The Halfmann Lab explores the cellular and evolutionary implications of protein self-assembly.
Joined September 2015
- Tweets 212
- Following 96
- Followers 593
- Likes 107
14 Photos and videos
Mar 27
"Set Phasers to Kill." Derek Lowe's take on our @eLife paper on phase change batteries and cell death is as accurate as it is engaging. Impressed and grateful for the coverage @ScienceMagazine! science.org/content/blog-pos…
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16 Oct 2025
Also, check us out on NPR.org front page! Congrats again @arg_arginine. Thanks to pioneering structural biology of death domains (DFDs) from @WuLabHarvard and previous collab with Zhijian 'James' Chen @UTSWMedCenter that led us to the protein batteries concept.
10 Oct 2025
Why would a healthy cell decide to die? Investigator @HalfmannLab joined @NPR's @npratc with @NPRjonhamilton to discuss his #research on how and why cells decide to self-destruct—a process known as programmed cell death.
🎧 Listen here: n.pr/3L4i1gF
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Halfmann Lab retweeted
29 Jul 2025
Alex Von Schulze, postdoc in the @HalfmannLab, is exploring how proteins clump together to form disease-linked amyloids, and why collaboration is the key to scientific discovery. 🧠 #neuroscience
Learn more in this #PostdocProfile Q&A: bit.ly/4momNmV
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3 Apr 2025
MD simulations let you watch a microsecond or so of one protein's life in a box. But in the cell thousands of proteins work together, over much longer timescales. With @IlyaVakser's group and their new simulation method, GCell, we're now beginning to see this emergent behavior!
31 Mar 2025
Delighted to share #MyACSCover and our recent study, "Highly Optimized Simulation of Atomic Resolution Cell-Like Protein Environment", published by @ACSPublications in J of Phys Chem B.
Congratulations to Prof. @IlyaVakser , @HalfmannLab , and the team!
doi.org/10.1021/acs.jpcb.4c0…
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Halfmann Lab retweeted
30 Apr 2024
1/n Can LLMs perform scientific research? And, can they do so while enhancing key scientific values including transparency, traceability & verifiability? Check out our preprint on the "data-to-paper" platform. w the amazing @TalIfargan @LostInTranscrip arxiv.org/abs/2404.17605
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Halfmann Lab retweeted
10 Apr 2024
Meet a #StowersGrad faculty member! Randal Halfmann (@HalfmannLab) seeks to understand #aging, the inexorable decline in cellular and bodily function that results from the unidirectional nature of self-assembly by supersaturated proteins. #PhD
Learn more: bit.ly/43TtyVw
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9 Oct 2023
Thank you, @eLife, for transparent review!
Exercising the power to publicly address a reviewer’s untenable position changed the outcome for our latest paper, the findings of which are recognized as “fundamental” by eLife’s updated assessment.
elifesciences.org/reviewed-p…
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9 Oct 2023
Kudos also to a responsive editorial staff, who offered to provide Senior Editorial oversight in the second round of review. I feel empowered to refocus on science rather than academic politics – this feels like the future of science publishing. @ASAPbio_
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Halfmann Lab retweeted
7 Sep 2023
one poster, 8 hands to hang it. #CRC2023 kicks off and everyone is excited to share their scientific discoveries with their peers. Great job @StowersXroads for organizing such a wonderful event @ScienceStowers. Shriram @HalfmannLab amazing presentation#researchtalks #scievents
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30 Jun 2023
Yes, science is FUN! (even for the nerds sitting in the corner with a calculator ;) Kate, thanks for helping make science accessible to everyone!
30 Jun 2023
#ICYMI: Today @HalfmannLab and @K8theChemist joined @adavalostv on @GreatDayKC to talk all things #STEMeducation and @seekingascipod, our #podcast with @kcur. 🎙️ @fox4kc
📺 Watch here: bit.ly/3r6OSaS
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19 Jun 2023
Ron is a pioneer on the mechanism of polyQ aggregation, and an inspiration to me. It was a nice surprise that our new in-cell method validated his twenty year-old model derived from rigorous test tube experiments. Good science stands the test of time!
14 Jun 2023
#ICYMI: New #research from the @HalfmannLab revealing the start of #Huntingtons disease published in @eLife. Here is what Ron Wetzel, PhD, @PittTweet @UPMC, had to say about the findings.
Read more: bit.ly/43XnOsB
#ScienceTwitter #Discovery
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14 Jun 2023
Proud moment in the life of an academic -- first @StowersGrad PhD student from my lab. @arg_arginine - you set a high bar!
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13 Jun 2023
Now out in eLife – our epic journey into the heart of polyQ to deduce the structure of an amyloid nucleus. Spoiler: it’s not #LLPS. Even more surprising, oligomerization blocks nucleation!
13 Jun 2023
“One of the big mysteries of #Huntingtons, #Alzheimer’s, and #ALS is why disease coincides with amyloid, yet the amyloids themselves are not the main culprits.” @HalfmannLab discusses new #research published in @eLife.
Read here: bit.ly/43QTDUF
#ScienceTwitter
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Halfmann Lab retweeted
16 Mar 2023
BIG NEWS! We've got an exciting new podcast coming your way 🥳
@K8theChemist, @kcur and the @ScienceStowers are teaming up for the new podcast Seeking A Scientist!
Sign up on the website to stay up to date! ✉️
#seekingascientist
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8 Mar 2023
Big congrats to @avonschulze for receiving an NIH F32 fellowship! Very well-deserved! Can't wait to see the outcome of his project testing fundamental mechanism of aging. @NIHAging @ScienceStowers
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Want to get in on unpublished findings that can change your research while taking in the gorgeous Irish coast? Then join us on June 11 for this important Science Research Conference! #PACSRC @thebaumlab @HalfmannLab @SaelicesL @UtsWcand
Register: bit.ly/3Ey974Y
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3 Mar 2023
Only 99 days until the The Protein Aggregation Conference: Exploring Rugged Landscapes #PACSRC. My fav conference, will be international for the first time in ~30 yrs. Come explore the seaside Irish landscape with us! web.cvent.com/event/720adec4…
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