Our lab works on understanding genome stability and its role in cancer, using model systems (yeast, worms, & cancer cells). Find us in Michael Smith Labs @ UBC.
Joined October 2015
- Tweets 177
- Following 82
- Followers 393
- Likes 78
12 Photos and videos
17 Jul 2025
Our latest work is now out in DNA Repair. Synthetic cytotoxicity profiling of cohesin mutants highlights recombi... sciencedirect.com/science/ar… @ubcmsl
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18 Jun 2025
Our collaboration with @StirlingLab now out at PNAS. Deep structure–function analysis of the endonuclease Mus81 with dominant mutational scanning | PNAS pnas.org/doi/10.1073/pnas.25…
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20 May 2025
Excited to see this interesting story get published. @ubcmsl Distribution of haploid chromosomes into separate nuclei in two pathogenic fungi | Science science.org/doi/10.1126/scie…
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19 Mar 2024
New SL paper from the Hieter and Stirling labs @stirlinglab . Mapping of DDX11 genetic interactions defines sister chromatid cohesion as the major dependency pubmed.ncbi.nlm.nih.gov/3847…
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Hieter Lab retweeted
12 Jan 2023
.@ubcpharmacy professor Dr. Corey Nislow & Dr. @philhieter of MSL's @HieterLab discuss yeast research from NASA’s #Artemis 1 lunar mission.
UBC scientist’s ‘mutant yeast’ from space could help future astronauts, cancer patients | Globalnews.ca globalnews.ca/news/9403445/s…
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Hieter Lab retweeted
9 Dec 2022
RAD18 opposes transcription-associated genome instability through FANCD2 recruitment dlvr.it/Sf4W0l
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Hieter Lab retweeted
27 Sep 2022
ALL-TIME RECORD | We are proud to award 90 new research grants valued at $10.8 million as part of our annual competition. The grants are awarded to some of the most promising cancer research projects in Canada. 🎉🔬
👉 bit.ly/3xUiHfe
#CancerResearchSociety
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Hieter Lab retweeted
16 Aug 2022
#GENETICS and #G3journal are pleased to announce a Call for Papers on Genetic Models of Rare Diseases. This new series is led by Brenda Andrews, Hugo Bellen, @dougfowler42, and @HieterLab; submissions for the launch issue are due November 14! #rarediseases bit.ly/3dtembD
ALT Computer-graphic of a colorful neuron advertising a Call for Papers on Genetic Models of Rare Diseases from GENETICS and G3 journals. Submissions due November 14, 2022.
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Hieter Lab retweeted
1 Sep 2022
🎉 Congratulations to everyone who received awards in August! ☀️
Dr. Philip Hieter (@HieterLab) received a @CIHR_IRSC grant to expand the impact and reach of the Canadian ‘#RareDiseases: Models and Mechanisms’ Network.
See more award winners:
scienceinvancouver.com/2022/…
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18 Aug 2022
The Hieter Lab is at #yeast22. Anthony Oppedisano is presenting "Mutational Scanning to find Synthetic Lethal interactions with the repair endonuclease Mus81" on Friday evening. Poster 177B.
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Hieter Lab retweeted
16 Aug 2022
I’m very excited to share that my PhD work is now published @eLife! We used a combination of genetics, cell biology and biochemistry to identify a new endosomal complex in yeast, which we named VINE 🌿 Early access here: elifesciences.org/articles/7…. (1/n).
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Hieter Lab retweeted
25 May 2022
Congratulations to Dr. Leanne Amitzi on her graduation today! 🎓 Dr. Amitzi, of the @HieterLab, has successfully earned her Doctor of Philosophy (#PhD) in Medical #Genetics ! 🎉🧬
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Hieter Lab retweeted
13 Apr 2022
Join us today for our seminar with Dr. Maitreya Dunham (@DunhamLab) from @uwgenome on "High throughput human genetics in yeast".
April 13th, 3-4pm, PST
Host: Dr. Phil Hieter (@HieterLab)
Event details & zoom registration:
msl.ubc.ca/event/msl-seminar…
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Hieter Lab retweeted
2 Dec 2021
Drs. Peter Stirling (@pcstirling), David Huntsman, & Philip Hieter (@HieterLab) received an @OvarianCanada/@SRC_CRS grant to develop drugs that will convert proteins that normally repair DNA into toxic agents that selectively kill #OvarianCancer cells. 🧬
bit.ly/3rrb6Cw
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31 Aug 2021
New from us in collaboration with the Moffat Lab at
@DonnellyCentre. Great work by Melanie Bailey using CRISPR screens to find STAG2 dependencies in 3 different cell lines.
31 Aug 2021
@HieterLab uses CRISPR-Cas9 screening to explore the context-dependency of genetic interactions of the cancer-mutated cohesin gene STAG2 in three different cellular backgrounds @HieterLab @ubcmsl
life-science-alliance.org/co…
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Hieter Lab retweeted
24 Aug 2021
Great review of disease modelling and drug discovery in worms! Really highlights how versatile worms are.
journals.biologists.com/dmm/…
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19 Aug 2021
We got the band back together for this Gpn2 RNA polymerase biogenesis story. Collaboration with @StirlingLab
tandfonline.com/doi/abs/10.1…
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Hieter Lab retweeted
29 Apr 2021
#CMHFLaureate @mmarra0630 head of the Personalized Oncogenomics project @BCCancer, using information derived from thousands of individual #cancer genomes & transcriptomes to identify promising therapeutic targets in individual patients bit.ly/3gNglXZ
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14 Apr 2021
Setting molecular traps in yeast for identification of anticancer drug targets pnas.org/content/118/18/e210…
An insightful commentary by @drgrantwbrown and Brenda Andrews of the @DonnellyCentre referencing our recent PNAS manuscript.
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30 Mar 2021
New from the Hieter lab at @ubcmsl : Modeling DNA trapping of anticancer therapeutic targets using missense mutations identifies dominant synthetic lethal interactions pnas.org/content/118/14/e210…
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30 Mar 2021
Great work by Akil Hamza and Leanne Amitzi who co-lead the project and characterized Fen1 and Chl1 respectively. Thanks to @CCSResearch and @CIHR_IRSC for the funding that made the research possible.
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