All things genomics.

Joined May 2021
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@Mercerlab retweeted
BASE on the news! Check out the segment from @10NewsFirst on our recent clinical #mRNA manufacturing announcement featuring @Mercerlab1
BASE Facility, Australia's top mRNA provider, is creating a lab for clinical trial mRNA vaccines with $4.3M from the MRFF, $1M each from Sanofi, UQ, and $250K from the Queensland Government. The project ensures end-to-end capabilities for mRNA vaccine development. Watch more 👇
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@Mercerlab retweeted
6 Nov 2023
A dedicated lab will produce mRNA for clinical trials @AIBNatUQ's BASE facility. The next generation of mRNA vaccines and therapies will be built in Queensland, thanks to $4.3m from @healthgovau, #MRFF and contributions from #UQ @sanofi @QldGov👏 More: uq.au/BASE
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@Mercerlab retweeted
Exciting news! 🌟 @BASEmRNA, The University of Queensland, partners with @sanofi (TSH) and the Australian Government (MRFF) to advance #mRNA manufacturing for clinical trials, bolstering our capabilities to meet the surging demand. 💉🔬 stories.uq.edu.au/news/2023/…
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@Mercerlab retweeted
Thrilled at the announcement of our successful MRFF grant to establish mRNA manufacture @BASEmRNA for early-stage clinical trials of new mRNA vaccines and therapies. Thanks to @sanofi, @UQ_News and the Queensland Government for their support for this effort.
6 Nov 2023
A dedicated lab will produce mRNA for clinical trials @AIBNatUQ's BASE facility. The next generation of mRNA vaccines and therapies will be built in Queensland, thanks to $4.3m from @healthgovau, #MRFF and contributions from #UQ @sanofi @QldGov👏 More: uq.au/BASE
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@Mercerlab retweeted
Are you at #AusBiotech23 conference in Brisbane? Don't miss Today's (Friday 3rd Nov) session at 12:30 pm. BASE Deputy Director @SethCheetham  will give a talk on "accelerated mRNA manufacture from synthetic DNA templates" at Breakout Room 1. See you soon!
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@Mercerlab retweeted
Our Director A/Prof Tim Mercer talked about "mRNA Therapeutics’ Landscape" at The Bridge Program Symposium 2023. A lot of excitement in the mRNA space! #mRNA #therapeutics #manufacuring #innovation
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@Mercerlab retweeted
We're at AusBiotech (1-3 Nov)! If you haven't talked to us yesterday, welcome to visit the BASE mRNA Facility Booth (#84). Looking forward to connecting and discussing the latest innovations in mRNA research and manufacture. #AusBiotech #mRNA #NonforProfit #ResearchService
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25 Oct 2023
Great to see an update on @nanopore only bacterial assemblies from @rrwick, using the latest base-caller models. tl/dr: use sup if you can afford it computationally.
24 Oct 2023
New blog post: rrwick.github.io/2023/10/24/… I revisit the question of ONT-only accuracy for bacterial genomes, and things have improved a lot since I last looked at this about six months ago!
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@Mercerlab retweeted
Last week, we welcomed Louise Talbot from the Department of Industry, Science, and Resources at #BASE mRNA Facility. We are delighted to demonstrate our advanced mRNA #manufacturing, ONT #sequencing tech for mRNA vaccines, and a #roundtable about mRNA research & innovation at UQ
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@Mercerlab retweeted
11 Oct 2023
Nature research paper: Genotyping, sequencing and analysis of 140,000 adults from Mexico City go.nature.com/45lE0UY

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@Mercerlab retweeted
Long-read sequencing tools can capture the full picture of genomes and transcriptomes. An Analysis assesses the performance of long-read RNA sequencing analysis tools including isoform detection and differential expression analysis workflows. nature.com/articles/s41592-0…
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For anyone after a Cliff notes version of our @nanopore sequencing test for mRNA vaccines made at @BASEmRNA, check out our “behind the paper” blog post.
Curious about our use of @oxfordnanopore Technologies sequencing for mRNA vaccine quality testing at @BASEmRNA ? Check out the 'behind the paper' blog in Nature Genetics and Genomics Community written by @ Helen Gunter at @Mercerlab1 : gengenocommunity.springernat…
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@Mercerlab retweeted
BREAKING NEWS The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin KarikĂł and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
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@Mercerlab retweeted
A sequencing protocol with supporting software for quality assessment of mRNA vaccines @mercerlab1, @BASEmrna and @AIBNatUQ #BiotechNatureComms nature.com/articles/s41467-0…

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29 Sep 2023
Laura from the @SethCheetham group and @BASEmRNA is newly initiated in making @nanopore cDNA sequencing libraries. Look at all that green from a >1 year old flow cell! Super impressive first libraries Laura!
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@Mercerlab retweeted
VAX-seq offered a sensitive and quantitative assessment of mRNA characteristics, and also enabled real-time identification of antisense RNA and messenger RNA integrity, allowing for swift testing lasting a few hours post-manufacture. Read more: news-medical.net/news/202309…
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@Mercerlab retweeted
Real-time integrity measurement of individual #mRNA vaccine molecules is now possible thanks to a @BASEmRNA @nanopore partnership. “Nanopore sequencing is the only sensing tech that can read native RNA in real time, making it an essential part of the toolkit" - @gordon_sanghera
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21 Sep 2023
Thank you @nanopore! We’re excited to partner with you to transform mRNA vaccine quality analysis! @BASEmRNA
The BASE facility at @UQ_News and @nanopore partner to improve the analysis of mRNA vaccines. Read how the approach promises to simplify and better ensure the quality of manufactured mRNA-based vaccines and therapeutics worldwide. Read more: bit.ly/3RtH7a0
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21 Sep 2023
Have you ever wondered what’s in an mRNA vaccine? We have developed an RNA sequencing based test that measures mRNA vaccine quality on a single molecule level, in collaboration with @BASEmRNA and @GIH_UQ! Exciting times! @nanopore @AIBNatUQ nature.com/articles/s41467-0…

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