Ph.D in Neuroimmunology π«π· | Post-Doctoral fellow π¨π¦
Joined September 2022
- Tweets 235
- Following 151
- Followers 106
- Likes 2,412
23 Photos and videos
Pinned Tweet
Feb 25
WE. DID. IT. π @SophieUgolini !
Thrilled to share our published study uncovering how sensory neurons shape disease tolerance to HSV-1 infection in the skin and DRGsβ¨!
Huge thanks to our team & collaborators who made this possible (in π«π·, π¨π¦ and πΊπΈ)!
cell.com/immunity/fulltext/Sβ¦
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Apr 14
Their journey was much shorter and ended much better than the journey a typical paper goes through before getting published
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Apr 13
π₯
Apr 13
OBS Neuroimmunology Webinar
"Neural control of Immune response in viral infection"
π©βπ¬ @AnaisRger @SophieUgolini @CIML_Immunology @queensu @ImmunityCP
π©βπ¬ Nicole Amanzar @IsaacChiuLab @IsaacMChiu @harvardmed
ποΈ Thursday 12mp ET
*Zoom: us02web.zoom.us/meeting/regiβ¦
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Apr 4
πππ
37 degrees Celsius. That is the temperature where your scRNA-seq experiment starts lying to you.
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37 degrees Celsius. That is the temperature where your scRNA-seq experiment starts lying to you.
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Mar 21
Excited to share our latest review: βThe Dorsal Root Ganglia: From a Neuronal Relay to a Sensory Organ.β just published in @AnnualReviews of Neuroscience π§ !
@UdeMTalbotlab, @o_harald π
annualreviews.org/content/joβ¦
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Mar 10
ππ»ππ»ππ»
Mar 10
Persistent interferon signaling causes sensory neuron plasticity and pain before and during arthritis @NatureNeuro
nature.com/articles/s41593-0β¦
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Feb 26
Congrats to the Ugolini Lab on this great neuroimmune paper in the skin!
Feb 25
#EveryCellIsAnImmuneCell! Ugolini, Roger &co show @ImmunityCP that herpes simplex virus #HSV1 activates sensory neurons that produce neuropeptide SP to limit neutrophil influx & TAFA4 that drives IL-10 by macrophages, overall fostering disease tolerance! doi.org/10.1016/j.immuni.202β¦
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Mar 10
Pleased to share our latest work by Lily He, Parth Bhatia, Shams Bhuiyan et al. combining human and mouse DRG multi-omics with in vivo AAV screening to identify enhancers that bias gene expression toward distinct classes of nociceptors. @NIH_NINDS & HEAL
biorxiv.org/content/10.64898β¦
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Mar 5
Warm congratulations to The Brain Prize winners 2026, Professor David Ginty and Professor Patrik Ernfors, for their pioneering work on how the nervous system detects and processes touch and pain.
@hhmi_science
#Neuroscience #BrainPrize2026
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Feb 25
#EveryCellIsAnImmuneCell! Ugolini, Roger &co show @ImmunityCP that herpes simplex virus #HSV1 activates sensory neurons that produce neuropeptide SP to limit neutrophil influx & TAFA4 that drives IL-10 by macrophages, overall fostering disease tolerance! doi.org/10.1016/j.immuni.202β¦
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Feb 27
HSV-1-activated sensory neurons produce substance P and TAFA4, which act in a tissue-specific manner to modulate inflammation and promote disease tolerance without affecting viral clearance @ImmunityCP
cell.com/immunity/fulltext/Sβ¦ @SophieUgolini @AnaisRger π«π·
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Feb 20
"Why do females experience longer-lasting pain?"
After five years of Ph.D. work, it is finally out in @SciImmunology !
Huge thanks to @GeoffroyLaumet for the mentorship and guidance!
science.org/doi/10.1126/sciiβ¦
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Jan 28
Prestige feels good, if you earned it. Fake prestige induces insecurity, selfishness, and depression. Even if deserved, you still can't eat a prestige sandwich. Focus on science, working with authentic people, and having fun.
linkedin.com/posts/jamesgilcβ¦
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11 Dec 2025
"In many gene expression studies, cells are extracted by tissue dissociation and fluorescence-activated cell sorting (FACS), but the effect of these protocols on cellular transcriptomes is not well characterized and is often ignored."
nature.com/articles/nmeth.44β¦
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8 Dec 2025
When your entire PhD depends on dry ice, FedEx, and clearing customs
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5 Dec 2025
Another uncomfortable fact: dissociating cells dramatically changes their patterns of gene expression, with immediate early genes turning on in minutes and a whole host more within ~half an hour of an exogenous stimulus (and chewing up tissue is a big one.)
4 Dec 2025
Simple result in Nature shows flow doesn't just destroy spatial context but tosses out important biology. Activated T cells are usually physically stuck to tumor cells and gating pipelines toss them out. Up to 91% of T-cell/tumor clusters gone. A huge fraction of clinical IO papers that used single-cell flow on dissociated tumors have systematically deleted the most tumor-reactive cells and then drawn conclusions from what was left
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15 Oct 2025
When Macrophages Disappear, Skin Blood Vessels Age!
Check out our new study @Nature that uncovers how the loss of specific macrophages with age blocks vessel repair and blood flow, revealing a new cellular trigger of tissue aging. #Aging #Immunology
ππ
nature.com/articles/s41586-0β¦
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13 Oct 2025
Congrats @KevinJTraceyMD and the @SetPointMed team! Neuroimmunology is not a concept - itβs real biology, technology, and medicine in real time!
13 Oct 2025
Weβre honored that the SetPoint System has been named one of @TIMEβs Best Inventions of 2025 in Medical & Healthcare. π
Read about it here: time.com/collections/best-inβ¦
Please see important safety information at spm.care/ISI
#TIMEBestInventions #StartActivating #RA
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13 Oct 2025
#DAMPsPower! Balachandran, Yin &co show @Nature that upon influenza #IAV or herpes #HSV1 virus infection, ZBP1 induces cell death by sensing #host-derived endogenous retroelement Z-RNAs produced in response to virulence factors! nature.com/articles/s41586-0β¦
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