Joined November 2015
- Tweets 154
- Following 67
- Followers 330
- Likes 72
14 Photos and videos
The Harris Lab retweeted
16 May 2025
So excited to share our latest work with Sarat Chandarlapaty, @antoniomarraMD, Andrea Gazzo @MSKCancerCenter out today in @NatureGenet! We uncover the function and mechanism of APOBEC3-driven therapy resistance in breast cancer. 🧵 1/
nature.com/articles/s41588-0…
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7 Mar 2025
Great representation at the 1st Annual Biochemistry Research Day at UTSA.
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10 Feb 2025
Carcinogens in tobacco smoke leave the genome vulnerable to deamination by viral restriction factor APOBEC3B.
This new pattern of mutations known as “Didyma” can help delineate the origins a different cancers.
Check out the full Pre-Print here:
biorxiv.org/content/10.1101/…
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The Harris Lab retweeted
29 Apr 2024
🚨 APOBEC3B (A3B) is a major source of🧬mutation in cancer
The active site is like Teflon (not much binds) BUT @Ozlem__Dmr discovered a druggable allosteric site đź‘€
Experiments by @DanHarki @_ChemKat @HarrisLabUTHSA đź’Ş
biorxiv.org/content/10.1101/…
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What a great way to start the day. This superb work from the Pillai lab, driven by Prajwal Boddu and a little help from us @bdelapenavalos is finally in print @MolecularCell Highlight: SF3B1 oncogenic mutations reduce RNAPII gene-body elongation rate. sciencedirect.com/science/ar…
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The Harris Lab retweeted
26 Feb 2024
We thank our program committee for creating a great #SABCS24 lineup.
@VKaklamani @CarlosArteagaMD @BalkoLab @tperrybrown @heide_ford @HarrisLabUTHSA @TariKingMD @lab_kok @Adrianvlee @itsnot_pink @hmcarthur @dapattmd @c_sotiriou @atanmdlci @NeilVasan @adawaksmd @awolff @AACR_CEO
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The Harris Lab retweeted
12 Dec 2023
đź“Ł Hot off the press! @NAR_Open
Delighted to share our latest work!
Thanks to all collaborators and contributors.
Fresh off the press! The protein phosphatase EYA4 promotes homologous recombination through dephosphorylation of Y315 on RAD51. Hardest research paper since my postdoc years! Thx team! @bdelapenavalos @RTropee @DuijfLab @JeanYvesMasson @leunglaboratory academic.oup.com/nar/advance…
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The Harris Lab retweeted
2 Oct 2023
Excited to share that our paper was officially published in Molecular Cancer!👇
Read more about EYA4 and its role in promoting breast cancer progression and metastasis here: rdcu.be/dnzkx
A big thanks to @dray_lab and fantastic collaborators @RTropee and @DuijfLab.
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15 Sep 2023
Congratulations to Arad and Sofia for defending their respective PhD theses! This marks the official sunset of the Minnesota Harris Lab. We wish them the very best in their next steps!
ALT Sofia's defense
ALT Arad's defense
ALT Arad and Sofia graduation ceremony
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The Harris Lab retweeted
12 Aug 2023
Happy to share our last findings on HCMV evasion of APOBEC3 restriction!🤩
Human cytomegalovirus mediates APOBEC3B relocalization early during infection through a ribonucleotide reductase-independent mechanism | Journal of Virology journals.asm.org/doi/10.1128…
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6 Jul 2023
Big news from Midwest AViDD Center featuring
@elisafanunza @GuptaYogeshTX and Shaun Olsen
5 Jul 2023
Midwest AViDD Center announces funding for six high-potential projects to further antiviral drug discovery midwestavidd.umn.edu/midwest… @umnmedschool
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26 Jun 2023
Don't miss the great work by members of our virus team this year at ASV! Elisa is sharing her poster at 8:30 PM at P22-23 and Ashley's work can be found at P10-8. #ASV2023 #LoveVirology
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30 May 2023
Check out the latest publication from PhD student Jordan Naumann! She utilizes the hydrodynamic FAH delivery system to show "DNA Deamination Is Required for Human APOBEC3A-Driven Hepatocellular Carcinoma In Vivo" mdpi.com/2312926 #mdpiijms via @IJMS_MDPI
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24 May 2023
Congratulations to Dr. Amanda Rieffer for a successful PhD thesis defense last Friday! We wish her the very best in all future endeavors!
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15 May 2023
Beautiful story by our very own @JordanBeckerPhD and student @Ashley_Auerbach Congratulations on the cool discovery!
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11 Apr 2023
Don't miss the latest work from our PhD student Arad, his gain-of-signal assay is prominently featured in @ScienceAdvances
science.org/doi/10.1126/scia…
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2 Mar 2023
Congrats to our student Cameron Durfee and his preprint on #bioRxiv He demonstrates human APOBEC3B can drive tumor formation in vivo. Check out this beautiful story below!
26 Feb 2023
Human APOBEC3B promotes tumor heterogeneity in vivo including signature mutations and metastases biorxiv.org/cgi/content/shor… #bioRxiv
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The Harris Lab retweeted
30 Dec 2022
The birth of the antiviral gene APOBEC3B in ancient primates is linked to the evolution of a potent counterdefense by herpesviruses, a host-pathogen interaction maintained to the present day. elifesciences.org/articles/8…
ALT A superposition of the three highest-ranked protein-protein docking models of the KSHV ORF61-A3Bctd complex in pink, yellow and blue, generated using RosettaDock
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The Harris Lab retweeted
5 Dec 2022
My 1st first-author manuscript is out in @eLife! This project started back in 2019 with the question “what makes a viral protein evolve a new function?” A thread:
doi.org/10.7554/eLife.83893
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The Harris Lab retweeted
14 Nov 2022
Excited that my first co-first author paper was officially published today on mSphere!
Read more about APOBEC3B nuclear localization here: journals.asm.org/doi/10.1128…
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