Grad student in the @HiebertLab @VUmedicine👩🏻🔬 Transcriptional control of cancer 🧬🤘🏼#firstgencollege
Joined September 2011
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12 Apr 2024
So excited to share the first half of my dissertation research. If you’re interested in transcription, enhancer activation, DLBCL, or B-cell biology, this one’s for you. Check it out in @CellGenomics!
11 Apr 2024
Our latest work is out now in @CellGenomics. @HillaryLayden and team use the dTAG system and deep genomic analysis to determine how wild-type and mutant FOXO1 control transcription in DLBCL. cell.com/cell-genomics/fullt…
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1 Feb 2024
I'm excited to announce that I'm defending on February 14th at 1 pm. See what I've uncovered about how mutations in FOXO1 contribute to B-cell lymphomas! Zoom link available; message me.
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Hillary Layden retweeted
3 Feb 2023
Has anyone updated their PRO-seq/GRO-seq adapters/sequencing primers to include dual indices for better results on the NovaSeq? Our current protocol is based on the TRUseq Small RNA kit but our core would like us to include a second index for better multiplexing. #Genomics
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Hillary Layden retweeted
17 Jan 2023
Check out our latest story in @MolecularCell. Our team pairs the dTAG system with deep genomic analysis to determine the spatiotemporal role of SMARCA5 in the maintenance of chromatin structure and function.
bit.ly/3GNCalx
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Hillary Layden retweeted
16 Nov 2022
Excited to share our newest story! Our team details how the fusion transcription factor PAX3-FOXO1 regulates RNAPII pause release at a small number of genes via the recruitment of co-regulatory complexes to specific enhancer elements in aRMS cells. shorturl.at/ceFHL
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Hillary Layden retweeted
12 Apr 2022
#AACR2022 PhD candidate Susu Zhang will be presenting her work on identifying the direct targets of PAX3-FOXO1 from 9-12 in poster section 7.
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Hillary Layden retweeted
26 Feb 2022
🇺🇦 Two of the most intelligent, talented, kind, and amazing mentors I have at @VUMC_Vaccines are from #Ukraine. I will share some ways that they have shared with our lab for anyone interested to #SupportUkraine in this short 🧵 1/
#DonateUkraine #UkraineUnderAttack #UkraineWar
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Hillary Layden retweeted
21 Feb 2022
I have not struggled with a story like I struggled with this one.
A thread for anyone interested in the reporting meta:
tennesseelookout.com/2022/02…
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Hillary Layden retweeted
5 Oct 2021
Hot off the (pre-print) presses! Our PAX3-FOXO1 team shows that the fusion transcription factor is required to coordinate enhancer activity at specific targets in aRMS cells and delves into the mechanisms underlying this coordination.
biorxiv.org/content/10.1101/…
5 Oct 2021
Check out our latest preprint on the deep mechanistic analysis including proteomics and 13 parameter genomics to define how PAX3-FOXO1 modulates transcription at those gene targets. @ScottHiebert1 @HiebertLab @VUMC_Cancer @VandyBiochem biorxiv.org/content/10.1101/…
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2 Oct 2021
Just found out I qualify as an underrepresented population because I received Pell grants for undergrad and my parents don’t have bachelors degrees. It’s weirdly comforting to know that the NIH recognizes this.
1 Oct 2021
I looked up what the NIH defines as an underrepresented population for purposes of diversity and inclusion and I was shocked to find out that I qualified.
The reason? I grew up in rural America.
My journey and why I think this is an important area for DEI efforts 👇
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Hillary Layden retweeted
15 Sep 2021
The Department of Biochemistry at Vanderbilt University is hiring new faculty! Apply here: apply.interfolio.com/94568
More info about @VandyBiochem here: medschool.vanderbilt.edu/bio…
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Hillary Layden retweeted
6 Sep 2021
*grad students talking about how they knew science/a PhD program was for them when they played in their parents research labs*
me, a first gen: this side quest seems fun 🤠
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Hillary Layden retweeted
23 Aug 2021
The Dept of Cell and Developmental Biology at Vanderbilt is beginning a search for new junior faculty this fall. This is an open search - looking for exceptional scientists in any area of cell/dev biology.
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Scientist Really Thought Job Would Be Less Grant Writing And More Glow-In-The-Dark Lizard Making bit.ly/3yOW3Ue
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Hillary Layden retweeted
20 Jul 2021
Gotta confess. Didn’t have Tom Brady trolling Donald Trump at the White House on my July bingo card.
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Hillary Layden retweeted
1 Jun 2021
Check out our latest methods paper. @HillaryLayden (with help from Kristy Stengel and @Nicky_eleuteri) describes how we use the dTAG system to identify the direct targets of transcription factors, from gRNA design to integration of genomic data sets. sciencedirect.com/science/ar…
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23 May 2021
Live footage of the third year of my PhD:
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Hillary Layden retweeted
21 May 2021
Congratulations to @DFBC_PedCare's A. Thomas Look, MD, on being awarded the 2021 Society of MSK award for his contributions to pediatric oncology: ms.spr.ly/6019VxWOd 🎉🎊👏
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Hillary Layden retweeted
15 May 2021
If you're fully vaccinated, the CDC recommends no longer validating your RNAseq with RT-qPCR
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