Professor of Mathematical Biology at the University of Sheffield.
Joined November 2012
- Tweets 3,508
- Following 532
- Followers 1,469
- Likes 919
205 Photos and videos
Pinned Tweet
10 Nov 2022
🚨 2 math bio PhD projects available with me @shefmathbio @mathsatshefuni both close collaborations with experimental biologists! 1) Understanding tissue patterning in a fluctuating environment findaphd.com/search/ProjectD…
1
9
12
Alex Fletcher retweeted
🚨 New Preprint
"Quantification and statistical comparison of cell-state transition kinetics using a parametric failure-based model"
doi.org/10.64898/2026.04.21.…
Cells do not usually change state at a single fixed time.
How can we compare these distributions across conditions?
🧵1/3
1
2
9
626
18 Nov 2025
Exciting interdisciplinary PhD opportunities in Sheffield:
Investigating developmental failure and success: tiny.cc/rw7v001
Cellular mechanisms of CO-induced metabolic stress: tiny.cc/ww7v001
Evolution of a GRN underlying avian flight: tiny.cc/1x7v001
2
1
251
Alex Fletcher retweeted
3 Nov 2025
🚨 Come join us @sheffielduni for a PhD on the evolution and development of feathers and flight! 🐣🔬
This project is supervised by @Mattowers1 @AlexGFletcher, and I'm excited to be involved as a project advisor. Please share!
findaphd.com/phds/project/bb…
1
19
58
3,206
Alex Fletcher retweeted
31 Oct 2025
🚨 PhD Projects 🚨
We are advertising two UKRI funded PhD projects at
@sheffielduni through the @The_MRC with @AlexGFletcher and the @EPSRC with @emmafromthelab . #stemcells #development #embryology #reproductivephysiology #mathmaticalmodelling #quantitativebiology
2
7
207
Alex Fletcher retweeted
26 Jun 2025
Embryonic chimeras: donors in, hosts out
Read this Research Highlight showcasing work from @StanStrawbridge, @AlexGFletcher, Jennifer Nichols and colleagues (@SCICambridge @PDN_Cambridge @Cambridge_Uni @shefmathbio @sheffielduni @mrc_hgu @EdinburghUni):
journals.biologists.com/dev/…
ALT Figure 2 (B) Representative maximum intensity projections of confocal z-stacks for chimeras injected with ten Fgf4−/− ESCs showing high (Hi; n=24) or low (Lo; n=17) donor contribution, non-injected embryos (n=25) and ten Fgf4 / ESC-injected chimeras (n=34).
2
7
23
1,473
Alex Fletcher retweeted
5 Mar 2025
Come join us at @sheffielduni for an really cool PhD project with @Mattowers1 and @AlexGFletcher 🐤🦈🔬!
3
8
678
Alex Fletcher retweeted
20 Jan 2025
Excited to announce the first UK Maths Bio Conference 4-5 September in Birmingham ukmathbioconference.github.i… Registration opens soon! Thanks to my amazing co-organisers @Valeria_Giunta_,
@FabianSpill, Rachel and
@pearce_maths and the advisory board. Please help spread the word!
3
6
893
Alex Fletcher retweeted
10 Dec 2024
Last chance to register for the 8-10th January cell based Chaste modelling workshop @UoNCMMB - applications close Friday: chaste.github.io/workshops/2…
1
1
204
Alex Fletcher retweeted
25 Nov 2024
🚨A PhD project to develop an in vitro human implantation platform is available with an interdisciplinary supervisory team of @emmafromthelab, @IvanaBarbaric3, @3dBiomat, and myself.
#embryo #endometrium #biomaterials #blastoids #endometrialAssembloids
tinyurl.com/ycykmwv4
1
7
16
2,032
Alex Fletcher retweeted
9 Nov 2024
Happy to share our latest preprint, where we combine #chimera assays and #mathematicalModeling to reveal how spatial crowding and #Fgf4 signalling influence cell-fate decisions in the early #mouse #embryo. #stemcells #development
doi.org/10.1101/2024.11.08.6…
1/3
1
4
21
1,706
Alex Fletcher retweeted
24 Oct 2024
🚨 Job alert in theory/devbio/mathbio 🚨Official applications for PhD/postdoc opportunities in the Hiscock lab are now live! Check out twhiscock.github.io/ for links. Deadline 10 November.
22
29
7,081
Alex Fletcher retweeted
8 Jul 2024
🚀 We're recruiting Theme Leads & Fellows for our Centre for Machine Intelligence (CMI)! The CMI is a strategic AI investment, fostering regional development and policy discussion globally.
Find out more: sheffield.ac.uk/machine-inte…
youtube.com/watch?v=K-wP0wN1…
#AI #UoS #AIJobs #CMI #ML
1
14
14
3,214
Alex Fletcher retweeted
23 Jul 2024
Our department @sotonbiosci is hiring SEVEN faculty positions (Lecturer, Associate Professor, Full Professor) across many areas of biological sciences.
Come join a vibrant and inclusive environment.
Check out the link for more details 👇
Please RT
talentedu.com/uos/biosci/
28
30
7,132
Alex Fletcher retweeted
16 Jul 2024
JOB 🚨: Postdoc position in the School of Maths at the University of Nottingham, working on machine learning methodology for rapid model calibration of cardiac digital twins.
jobs.ac.uk/job/DIQ932/resear…
Closing date: 8th August 2024
Please RT!
2
16
24
3,752
Alex Fletcher retweeted
9 Jul 2024
We're hiring! 2 exciting #postdoc positions available @BristolUni to investigate mechanisms regulating epithelial cell fate during tissue morphogenesis and cancer. Generously funded by @wellcometrust. Great scientific environment and facilities in a vibrant city.
Please share 🙏
1
87
133
20,772
Alex Fletcher retweeted
10 Jul 2024
Fantastic 3 year postdoc in lovely Durham working on developing methods in fluid dynamics with an excellent colleague. Great opportunity to do some meaningful and deep fluid dynamics/scientific computing work!
durham.taleo.net/careersecti…
18
29
4,381
Alex Fletcher retweeted
9 Jul 2024
If you're thinking about applying Fellowships, our Fellows community is amazing, and we offer a huge amount of support to our incoming Fellows- you can find out more about our #Fellowship support here: sheffield.ac.uk/science/rese…
10
9
2,760
Alex Fletcher retweeted
16 Feb 2023
Our new department of Systems Biology at the MD Anderson cancer center in Houston Texas has open faculty positions for assistant professors interested in technology development, cancer evolution and systems biology @MDAndersonNews Apply here: mdanderson.org/about-md-ande……
5
48
119
23,722
Alex Fletcher retweeted
3 Jun 2024
📢Our paper on self-organized information in development is now out in @PNASNews!
See below for a 🧵 on the preprint and check it out here👉pnas.org/doi/10.1073/pnas.23…
17 Dec 2023
📢New preprint!
Developmental systems have a remarkable ability to self-organize spatial patterns of different cell types.
How can we quantify the information content & robustness of these self-organized patterns across biological systems?
👉arxiv.org/abs/2312.05895
9
17
140
16,376
Alex Fletcher retweeted
24 May 2024
There are similarities with comparable vertebrate embryonic epithelia, in which AP-patterning is also known to orient cell divisions, but our results suggest that more work is needed to understand the influence of mechanics on division orientation in vertebrate epithelia 5/5
1
1
125