Theory lab at SISSA / Trieste. Interested in stochastic processes in biology & biophysics. @zechnerlab.bsky.social

Joined March 2017
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Exciting news! As of today, our group is part of SISSA in Trieste. Big THANK YOU to all current and past group members, collaborators and mentors and to @mpicbg for hosting us for 8 amazing years! If you are interested in joining us in Trieste, please get in touch! @Sissaschool
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Zechner lab retweeted
Very happy to share the first article from my postdoc work in the Tomancak lab! biorxiv.org/content/10.1101/…. We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)
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Tommaso's paper on approximating moments of stochastic multiscale models is now out in Math Biosci! Fantastic job by @churli ! @csbdresden @mpicbg sciencedirect.com/science/ar…

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The new method is integrated into our symbolic moment generator Compartor, which is available on GitHub: github.com/zechnerlab/compar…
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Zechner lab retweeted
This is now up @BiophysJ! Getting lipid signaling kinetic parameters from single-cell data with @MLennartz1 @PavelBarahtjan @looneycoons11 @JManuel9112 @zechnerlab @nadlerlab @MMSchuhmacher 😀😊 Read here! doi.org/10.1016/j.bpj.2023.1…
Together with the @zechnerlab we have pushed live-cell quantitative lipid biochemistry to the single cell level. It works - but some lipids are weird. 🤓 Great effort by shared 1st authors @davidtgonzales1 and @MMSchuhmacher. Let us know what you think! biorxiv.org/content/10.1101/…
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Zechner lab retweeted
Cover image @ChemSystemsChem featuring our synthetic cell communities doi.org/10.1002/syst.2023000… 😀 @DoraTang5 @zechnerlab @mpicbg
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19 Oct 2023
Two great talks from Tarun Mascarenhas and Anne-Lena Moor from Zechner lab on information transfer during ⁦@centuri_ls⁩ conference in Cargese. Very interesting. 😊
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16 Aug 2023
Its out! We integrate Cell‐Free Quorum Sensing Gene Circuits into Droplet Interface Bilayers. A great platform for bio-inspired bidirectional communication. Beautiful work @gonzalesdavid in collaboration with @zechnerlab! See it here.... chemistry-europe.onlinelibra…
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Zechner lab retweeted
How do distant DNA loci come into contact to activate genes? Our paper combining live imaging 🔬& polymer physics 🧬 to answer this is out in @ScienceMagazine! We show how chromosome packing & diffusion determine pairwise dynamics & transcription 👉science.org/doi/10.1126/scie… 1/n
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Very proud to share that former group member @LorenzoDuso was awarded the Otto-Hahn Medal for his outstanding PhD thesis @csbdresden @mpicbg Many congratulations for this exceptional achievement! Image: © David Ausserhofer / Max-Planck-Gesellschaft
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Congrats David!!
Our preprint on building a bottom-up synthetic multicellular community is up! 😄 biorxiv.org/content/10.1101/… See how we use cell-free expression of quorum sensing gene circuits in DIBs to make synthetic cells that communicate and have feedback loops! @DoraTang5 @zechnerlab @mpicbg
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Zechner lab retweeted
Together with the @zechnerlab we have pushed live-cell quantitative lipid biochemistry to the single cell level. It works - but some lipids are weird. 🤓 Great effort by shared 1st authors @davidtgonzales1 and @MMSchuhmacher. Let us know what you think! biorxiv.org/content/10.1101/…
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Zechner lab retweeted
Thanks @Dmichiel1 @wendy_bickmore for highlighting in @MolecularCell cell.com/molecular-cell/full… our recent work science.org/doi/full/10.1126… visualizing a TAD-forming CTCF/cohesin loop in live cells and showing these structures to be dynamic, rare, and largely partially extruded.
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Next up @davidtgonzales1!! Wonderful example of a multidisciplinary PhD project, combining both experiment and theory. Many congratulations to your graduation David!! @tanglab @mpicbg @csbdresden @imprs_mpicbg
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Huge congratulations to @FOltsch for his outstanding PhD defense last week! Many thanks for all the great work & fun and best of luck for your future adventures! @imprs_mpicbg @csbdresden @mpicbg
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Zechner lab retweeted
A thing to copy is @mpicbg tutorial with PhD students and ECRs before a seminar. I had a great time with these outstanding scientists. Many thanks to @zechnerlab for the invitation and discussions. Near-zero carbon footprint and no jetlag added bonus.
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