Phages, bacteria, and pathogenicity islands. @NUSMedicine.
Joined October 2018
- Tweets 729
- Following 325
- Followers 692
- Likes 1,292
14 Photos and videos
Our latest! Phages no longer own transduction! Staph pathogenicity islands engage in lateral transduction and can also piggyback LT to drive genome hypermobility. Amazing work by @melchee92 @DrEsterSerrano @rbacigalupe @jrpenades @jrossfitz and others! authors.elsevier.com/a/1hW-h…
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JChen Lab retweeted
1 Aug 2025
Pleased to share our latest study @NatureComms. We show that the host metabolites fumarate and itaconate impose selective pressure on Staphylococcus aureus, driving its adaptation via the enzyme FumC. Grateful to all who contributed to this work!
nature.com/articles/s41467-0…
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JChen Lab retweeted
23 Jul 2025
A new encyclopedic review, for plasmid lovers:
academic.oup.com/nar/article…
We (Mapi, Eduardo and I) hope you like it!
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JChen Lab retweeted
7 Jul 2025
1/11 New #MRSA #Staph publication from Dr. Diane Boff a talented former postdoc co-mentored by the @TorresVJ_Lab and @DrShrutiNaik!
science.org/doi/10.1126/scia…
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JChen Lab retweeted
3 Mar 2025
Happy to share our new preprint describing prophage encoded anti-phage defense system,TERi, that targets the terminase complex of invading phages to inhibit DNA packaging. The system also encode self immunity proteins that protect the prophage.
biorxiv.org/content/biorxiv/…
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JChen Lab retweeted
12 Feb 2025
New mechanism of gene transfer! With @CostaT_Lab @CBRB_Imperial, cf-PICIs form tail-less elements that, once released, spread among different bacterial species by hijacking tails from various phages. More exciting news soon! shorturl.at/kRJqE
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JChen Lab retweeted
27 Jan 2025
We have a fully funded PhD scholarship for Aug 2025 intake.
If you are interested in joining our research group, please check the admission requirement on the website and contact us.
ntu.edu.sg/education/graduat…
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JChen Lab retweeted
28 Nov 2024
PhD projects at University of Leicester
Including three phage projects ....
With @MarthaClokie , and me. Including an iCASE project with Dr Abhinav Koyamangalath Vadakkepat , using cryoEM
le.ac.uk/study/research-degr…
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JChen Lab retweeted
21 Sep 2024
Pls share: Microbiology faculty position available at Texas A&M University.
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JChen Lab retweeted
21 Sep 2024
Our paper is finally out at Nature Microbiology. A team effort discovering Tailocin cell factories. Listeria monocytogenes bacteria produce and store ~6000 tailocins per cell in a remarkable way.
nature.com/articles/s41564-0…
21 Sep 2024
Happy to be part of this crazy team.
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JChen Lab retweeted
24 Jul 2024
1/7 Happy to share a new publication from the team spearheaded by @Keenan__Lacey published today in @ScienceAdvances. This project was started at @nyugrossman and was completed @StJudeResearch by @APickrum and A. Castellaw. science.org/doi/10.1126/scia…
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JChen Lab retweeted
22 May 2024
Our T6SS paper on TssA is now available @NatureComms
A publication marathon but so happy to see this accepted on my birthday
TssA is an intriguing protein providing specificity and fine tuning in T6SS assembly and firing.
Thank you so much for your brilliant work Selina et al
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JChen Lab retweeted
8 May 2024
Thank you to our excellent reviewers and Editor for helping us to improve significantly this review with their very useful comments!
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2 Apr 2024
Just missing April fool's, here is something that is no laughing matter:
nature.com/articles/s41564-0…
In @NatureMicrobiol, we describe how a prophage avoids autoimmunity from its own defence systems
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JChen Lab retweeted
2 Apr 2024
Led by @jakob_tr and @quiles_nuria, with @lasa_lab, we show that prophages utilise noncontiguous operons to balance immunity and autoimmunity. Our results underscore the essential fine regulation of these processes for prophages' life cycle development.
nature.com/articles/s41564-0…
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JChen Lab retweeted
6 Feb 2024
PhD student opening! We are collaborating with the team of David Johnson @EawagResearch to understand E. faecalis polymicrobial community assembly, interactions, and consequences for AMR and infection. Check out David's lab and work here: tinyurl.com/yrz3e2ae.
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JChen Lab retweeted
22 Jan 2024
Here's a little venture of mine🚀!
We've launched Scientifica Media, a scientific communication company that helps connect writers with relevant scientific backgrounds to deep tech companies!
Website: scientifica.media
Email: hello@scientifica.media
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Here's our latest endeavour into #AI-driven identification of synergistic drug combinations (out of half a million possible ones!) with broad spectrum activity against #MDR bacteria
Read more: onlinelibrary.wiley.com/doi/….
19 Jan 2024
A great group effort in identifying broad spectrum,new drug combinations against #MDR bacteria using #AI platform! onlinelibrary.wiley.com/doi/…. @thedeanh @YHGanLab @echow310 @OonTek1
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JChen Lab retweeted
3 Jan 2024
Well, I've been laid off from The Messenger.
If you're looking for an experienced reporter eager to take on complicated stories that explore the intersections of science, health and policy, please get in touch!
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