming storms northward to Oregon, Washington, and British Columbia, or southward to central/southern Mexico and Central America.

"The AI Investment Boom" - Excellent analysis from @JosephPolitano about the "historical scale of current investments" being made U.S. private sector in AI R&D. Some absolutely astonishing numbers in here. (HT: @binarybits) apricitas.io/p/the-ai-invest…

What if you could make physics diagrams come alive? At #UIST2024, we will be presenting our paper, Augmented Physics, an ML-Integrated Authoring Tool for Creating Interactive Physics Simulations from Static Diagrams Co-authors: @Freya_Wyy @nandizhang_ Jarin @rubaiat @ryosuzk

If this works, our collective future will be very bright.