LETS make something clear.... 👉This is not, never was, never will be a PROFESSIONAL account 👉 You want a professional encounter make a formal appointment 👉 If you insult me I WILL no longer remain quiet 👉 You don't like it I suggest you unfollow this account.

An 80-year-old woman with advanced Alzheimer's, all but silent for five years, took 5 grams of psilocybin and woke up the next day telling stories about her life. This case study was published just a few days ago in Frontiers in Neuroscience, and I can't stop thinking about it. She had lived with Alzheimer's for a decade. The last five of those years she spent in the state we are all taught to dread: she was incontinent, could barely walk, and couldn't dress herself. Her speech had collapsed into single syllables, and her family had come to a painful acceptance that the woman they remembered was no longer reachable. Then she took five grams of psilocybin mushrooms in a single supervised session in Brazil. The first hours of her journey were hard, with heavy sweating and a long, deep sleep-like state. Then, roughly nineteen hours later, she woke and spoke about her own life for close to four hours, pulling up real memories and events from her past. Over the following days, the changes kept coming. She regained bladder control after five years. She started dressing herself and walked with far less help than before. She started meeting people's eyes again. She recognized her family and remembered who had visited her and what they had said. A month later, with the improvements still holding, the clinicians gave her a second, smaller dose of 3 grams. In that session, she described surfing with her son on a peaceful island, her whole face lighting up as she spoke. At one point, she looked at the people caring for her and said, simply, "It is pleasant to come here." Her neurodegeneration is still there, and many of these improvements lasted for only weeks. Psilocybin did not completely reverse her Alzheimer's. But it forces a new potential to the surface, one that would stop any family that has lived through this in its tracks. We have treated the silence of late-stage dementia as a direct readout of dead tissue. We assumed the lost functions were gone, erased along with the neurons. This case suggests those functions may never have been destroyed at all, only locked away, and that a powerful enough shake-up of the brain's networks can briefly make them accessible again. I wrote recently about a 92-year-old woman with advanced Alzheimer's who had slipped into a near-vegetative state after eleven years with the disease. Once her caregiver began giving her microdoses of LSD, she started talking, reading, and recognizing the people she loved, and her wit and personality came back with her. Both psychedelics produced the same result no one thought was possible: a person their family had already grieved, back in the room with them for a while. If this much can come back, even briefly, then the question worth asking is what else we could reach through responsible psychedelic therapy. Which neurological condition would you most want to see psilocybin studied for next?

Preserving lean mass during tirzepatide (Zepbound) treatment. A randomized trial of a myostatin inhibitor for muscle mass building shows proof-of-concept. A 55% retention of lean mass compared with placebo nature.com/articles/s41591-0… just published @NatureMedicine

No es normal, cualquier PENDEJO estudia medicina. SER alguien exitoso ya es otra cosa. Y aún así lo superior es cuestionable….

Well that is FUGLY 🤣

Researchers show that a type of #AI known as a large language model often outperformed physicians at diagnosing complex and potentially life-threatening conditions, including decreased blood flow to the heart, even in the fast-moving stages of real ER care when information is limited. In early ER cases, the model identified the correct or a very close diagnosis in about 67% of cases, compared with roughly 50% to 55% for physicians. And the technology is only getting better. Learn more: scim.ag/4w909UX

Robert Sapolsky es un neurocientífico de Stanford que demostró que el estrés crónico es el asesino silencioso que los médicos ignoran. Reveló 10 hábitos que haces todos los días y que te quitan años de vida. 1) Repasar conversaciones en tu cabeza

🚩😴 DORMIR POCO IMPIDE QUE PIERDAS GRASA Y GANES MÚSCULO ⚠️En comparación con dormir 7 horas por noche, dormir 5,5 horas por noche causa: ❌MISMA pérdida de peso, PERO: ⇩⇩ 50% MENOS pérdida de grasa. ⇧⇧ 50% MÁS pérdida de masa muscular.

Here is another example on how to STUDY while exercising. I’m liking this a lot @SCAI CME

Doing some CME of the @SCAI curriculum with the Metaquest while exercising. Pretty #Awesome

Shit… You want to feel old? It has been 20 years since the Star Wars KID video appeared youtu.be/HPPj6viIBmU?si=93Y5…

No digan mamadas 🤣 Dar un mejoralito y una sobada no es salvar. Bola de Puñales

Aquí viendo un paciente en McAllen y dice que se pasaron a México hace 15 días y los balacearon. Le pegaron a su hijo en Reynosa Y luego el gobierno diciendo que las cosas están bien. 🖕🖕🖕🖕🖕

Best evidence yet that GLP-1 drugs reduce the risk of substance abuse, from >600,00 US Veterans across alcohol, nicotine, opioid, cocaine, cannabis @bmj_latest @zalaly @Miao_Cai_SLU bmj.com/content/392/bmj-2025…

Seriously do the world a favor and just STFU

Na mamar

Saben quien fue el primer THERIANO???? Cuauhtemoc Blanco…

Every few months, I write an updated, idiosyncratic guide on which AIs to use right now. My new version has the most changes ever, since AI is no longer just about chatbots. To use AI you need to understand how to think about models, apps, and harnesses. open.substack.com/pub/oneuse…

The government wants AI doctors. In 60 days, four new initiatives have launched: - ARPA-H ADVOCATE: funding an autonomous AI cardiologist. - CMS ACCESS: pays for outcomes, not visits, with reimbursement set that you have to use software to scale. - FDA TEMPO: lets AI devices deploy before full clearance - Utah: AI can prescribe medication (refills at first). AI is coming to care delivery.

Nuevo Estudio de Pádel

Some lyrics of BadBunny… Translate Te escupo la boca, te jalo el pelo Te doy con el bicho y con el lelo En el jet privado, un polvo en el cielo Hoy quiero una puta, una modelo, ey (Ay, ay) Ah, mami, chapéame, no me molesta, je Que despué' yo te voy a romper con el néctar