@OveracreLab profile picture
Overacre Lab @OveracreLab

Assistant Professor @UPMCHillmanCC | @DamonRunyon Dale Frey Scientist | microbiome & immunotherapy | follow your gut | she/her/hers | views are my own

Joined April 2010
  • Tweets 1,923
  • Following 1,267
  • Followers 1,568
270 Photos and videos
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Overacre Lab@OveracreLab
31 Jul 2025
I am thrilled to finally share my lab's first paper showing that sucralose consumption reduces immunotherapy efficacy in cancer, published NOW in @CD_AACR ! Let's break it down. 1/n aacrjournals.org/cancerdisco…

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Overacre Lab retweeted
Society for Immunotherapy of Cancer
@sitcancer
Jun 3
Announcing the 2026 #SITC election results! Thank you to all of the candidates for their interest in serving the society, and to the members who voted. sitcancer.org/get-involved/2… #immunotherapy #cancerIO
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Delgoffe Lab@DelgoffeLab
Apr 29
Dearest gentle reader, we are delighted to announce a new story from our lab published in @Nature describing how a meal's systemic metabolic changes are interpreted by your immune system to enhance adaptive immunity. A thread 1/ nature.com/articles/s41586-0…

Postprandial lipid metabolism durably enhances T cell immunity

Nature - Experiments in mice and humans show enhancement of T cell function following fasting and refeeding, caused by persistent immunometabolic reprogramming, with potential implications for...

nature.com
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UPMC Hillman Cancer Center@UPMCHillmanCC
Apr 18
Congratulations Dr. Finn, an amazing immunologist who continues her research on vaccines at UPMC Hillman & the University of Pittsburgh! @pitt_immunology @PittHealthSci @UPMCnews @UPMCPhysicianEd
Tullia Bruno, PhD@BcellBruno
Apr 18
It was an absolute honor to introduce Dr. Olja Finn as she received the AAI Distinguished Mentor Award @ImmunologyAAI this year. Olja, you are a pioneer in science, mentorship, and life. 👏💕💜 #IMMUNOLOGY2026 @UPMCHillmanCC @PittTweet
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Pitt Department of Immunology@pitt_immunology
Apr 16
Congratulations to Drs. Dario Vignali @Vignali_Lab and Sarah Gaffen (@PittDeptofMed, @PittRheum) on being recognized as 2026 Distinguished fellows yesterday at @ImmunologyAAI #IMMUNOLOGY2026!
Sarah Gaffen and Dario Vignali holding their American Association of Immunologists (AAI) Distinguished Fellow of 2026 awards at the AAI meeting in Boston.

ALT Sarah Gaffen and Dario Vignali holding their American Association of Immunologists (AAI) Distinguished Fellow of 2026 awards at the AAI meeting in Boston.

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Had a fantastic time at the Case CCC Microbiome Conference! Thanks for the invite @nataliesilvermd - what an inspiring event!
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A belated but very happy 4th birthday to the lab 🎉 so thankful for such an awesome crew! Here’s to many more years of science and fun.
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Pitt Department of Immunology@pitt_immunology
Apr 9
Diet soda could be sabotaging cancer treatment. Exercise could be boosting it. It all comes down to the gut microbiome. @PittHealthSci and @UPMCHillmanCC researchers are figuring out how to harness gut bacteria and protists to improve cancer outcomes: immunology.pitt.edu/news/tru…
Illustration of a gut filled with microorganisms with a background of cancer and immune cells

ALT Illustration of a gut filled with microorganisms with a background of cancer and immune cells
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Pitt Department of Immunology@pitt_immunology
Apr 8
Next up in our trainee spotlight series is Katelyn Wolfgang (@Kate_Wolfgang), a graduate student in the @OveracreLab who studies how a commensal gut bacterium drives the formation of tertiary lymphoid structures in the colon: immunology.pitt.edu/news/tra…
Trainee Spotlight graphic with photo of Katelyn Wolfgang, graduate student in Abby Overacre's lab.

ALT Trainee Spotlight graphic with photo of Katelyn Wolfgang, graduate student in Abby Overacre's lab.
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Overacre Lab retweeted
Iwijn De Vlaminck@IwijnDeVlaminck
Mar 9
New paper in @NatureMicrobiol. Spatial RNA mapping of microbiome and host. In situ polyadenylation is the key idea. More to come on this. Thank you @NIH and @weandmecfs. nature.com/articles/s41564-0…
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Honored to be part of this @UPMC Cancer Prevention and Survivorship Symposium today!
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An incredible study, congrats all!
Waggoner Lab@LabWaggoner
Mar 6
Spatial transcriptomics maps host–gut microbiome biogeography at high resolution nature.com/articles/s41564-0… @NatureMicrobiol @dwmckellar @ntekasi @IwijnDeVlaminck @Cornell
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Congrats to @jessica_jana_ and Kelsey Ertwine for receiving @ImmunologyAAI awards at @TRCCC1998 this year!!
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We also had great representation by @Kate_Wolfgang_ and @sadhanabom in the lab!
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The lab had a great time @TRCCC1998 this year!
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Congrats to @ItzDipyaman for being selected for a SITC sponsored talk where he talked about Tregs and irAEs!
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I got to share some new work in the lab during the Microbiome Emerging Science Working Group
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Honored to be featured by @DamonRunyon this year! damonrunyon.org/discovery/ar…
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Love being a part of this! Thanks for including me @JExpMed !
Lucie Van Emmenis@Lucie_JExpMed
24 Dec 2025
As 2025 is drawing to a close, @JExpMed would like to highlight all of the women who have contributed to the #WomenInSTEM #Viewpoint series over the last 3 years! Learn more about their scientific journeys on the path to independence here 👉 tinyurl.com/2wrxk4mk
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So thankful for this crew! Missing a couple folks, but we got out of the lab for some cheer tonight!
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Incredibly proud PI today after @Pitt_PMI day! My three incredible students presented their work and helped to organize an awesome event! @jess_jana_ @Kate_Wolfgang_
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