Always great to listen to @KimmieNgMD She discussed the Coming Wave of Early-Onset Cancer. With it on the rise we need to do more for these patients. A dedicated program can help with coordination of supportive care service like fertility preservation! @ASCO#ASCO26@FightCRC
We need 500 climbers by July 1.
#Climbforacure is going nationwide, and you can join from anywhere.
Free to join. No travel required. Climb your way.
Register today: fightcrc.org/climb
Come talk to me about patient-reported outcomes! See results of PROs in the ATOMIC A021502 trial - Atezolizumab mFOLFOX6 vs mFOLFOX6 for adjuvant colon cancer. #ASCO26@ALLIANCE_org
#ASCO26 Abs LBA #3508: EPISODE-III (JCOG 1503C) randomizes ONLY stage III #coloncancer pts to ASA 100 mg x 3 yrs vs. placebo post adjuvant chemo. Primary endpoint = DFS. #cancer#cancerresearch@OncoAlert
Differs vs. ALASCAA trial (Martling et al; NEJM, 2025)
EPISODE-III
๐Stage III colon
๐PIK3CA MT was not required (PIK3CA MT analysis is ongoing)
๐Adjuvant therapy was required
๐ In unselected patients, ASA 100 mg was not beneficial for DFS
Thank you so much to the @ColonCancerCoal for their steadfast commitment to collaboration and fighting this disease together ๐ appreciate you so much!!! @EKPPRMPLS and Chris Evans ๐ #strongertogether@fightcrc
#ASCO26: LBA #3501- Optimal duration of #adjuvant#chemotherapy (ACT) in resected stage I-IV #colorectal#cancer: Galaxy Japan #ctDNA dynamics.
๐No benefit from continuing ACT if neg
๐ Also suggests no benefit to continue > 3M if neg
๐Rise in ctDNA at 3M suggests do NOT continue
๐For my practice, the role of #ctDNA dynamics will be CONSIDERED as an additional tool during ACT. @asco@OncoAlert
#ABS #3502 #ASCO26: Observation vs. Maintenance #PD-1 therapy after clinical complete response (cCR) in dMMR/MSI-H managed with #NOM suggesting holding IO therapy at time of cCR does not negatively impact prognosis. @ASCO#cancerresearch@OncoAlert#cancer
@ASCO#ASCO26 LBA 3500: DFS and TTR with ctDNA for adjuvant treatment in Stage II colon CA presented by Dr. Folprecht limited by:
๐Low ctDNA only 2.9%
๐ Created 10 yrs ago with limited 81 gene assay
๐ Closed early due to loss of funding
๐Remains prognostic for DFS and OS
@ASCO#cancerresearch#cancer@OncoAlert