Joined June 2012
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Excited to share our new paper in @FEBSJournal! With @OndrejKuda & @FedorovaLab we show how LDs reshape the lipidome of PUFA-exposed cells & shift function within the same cell, revealing a context-dependent role in ferroptosis. Congrats Ana & @Lejaperne! shorturl.at/TyRl1
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A new review from the lab on #LipidDroplet heterogeneity in Current Opinion in Cell Biology. Big thanks to Philippe Chavrier and Chris Fromme for organizing an exciting #Membrane Trafficking special issue! sciencedirect.com/science/ar…

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Toni Petan retweeted
The danger of reasoning by analogy: "The behavior of things on a very tiny scale is simply different. (Atoms) do not behave just like particles. The do not behave just like waves. Atoms do not behave like weights hanging on a spring and oscillating. Nor do they behave like miniature representations of the solar system with little planets going around in orbit. Nor does it appear to be like a cloud or fog of some sort surrounding the nucleus. It behaves like nothing you've seen before." Likewise, the cell is not a deterministic machine or factory. I think I can safely say that nobody understands the cell.
“I think I can safely say that nobody understands quantum mechanics.” - Richard Feynman (1964 Cornell Lecture)
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Toni Petan retweeted
Artificial intelligence is not replacing human intuition in maths and physics, but reimagining how questions are asked, explored and understood go.nature.com/4aESYuz
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Marjana Ndoci, @DeshwalSoni et al. show that #mitochondria prioritize survival over safety: when resources are low, they stop exporting Coenzyme Q to keep respiration running, at the cost of antioxidant protection. hubs.la/Q04kwgfH0 #CellMetabolism #Organelles
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DGAT-driven futile lipid cycling has a pronounced, yet concealed, thermogenic function dlvr.it/TSr75k
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Please re-post! Time is almost up to register for the 2026 FASEB Lipid Droplet Meeting. Abstracts are due May 31, 2026. See link below, and join us for an amazing SRC lipid meeting July 26-30! #LipidSRC events.faseb.org/event/Lipid…
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📖FOS New Mini-Review! “On the lethal mechanism of class III ferroptosis inducers” by Prof. Scott J. Dixon from @Stanford. Check to see why FIN56 causes ferroptosis but its analogs don’t. 🔗: sciexplor.com/fos/articles/f… #ferroptosis #Science #academic #cell
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Toni Petan retweeted
Fasting opens a metabolic window that favors anti-tumor immunity dlvr.it/TSWY8J
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Great to see this Spotlight article in Trends in Cell Biology highlighting our recent identification of a lipid droplet quality control pathway in which FSP1 protects PUFA-rich neutral lipids from peroxidation, thereby suppressing ferroptosis. cell.com/trends/cell-biology…
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You do not want to miss the 2026 FASEB #LipidDroplet conference! Abstracts are due May 31. Travel awards are available for trainees 👇
Summer is approaching & so is the 2026 Lipid Droplets: From Mechanisms to Disease FASEB SRC (July 26-30 in Scottsdale, AZ)! Interested in lipids? Join this amazing summer research conference! Abstracts due May 31, Early registration June 14. events.faseb.org/event/Lipid…
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Apr 29
We are looking forward to this presentation by our colleague Dr Duško Lainšček as part of the #symposium we are organising in collaboration with the #CFGBC. Don't miss it Link: cfgbc.mf.uni-lj.si/events/20…

Meet invited speaker Dr Duško Lainšček at the GeneH & 21st CFGBC Scientific Symposium in Ljubljana. He will present: “AAV9-Mediated Gene Replacement Therapy for CTNNB1-Related Neurodevelopmental Disorder.” Learn more: shorturl.at/rBCS8 #GeneH #CFGBC #GeneTherapy #CTNNB1
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New! Online now: DGAT-driven futile lipid cycling has a pronounced, yet concealed, thermogenic function dlvr.it/TS9Sb1
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💥New Article in FOS! Ferroptosis surveillance: Insights from in vivo contexts by Dr. Thales Papagiannakopoulos @ThalesPapaG team and Dr. Jessalyn M. Ubellacker from @HarvardChanSPH Please check the link🔗: sciexplor.com/articles/fos.2… #ferroptosis #cell #scienceresearch
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Thanks to @NatureSMB for publishing a "Research Briefing" on our recent work, highlighting the discoveries and providing context on the story behind our research into how vitamin B2 metabolism regulates FSP1 stability to suppress ferroptosis.
New online! FAD-dependent stabilization of FSP1 promotes ferroptosis resistance dlvr.it/TRSYqP
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1/3 Thrilled to see our paper led by Kirandeep Deol is out! We used CRISPR screens to uncover regulators of the ferroptosis suppressor FSP1. key discovery: vitamin B2 metabolism stabilizes FSP1 via FAD, revealing a new way vitamins regulate ferroptosis. nature.com/articles/s41594-0…
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Online Now: Targeting mitochondrial metabolism with combined metabolic activators dlvr.it/TRLrH5 #trends #endocrinology #metabolism
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"Short-term fasting induces intratumoral accumulation of isoleucine, which reconfigures CD8 T cell epigenetic programs and phospholipid remodeling, thereby licensing enhanced anti-tumor capacity."
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