MD, PhD, Kidney Pathology, Institut Necker Enfants Malades, Paris, France
Joined November 2022
- Tweets 382
- Following 148
- Followers 138
- Likes 849
1 Photos and videos
Isnard Pierre retweeted
HNF1B as a central gatekeeper of tubular homeostasis dlvr.it/TSrQMr
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Isnard Pierre retweeted
Our latest paper just released. Congratulations to Ilaria, Charles and the entire team š¾š„³š„Oncogenic PIK3CA mutations shape an immunoregulatory microenvironment in mosaic overgrowth disorders academic.oup.com/pnasnexus/aā¦
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Check out our recent work on @NatureComms! Greatly appreciate my mentors and collaborators making this possible. We developed epi-Patho-DBiT, a unified platform that enables spatially resolved ATAC -seq or CUT&Tag analyses in FFPE tissues!
Excited to see this in print! Kudos to Haikuo, Bo, and the entire team including @MinaXu7 @yalepathology @zhou_jingtian @arcinstitute to explore this clinically relevant area of lymphoma transformation with truly innovative technology. @theNCI #HTAN
nature.com/articles/s41467-0ā¦
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Isnard Pierre retweeted
Apr 29
We generated a spatial atlas from 64 human kidney samples to define kidney niches and characterize
fibrosis through injured tubular microenvironments. We built a spatial immune atlas to study renal inflammation, uncovering a B cell-predominant immune microenvironment in DKD that correlated with disease severity and kidney function decline.
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Isnard Pierre retweeted
Apr 17
Congrats to @IsnardPierre1 and Marco Pontoglio HNF1B integrates signals in a feed-forward loop driving kidney disease progression | Happy to have contributed with Jon Levinsohn @ScienceMagazine science.org/doi/10.1126/scieā¦
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Apr 17
Thrilled to share our work! Immensely grateful to my incredible mentors, Fabiola and Marco, to all co-authors, and to Science for publishing and supporting our work !
science.org/doi/10.1126/scieā¦
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Isnard Pierre retweeted
Apr 15
šØ Our new paper just dropped !!! Proteomic risk score for early prediction of kidney disease progression in individuals with APOL1 high-risk genotypes nature.com/articles/s41591-0ā¦
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Nature research paper: Multiomics and deep learning dissect regulatory syntax in human development
go.nature.com/4cinsmn
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Isnard Pierre retweeted
Mar 27
I am very pleased with our latest paper, spearheaded by 3 incredibly talented first authors @chris_cowley14,@LFSoto12 and @SairajSajjath with @ElaineFuchsLab. Here we show that cells can remember past injury for a long time! science.org/doi/10.1126/scieā¦
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Isnard Pierre retweeted
Bx for AKI in a pt on checkpoint inhibitor: neutrophil rich tubulointerstitial nephritis. We would usually think pyelonephritis, high risk neutrophil rich variants of CKI inhibitor AIN have been characterized. pubmed.ncbi.nlm.nih.gov/4172ā¦ #renalpath #pathtwitter #nephrology
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Isnard Pierre retweeted
Mar 28
Whole-body molecular and cellular mapping of the laboratory mouse @CellCellPress @UChicagoPME
cell.com/cell/fulltext/S0092ā¦ šØš³šŗšø
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Isnard Pierre retweeted
What extraordinary news ā Iām extremely proud and honored.
Thank you @eshgsociety for this very prestigious award, which I share with the entire team. šš¾š„
The ESHG Award, ELPAG Award and the Mendel Lecturers of the #eshg2026 #hybridconference have talked to Mary Rice. Read the interviews and find out more about their backgrounds: 2026.eshg.org/speakers/speakā¦
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Isnard Pierre retweeted
Mar 11
Always special to write papers with @kidneyomicsamps, good friend, colleague, and neighbor (@broadinstitute & @TownofBrookline) jamanetwork.com/journals/jamā¦ @JAMANetworkOpen
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Isnard Pierre retweeted
Trimodal single-cell profiling of transcriptome, epigenome and 3D genome in complex tissues with scHiCAR go.nature.com/4rZqimf
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Feb 19
Thrilled to share our latest report: a challenging case of post-transplant graft dysfunction in a rare metabolic disorder:
kidney-international.org/artā¦
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Integrating single-nucleus barcoding with spatial transcriptomics via Stamp-seq to reveal immunotherapy response-enhancing functional modules in NSCLC
rdcu.be/e35I5
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Original Article: Sibeprenlimab in IgA Nephropathy ā Interim Analysis of a Phase 3 Trial (VISIONARY trial) nej.md/493Xtza
Editorial: Targeting the Pathogenesis of IgA Nephropathy ā A New Treatment Approach? nej.md/4too8hy
#Nephrology #Immunology
ALT Panel A: The percentage reduction of 24-hour urinary protein-to-creatinine ratio (UPCR) at month 9 is compared to baseline with the use of analysis of covariance (ANCOVA). Panel B: A line plot (generated from a mixed model for repeated measures) of spot UPCR results by visit as compared with baseline.
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Isnard Pierre retweeted
Jan 30
HumanBase: an interactive AI platform for human biology
nature.com/articles/s41592-0ā¦
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Isnard Pierre retweeted
19 Apr 2024
Single Cell Atlas: a single-cell multi-omics human cell encyclopedia genomebiology.biomedcentral.ā¦
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Isnard Pierre retweeted
Jan 16
Endothelial cellāreleased CD93 contributes to podocyte injury in idiopathic nephrotic syndrome | ā¦@ScienceTMā© ā¦@carafuentes_gā© science.org/doi/10.1126/scitā¦
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