Science & Technology Advances in Human Reproduction. #Reproduction #Science #Technology #Research #News

Joined September 2022
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Both insufficient and excessive sleep are associated with accelerated aging in nearly every organ system. @Nature
Both short sleep (fewer than 6 hours) and long sleep (greater than 8 hours) correlate with faster biological aging. @Nature
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Two New Papers 🚩Rethinking ultra-processed foods: Controversies, health evidence, and policy directions #TheInnovationNutrition 🚩Ultraprocessed foods and obesity: Interpreting the evidence @ScienceMagazine
Rethinking ultra-processed foods: Controversies, health evidence, and policy directions doi.org/10.59717/j.xinn-nutr… Ultraprocessed foods and obesity: Interpreting the evidence @ScienceMagazine science.org/doi/10.1126/scie…
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Better than Science? 🚩Rethinking ultra-processed foods: Controversies, health evidence, and policy directions #TheInnovationNutrition 🚩Ultraprocessed foods and obesity: Interpreting the evidence @ScienceMagazine
Rethinking ultra-processed foods: Controversies, health evidence, and policy directions doi.org/10.59717/j.xinn-nutr… Ultraprocessed foods and obesity: Interpreting the evidence @ScienceMagazine science.org/doi/10.1126/scie…
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Rethinking ultra-processed foods: Controversies, health evidence, and policy directions doi.org/10.59717/j.xinn-nutr… Ultraprocessed foods and obesity: Interpreting the evidence @ScienceMagazine science.org/doi/10.1126/scie…
Revisiting computational immunogenicity prediction for novel food ingredients Open Access the-innovation.org/article/d…
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Detecting lung cancer 5 years before it happens @CellCellPress @CharlesSwanton
Artificial intelligence detects breast cancer 5 years before it develops #MedEd #MedTwitter #SCIENCE #technology #oncology #Cancer #Diagnosis
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A 14-protein plasma signature predicts lung cancer more than 5 years before diagnosis @CellCellPress @CharlesSwanton
Detecting lung cancer 5 years before it happens @CellCellPress @CharlesSwanton
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Fasting-mimicking diet offers new ways for crohn’s diseases management Open Access the-innovation.org/article/d…
INAUGURATION   The Innovation Nutrition: An international journal of nutrition science Open Access the-innovation.org/article/d…
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The Innovation Nutrition: An international journal of nutrition science Open Access the-innovation.org/the-innov…
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INAUGURATION   The Innovation Nutrition: An international journal of nutrition science Open Access the-innovation.org/article/d…
The Innovation Nutrition: An international journal of nutrition science Open Access the-innovation.org/the-innov…
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Revisiting computational immunogenicity prediction for novel food ingredients Open Access the-innovation.org/article/d…
The challenge of weight management: Looking beyond short-term solutions Open Access the-innovation.org/article/d…
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The challenge of weight management: Looking beyond short-term solutions Open Access the-innovation.org/article/d…
Fasting-mimicking diet offers new ways for crohn’s diseases management Open Access the-innovation.org/article/d…
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Time-restricted feeding extends healthspan in both sexes and lifespan in male @NatureAging
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Why we need a good mood before bed
Both short sleep (fewer than 6 hours) and long sleep (greater than 8 hours) correlate with faster biological aging. @Nature
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Tumor metabolism at the center of the cancer hallmarks. #ASCO26
Tumor Metabolism: The Central Integrating Node of the 2026 Cancer Hallmarks Open Access the-innovation.org/article/d… In January 2026, Douglas Hanahan updated the "Cancer Hallmarks" framework. Our recent commentary in The Innovation Nutrition argues that tumor metabolism is no longer just a classic hallmark, but the "universal language" linking all dimensions of cancer biology.  By positioning metabolic reprogramming at the center, we bridge FOUR critical dimensions:  1. Core Hallmarks: Metabolism fuels proliferation and facilitates immune evasion via lactate-mediated acidification.  2. Enabling Characteristics: It acts as a master conductor of epigenetic changes and is the "behind-the-scenes driver" of phenotypic plasticity.  3. Microenvironmental Cells: The TME functions as a metabolic ecosystem where cancer cells and stromal cells (like CAFs) engage in "metabolic collaboration".  4. Systemic Interactions: We highlight the emerging roles of neural regulation, the gut microbiome, and systemic conditions like cachexia in tumor progression.  This multidimensional perspective provides a theoretical foundation for "Hallmark-guided personalized therapy". By co-targeting metabolic nodes alongside other hallmarks, we can overcome therapy resistance and move toward true precision oncology. #Cancer #CancerResearch #metabolism #Hallmark #Science #ASCO26 #TumorEnvironment #metastasis #news #TME #oncology #CAFs
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Tumor Metabolism: The Central Integrating Node of the 2026 Cancer Hallmarks Open Access the-innovation.org/article/d… In January 2026, Douglas Hanahan updated the "Cancer Hallmarks" framework. Our recent commentary in The Innovation Nutrition argues that tumor metabolism is no longer just a classic hallmark, but the "universal language" linking all dimensions of cancer biology.  By positioning metabolic reprogramming at the center, we bridge FOUR critical dimensions:  1. Core Hallmarks: Metabolism fuels proliferation and facilitates immune evasion via lactate-mediated acidification.  2. Enabling Characteristics: It acts as a master conductor of epigenetic changes and is the "behind-the-scenes driver" of phenotypic plasticity.  3. Microenvironmental Cells: The TME functions as a metabolic ecosystem where cancer cells and stromal cells (like CAFs) engage in "metabolic collaboration".  4. Systemic Interactions: We highlight the emerging roles of neural regulation, the gut microbiome, and systemic conditions like cachexia in tumor progression.  This multidimensional perspective provides a theoretical foundation for "Hallmark-guided personalized therapy". By co-targeting metabolic nodes alongside other hallmarks, we can overcome therapy resistance and move toward true precision oncology. #Cancer #CancerResearch #metabolism #Hallmark #Science #ASCO26 #TumorEnvironment #metastasis #news #TME #oncology #CAFs
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Replying to @OncoAlert
ZEGFROVY® (sunvozertinib) monotherapy demonstrated superior anti-tumor efficacy, compared to platinum-doublet chemotherapy, in untreated NSCLC patients with EGFR exon 20 insertion mutations (exon20ins).
Phase 3 WU-KONG28 results for ZEGFROVY® demonstrate superior efficacy versus platinum-doublet chemotherapy in first-line EGFR exon20ins NSCLC. Featured as an #ASCO26 LBA and published in The NEJM. dizalpharma.com/news/detail?… #NSCLC #Oncology #EGFR #TKI #Exon20ins #LungCancer
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Presented at #ASCO26: In NSCLC with 𝘌𝘎𝘍𝘙 exon 20 insertions, first-line sunvozertinib led to longer progression-free survival than chemotherapy. The most common adverse events of grade 3 or higher were elevated creatine kinase, diarrhea, and anemia.
Phase 3 WU-KONG28 results for ZEGFROVY® demonstrate superior efficacy versus platinum-doublet chemotherapy in first-line EGFR exon20ins NSCLC. Featured as an #ASCO26 LBA and published in The NEJM. dizalpharma.com/news/detail?… #NSCLC #Oncology #EGFR #TKI #Exon20ins #LungCancer
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The efficacy of sunvozertinib was superior to that of chemotherapy as first-line treatment for advanced NSCLC with EGFR exon 20 insertions. @NEJM #ASCO26
Phase 3 WU-KONG28 results for ZEGFROVY® demonstrate superior efficacy versus platinum-doublet chemotherapy in first-line EGFR exon20ins NSCLC. Featured as an #ASCO26 LBA and published in The NEJM. dizalpharma.com/news/detail?… #NSCLC #Oncology #EGFR #TKI #Exon20ins #LungCancer
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Phase 3 WU-KONG28 results for ZEGFROVY® demonstrate superior efficacy versus platinum-doublet chemotherapy in first-line EGFR exon20ins NSCLC. Featured as an #ASCO26 LBA and published in The NEJM. dizalpharma.com/news/detail?… #NSCLC #Oncology #EGFR #TKI #Exon20ins #LungCancer
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Economic evaluation of pediatric clinical nutrition intervention: A real-world study from the national children's medical center Open Access doi.org/10.59717/j.xinn-nutr…
Economic evaluation of pediatric clinical nutrition intervention: A real-world study from the national children's medical center Open Access doi.org/10.59717/j.xinn-nutr… #Nutrition #economic #pediatrics #meded #medx
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Dizal Announces Phase 3 WU-KONG28 Results: ZEGFROVY®(Sunvozertinib) Outperforms Platinum-Doublet Chemotherapy in First-Line EGFR Exon 20 Insertion Mutation-Positive Non-Small Cell Lung Cancer. @NEJM #ASCO26 #Oncology #EGFR #Cancer #LungCancer #NSCLC
Phase 3 WU-KONG28 results for ZEGFROVY® demonstrate superior efficacy versus platinum-doublet chemotherapy in first-line EGFR exon20ins NSCLC. Featured as an #ASCO26 LBA and published in The NEJM. dizalpharma.com/news/detail?… #NSCLC #Oncology #EGFR #TKI #Exon20ins #LungCancer
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