We are the Balko Research Lab at VUMC, a translational cancer research lab at the interface of tumor biology and immunotherapy. Opinions RR own.

Joined February 2019
65 Photos and videos
New from our lab in @ScienceTM: Peripheral blood transcriptional profiling predicts breast cancer tumor subtype and response to neoadjuvant chemoimmunotherapy.
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This was a collaborative effort across multiple institutions! A huge shout out to my twitterless co-first author Alan Gutierrez and my PI @CardioOncology, along with all co-authors and funding sources. @Pan_Ma_ @ScientistBaylis @LavineLab @BalkoLab @SarnoffCardio @czbiohub
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New #JITC article: Monitoring systemic immune responses to checkpoint inhibition in breast cancer reveals host responses and mechanisms of resistance jitc.bmj.com/content/13/12/e… @BCT255 @BalkoLab
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New study 👉Dynamic single-cell systemic immune responses in immunotherapy-treated early-stage HR #BreastCancer patients. 🔓 pubmed.ncbi.nlm.nih.gov/4061… @MargaretAxelrod @stolaney1 @EMittendorfMD @BalkoLab
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Looks amazing! Great work @ECBrunner!
Check out this article that made the 2025 cover of Cancer Research Communications: Epithelial Expressed B7-H4 Drives Differential Immunotherapy Response in Murine and Human Breast Cancer brnw.ch/21wQki5 @BalkoLab
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State of the Art: The Winding Road of Immune Biomarkers in Early Breast Cancer—Roberto Salgado, Justin Balko, and Priyanka Sharma will address this topic in this special session at #SABCS24 (December 10-13). Learn more: bit.ly/3BjXxfB @BalkoLab @psharmalab
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14 Oct 2024
State of the Art: The Winding Road of Immune Biomarkers in Early Breast Cancer— Roberto Salgado, Justin Balko, and Priyanka Sharma will address this topic in this special session at #SABCS24 (December 10-13). Learn more: bit.ly/4h3tAR0 @BalkoLab @psharmalab
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22 Sep 2024
Next, @MargaretAxelrod talks about patient and tumor specific biomarkers in ici myocarditis👌 #gcos #gcos24 @ICOSociety @BalkoLab @CardioOncology
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31 Jul 2024
As we better understand mechanisms that may drive ICI-myocarditis, we can think of more targeted therapies! Work by many individuals including @DrJESalem @JimAllisonPhD @CardioOncology @BalkoLab have led to ideas of targeting CD80/86, JAK-STAT signaling pathways, and T-cells! 6/
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Meet Immuno-oncology Senior Editor Justin M. Balko, PharmD, PhD. The @BalkoLab is focused on improving treatment outcomes in BC & other solid tumors, as well as the intersection between immunotherapy and tumor biology. Read the latest articles: bit.ly/3Lajnn3
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#ASCO24 Poster Session | Analysis of the sensitivity to endocrine therapy assay in the PALLAS adjuvant trial of palbociclib in HR /HER2- #breastcancer (ABCSG-42/AFT-05/BIG-14-13). @Otto_DFCI @elmayermd @MichaelGnant @AngieDemichele @ChristinaCurtis @cncurtis @BalkoLab
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Komen grantee @BalkoLab presents his work on understanding and improving #breastcancer response to immunotherapy @ #AACR24. To learn more, check out the MBC Impact Series where he discussed his work: bit.ly/4cFtpsN
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So proud of this outstanding scientist and person @BCT255 defending her thesis today. A @SusanGKomen ASPIRE scholar, @CD_AACR @jitcancer published author and all around superstar. Can't wait to see what the future holds!! @VUMCResearch @VUBasicSciences
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This line up!!! Phenomenal. @sitcancer Spring Scientific. Happening NOW!
Look at that lineup! So excited to co-organize (@JennGuerriero @JenWargoMD) the @sitcancer Spring Scientific #SprITC2024 focused on metabolism in cancer immunotherapy! Hope you can join us!
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I am defending my dissertation next week on March 15th! Grateful for the mentorship by @BalkoLab ! DM me if you would like the zoom link.
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Rock.Star. Great talk with wonderful implications for the next generation of myeloid therapy in ccRCC. Can’t wait to see what you do next!

Congratulations to newly minted Dr. @melissa_m_wolf ! Co-mentored with @KimrynRathmell in @VUMC_Cancer, we're proud of what you've done and excited for the next steps!
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From the latest issue— #NKG2A is a Therapeutic Vulnerability in #Immunotherapy Resistant MHC-I Heterogeneous Triple Negative #BreastCancer, by @BCT255, @SXPung, @BalkoLab et al. bit.ly/49WMp43 @VUMCDiscoveries #TNBC
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Super excited for next year's meeting! Only 290 days and counting (OK you got me... I didn't do the math I just guessed 😂)
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Excited to see the *official* version out!!! Great job by the editorial staff... It looks phenomenonal!
From the February issue— #NKG2A is a Therapeutic Vulnerability in #Immunotherapy Resistant MHC-I Heterogeneous Triple Negative #BreastCancer, by @BCT255, @SXPung, @BalkoLab et al. bit.ly/49CFb4U @VUMCDiscoveries #TNBC
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