Chen Jinmiao Lab for single cell Immunology and AI

Joined April 2023
9 Photos and videos
Excited to share our latest work in @NatureGenetics (nature.com/articles/s41588-0…). We introduce SpaMosaic, a new computational method designed to advance spatial omics by mosaic integration of diverse datasets with partially overlapping modalities.

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It provides a versatile framework for unifying the rapidly accumulating heterogeneous spatial omics data into comprehensive tissue atlases.
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Huge thanks to the incredible team and collaborators who made this possible!
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Happy to announce that our Nature Methods paper 'SpatialGlue' was recently featured in A*STAR Research: research.a-star.edu.sg/artic…

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We would like to announce that disco has moved to disco.bii.a-star.edu.sg/. Thank you for your support ☺️

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Congratulations to Azimuth 2. Delighted that Disco is contributing to this initiative 😊
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Jinmiao Chen Lab retweeted
Excited to share our latest @NatureMedicine study from our new center @ARC_Neuro! 🧠✨ Using spatial transcriptomics & scRNA-seq, we uncover how Aβ-targeting immunotherapies shape microglial responses in AD patient brains. A thread with our key findings is below! 🧵(1/15)
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Congratulations and very nice study @DGateLab 🙂
7 Mar 2025
More excellent work from the brilliant @LynnOlst. I’m a very proud PI today. More to come from @ARC_Neuro!
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Lab Gathering Lunch and Chinese New Year celebration 🎉🎉🥳 Also all the best to @LongYahui and chengwei as they embark on their new journeys 😊
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Jinmiao Chen Lab retweeted
🎉 Congrats to the Singapore research team on ezSingleCell! 🎉 A game-changer for #singlecell & #spatialbiology, it simplifies data analysis from platforms like Chromium, Visium & Xenium without programming expertise! 🚀 Learn more: nature.com/articles/s41467-0…
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Jinmiao Chen Lab retweeted
9 Dec 2024
🚀 DISCO December Update 🚀 📊 8,529,538 cells from 1,345 samples across 94 projects added in this month's update! 🎉 Dive in and explore the data that matters to you! 🧬 Check it out here: immunesinglecell.org/ #Bioinformatics #SingleCell #LLM #DISCO
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Jinmiao Chen Lab retweeted
8 Dec 2024
🎉 Excited to share that our paper DISCO: a database of Deeply Integrated human Single-Cell Omics data has reached 100 citations! 🚀 Grateful for all the researchers utilizing and building upon DISCO. Here's to advancing single-cell biology together! 💡📊 #SingleCell #Bioinformatics scholar.google.com/citations…
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Jinmiao Chen Lab retweeted
Our keynote of Career Day is a FEBS-powered breakout lecture by Dr. Jinmiao Chen (@CJM_lab)! 🌟 She introduces the fundamentals of spatial omics and shares her lab's cutting-edge AI-driven analysis method, STAMP (Zhong et al., 2024). 🚀
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Jinmiao Chen Lab retweeted
22 Nov 2024
🚀 scEnrichment Update! The scEnrichment tool now features an updated reference geneset with 524 cell type 🧬 and phenotype 🔬-related genesets! 🎯 Input your geneset to uncover enriched phenotypes or cell types with ease. 🔗 Try it here immunesinglecell.org/tool/sc… #scRNAseq #Bioinformatics #Genomics 🧑‍🔬✨
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Jinmiao Chen Lab retweeted
15 Nov 2024
Rediscovering publicly available single-cell data with the DISCO platform academic.oup.com/nar/article…

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Jinmiao Chen Lab retweeted
13 Nov 2024
🚀 Exciting update! DISCO now supports batch downloads—access data from 113,277,088 cells across 18,402 samples with ease. Perfect for training your LLMs or fueling other applications! 🌐📊 #SingleCellData #Bioinformatics #AI @LLM immunesinglecell.org/downloa…
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Jinmiao Chen Lab retweeted
Our data showed varied functions of myeloid cells in early life while identifying therapeutic targets. We are grateful to our collaborators @FGinhoux @HongyanWang9 @lai9uan @CJM_lab @Abhay_R_ and their teams for all their support, ideas, tools, and enthusiasm over the years!
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