For 15 years, our work has shown that histone-modifying enzymes do more than just their catalytic jobs. They also have important non-catalytic roles. Dr. Zibo Zhao just published a great review on COMPASS family enhancer monomethylases and discusses how their loss creates new druggable vulnerabilities. nature.com/articles/s41568-0… Her findings are now in the clinic for treatment of cancers bearing MLL3/4-COMPASS mutations Fingers crossed! @NU_BMG_SQE @NUFeinbergMed @theNASciences @theNAMedicine @CellPressNews @ScienceMagazine @Nature @NatureCancer @MolecularCell @zhao_zibo

Really pleased to announce that Dr. Anish Thomas from the NCI -here at AACR 2026- will be joining the @LurieCancer Center as Medical Director of our Lung Cancer Program and Director of the new center for Cancer Metastasis. An exceptional physician scientist and leader.

LCRF is pleased to announce this year's 2025 Scientific Grant Program awards. Eleven awardees received a total $1.65 million in funding for new #LungCancer research. Read more about these scientists and the focus of their studies. LCRF.org/2025awards

Join us today for the BMG Seminar Speaker Dr. Christopher R. Vakoc! @ChrisVakoc Hosted by Dr. Lu Wang @LuWangLab #epigenetics #Cancer @NUFeinbergMed @NorthwesternMed @CSHL

The @LurieCancer (LCC) went thru competing renewal of NCI designation. For a 2nd time we got "exceptional" ranking. The NCI site visit team gave a "perfect exceptional" (equivalent to 10). LCC is one of few in the nation and the only one in IL to ever achieve exceptional status.

Read about some of our faculty’s effort at Northwestern Medicine Biochemistry and Molecular Genetics in developing targeted therapeutics towards human disease! @NUFeinbergMed @NU_BMG_SQE magazine.nm.org/2025/02/26/d…

Have you ever wondered why we have testis specific genes & what happens if their mechanism of silencing is misregulated in other cell types. Well, superb study by Bin Zhang in collaboration with @LuWangLab showed that such ectopic expression can drive cancer & can be targeted for therapeutics science.org/doi/10.1126/scia… @NUFeinbergMed @ScienceMagazine @ScienceAdvances @AACR @NU_BMG_SQE

Excited to share our latest work, showing GATA6 is a critical regulator in colorectal cancer and 3D genome organization. Led by Huijue, Zoe and thanks to our wonderful collaborators @LuWangLab and Dr. Guanyu Yang. @LurieCancer @NUFeinbergMed science.org/doi/10.1126/scia…

Nominations for Kimberly Prize in Biochemistry and Molecular Genetics for 2025 is now open! news.feinberg.northwestern.e… @NU_BMG_SQE @NUFeinbergMed @NorthwesternU @ASBMB @GeneticsGSA @aaas @the_asci

Join us today for the BMG Seminar Speaker Dr. Kapil Bhalla! Hosted by Dr. Lu Wang. @LuWangLab #epigenetics #research #AML @NUFeinbergMed @MDAndersonNews

Northwestern Medicine investigators have discovered that inhibiting a chromatin remodeling complex associated with a particular gene in small-cell #LungCancer cells may decrease cancer cell differentiation and tumor growth, per @NatureComms. spr.ly/6016wcdnI

Very excited to share our latest work on the function of POU2F3/POU2AF2 in mediating SWI/SNF-dependent transcription in small cell lung cancer nature.com/articles/s41467-0…

A wonderful Shilatifard's lab reunion dinner at @KeystoneSymp on Epigenetics and Cancer in Santa Fe! We missed our current and former colleagues whom were not at the meeting @NU_BMG_SQE @NUFeinbergMed @il_Piunti @ShimaaH_Soliman @bkcenik @LuWangLab @b_monz2 #KSCancerEpi24

Delighted to announce, for his fundamental discoveries with broad impact on biochemistry, biology & medicine, Dr. Craig Crews @CraigMCrews is the 2024 recipient of the #KimberlyPrize in Biochemistry and Molecular Genetics awarded by SQE @NUFeinbergMed bit.ly/47JFnyT

Northwestern University is now accepting nominations for its $250,000 Kimberly Prize in Biochemistry and Molecular Genetics. The annual prize will be awarded in 2024. Click the link for more information and where to nominate! #KimberlyPrize2024 news.feinberg.northwestern.e…

Online Now: Distinct layers of BRD4-PTEFb reveal bromodomain-independent function in transcriptional regulation dlvr.it/Ss4RQr

Investigators used #CRISPR to unravel the genes' role in tumor growth. Findings revealed that MLL3 and MLL4 knockout cells increased purine production, a crucial component for DNA and RNA. ➡️ spr.ly/6018OCHYO

Happy to share Dr. Zibo Zhao’s @zhao_zibo fantastic work in @jclinicalinvest demonstrating a link between epigenetics & metabolism for cancer therapy! This was a superb collaboration w/ Drs. Cao, Hashizume, Chandel and @bensahralab jci.org/articles/view/169993 youtu.be/lxF0J4fDWiA

Join us today for the BMG Seminar Series Speaker Jian Jin! Hosted by Lu Wang. @LuWangLab #Discovery #protein #epigenetics #medicalresearch @NUFeinbergMed @IcahnMountSinai @TischCancer

Four Feinberg Faculty Elected to American Academy of Arts and Sciences news.feinberg.northwestern.e…