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Jensen Lab @theJensenLab

This is the official Twitter feed of the Jensen Lab @BYU

Joined October 2014
  • Tweets 207
  • Following 774
  • Followers 4,122
121 Photos and videos
Shoutout to Phyllis and her work on human NLRP3 inflammasomes! Great to see this published.
Phyllis Wang@Phyllis23382012
Mar 27
A big part of my graduate work has finally made it online. Proof that science loves to surprise us in experiments😎 @theJensenLab Human NLRP3 inflammasome activation leads to formation of condensate at the microtubule organizing center | Science Advances science.org/doi/10.1126/scia…
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Check out our @JoVEJournal video article with @Phyllis23382012 describing how to use a new tri-coincident fluorescence, electron, and ion beam microscope for targeted milling of cells! Full video & article: hubs.ly/Q047QRRK0 #JoVE #Reproducibility
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Producing lamellae containing small and rare fluorescent targets is getting more efficient: app.jove.com/t/68238/workflo…
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Our lab collaborated with @BYU_Biophysics to create this important tomogram dataset, which will be a useful benchmark for future machine learning developments in the cryo-ET world.
BYU_BiophysicsGroup@BYU_Biophysics
29 Apr 2025
Excited to share our paper about MotorBench, the dataset we created for our ongoing #Kaggle competition, posted on BioRxiv: biorxiv.org/content/10.1101/…
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Jensen Lab retweeted
PNCC@CryoEM_PNCC
10 Apr 2025
Please join us at #MM2025 for our jointly hosted Pre-Meeting Congress (PMCX61) on Transformative High-Resolution CryoEM! Let's shape the future of microscopy & structural biology research. We look forward to seeing you there. #CryoEM
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Join me at the Structure-Based Drug Design Summit, where I'll be leading a discussion-based workshop on the potential of cryo-ET for structure-based drug design. Learn more here: ter.li/rpnj5g
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Our lab provided tomography data for this exciting competition, which aims to accelerate the cryo-ET workflow. If you're skilled with AI and machine learning development, please participate!
BYU_BiophysicsGroup@BYU_Biophysics
6 Mar 2025
Interested in helping solve a machine learning problem for structural biologists (and competing for a cash prize)? Check out our @kaggle competition that launched yesterday: kaggle.com/competitions/byu-… We look forward to seeing your submissions!
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It’s been a while, but we’re getting back up and running at BYU. In case you missed them, here’s a thread with a few of the papers we’ve worked on in the meantime. Congrats to all authors, and full steam ahead!
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doi.org/10.7554/eLife.82891 in @eLife

A cryogenic, coincident fluorescence, electron, and ion beam microscope

Integrating a cryogenic light microscope with a focused ion beam/scanning electron microscope, allows directly targeting of fluorescent structure when preparing a frozen-hydrated lamella, without the...

elifesciences.org
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doi.org/10.1016/j.str.2023.0… in @Structure_CP
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biorxiv.org/content/10.1101/… at @biorxivpreprint

Structure and Function of the Dot/Icm T4SS

The Legionella pneumophila Dot/Icm type IV secretion system (T4SS) delivers effector proteins into host cells during infection. Despite its significance as a potential drug target, our current...

biorxiv.org
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doi.org/10.1038/s41564-023-0… in @NatureMicrobiol
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Check out our new paper in @JStructBiol X on a subtomogram averaging workflow to capture structures and their molecular context: doi.org/10.1016/j.yjsbx.2022… Congrats to @LAMetskas and all authors!
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Our paper with @mikhailshapiro and Michael Ortiz groups on buckling properties of bacterial gas vesicles out now in @BiophysJ: doi.org/10.1016/j.bpj.2022.0… Congrats to (Amir) Hossein Salahshoor, @yuxing_yao, @przemyslawdutka and all authors!
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Check out our new @biorxivpreprint with @DebnathGhosal, @ElitzaTocheva, and Anath Das groups on the structure of the Agrobacterium tumefaciens T-pilus: doi.org/10.1101/2022.09.25.5… Congrats to Stefan Kreida, Akihiro Narita and all authors!
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Check out our new @biorxivpreprint with @DebnathGhosal, Robert Heinzen's groups and others on structural remodeling of Coxiella burnetii during its biphasic developmental cycle: doi.org/10.1101/2022.08.23.5… Congrats to @MohammedKaplan_, @DoulinShepherd and all authors!
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Our paper with @SavageCatsOnly on RuBisCO lattices in α-carboxysomes is out now in @NatureComms: doi.org/10.1038/s41467-022-3… Congrats to @LAMetskas and all authors!
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Check out our collaboration with Anton Zavialov's group and others on the zigzag spring-like structure of an archaic chaperone-usher pilus in @Nature: doi.org/10.1038/s41586-022-0… Congrats to @NPakharuk, Henri Malmi and all authors!
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Our paper with @CLShafferPhD, @sigalby and @IlanRosenshine labs on a novel and widespread bacterial structure related to the type III secretion system is out now in @JBacteriology: doi.org/10.1128/jb.00144-22 Congrats to @MohammedKaplan_ and all authors!
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...and now a link! doi.org/10.1101/2022.06.27.4…

Jensen Lab@theJensenLab
30 Jun 2022
Check out our new @biorxivpreprint with @mikhailshapiro's and Michael Ortiz's groups on buckling properties of different bacterial gas vesicle geometries. Congrats to (Amir) Hossein Salahshoor, @yuxing_yao, @przemyslawdutka and all authors!
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