Urolithin A may be one of the most interesting supplements for mitochondrial aging
It activates mitophagy, the cellular cleanup process that removes damaged mitochondria before they drag down energy production, muscle function, and immune resilience
In older adults, 1,000 mg/day improved markers of immune aging, increasing CD8 T cells and natural killer cells while lowering markers of cellular senescence
In untrained athletes, the same dose boosted VO2 max by 10% beyond exercise alone, and improved hamstring strength in older adults by 10โ12% versus exercise alone