Joined December 2021
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We are pleased to share our paper "Mechanistic insights into Lin28-dependent oligo-uridylylation of pre-let-7 by TUT4" academic.oup.com/nar/article…
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Congrats, Professor Suga.
Professor Hiroaki Suga won the Antonio Feltrinelli International Prize in Chemistry | The University of Tokyo u-tokyo.ac.jp/focus/en/artic…
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Nature research paper: Substrate selectivity of the human RNA m5C methyltransferase NSUN2
go.nature.com/4u06VdG
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Visiting Kagoshima for the first time for the International Conference on Plant Mitochondrial Biology (ICPMB2026). Excited for great science and grateful to the organizers for hosting such a wonderful meeting!!
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Kozo Tomita Lab: RNA Biology retweeted
May 13
Excited to share our work uncovering SNOR, a ribosome-associated factor that promotes translation restart after dormancy published in Nature!! This was, as usual, a wonderful collaborative effort between our group @UVA and @simonemattei @EMBLHeidelberg
nature.com/articles/s41586-0…
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Kozo Tomita Lab: RNA Biology retweeted
The regulation, function and disease relevance of cytoplasmic tRNAs nature.com/articles/s41580-0… Review: tRNAs: genomic organization, spatiotemporal expression, QC pathways, tissue-specific abundance, stress signalling, and emerging therapeutic strategies for translation defects
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Kozo Tomita Lab: RNA Biology retweeted
Apr 23
For decades, biology textbooks have enshrined a simple rule: DNA is made by copying a template. After one enzyme unzips a DNA double helix into separate strands, another called a polymerase builds a complementary sequence, base by base, for each strand. Presto: two copies of the original DNA.
But new research into how bacteria defend themselves from viruses now shows this synthesis rule isn’t absolute.
Now, a team describes a bacterial enzyme that synthesizes DNA without a nucleic acid template, using its own structure as a guide.
Learn more: scim.ag/4tTc5IA @NewsfromScience
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Visited Kumamoto University for a seminar. Many thanks to Prof. Tomizawa and Dr. Chujo, @RNAbiker for the invitation. I truly enjoye the opportunity to share and discuss science—it was a great time.
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Kozo Tomita Lab: RNA Biology retweeted
#MachineLearning models discover thousands of bacterial immune systems, according to two new papers in Science.
Together, these studies reveal that bacterial immunity is far more extensive than previously appreciated, and highlight how such discoveries can inspire powerful biotechnologies.
📄: scim.ag/3Qm3IXs
📄: scim.ag/47MowgS
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Cherry blossoms at Kashiwanoha Park yesterday morning, on my way to the lab.
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Muscolino, E., Puig-Torrents, M., Buigues Bisquert, J. et al. Coronaviruses reprogram the tRNA epitranscriptome to favor viral protein expression. Nat Commun (2026). doi.org/10.1038/s41467-026-6…
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Structural basis of double-stranded RNA recognition by the J2 monoclonal antibody. Nat Commun 17, 635 (2026). doi.org/10.1038/s41467-025-6…
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Kozo Tomita Lab: RNA Biology retweeted
Jan 19
An engineered UGA suppressor tRNA gene for disease-agnostic AAV delivery: nature.com/articles/s41587-0…
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Kozo Tomita Lab: RNA Biology retweeted
The barrel-shaped structures found by the thousands in most animal cells are one of biology’s biggest mysteries. But although researchers haven’t figured out the function of these “vaults,” they now report a new use for the puzzling particles.
Learn more: scim.ag/3NKZXJQ
ALT Two panel graphic showing new method for tracking gene activity.
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Kozo Tomita Lab: RNA Biology retweeted
Jan 13
[プレスリリース] がん抑制マイクロRNA生合成を制御する分子機構を解明―――新たな創薬技術基盤の提示に貢献――新領域創成科学研究科
u-tokyo.ac.jp/focus/ja/press…
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Kozo Tomita Lab: RNA Biology retweeted
Jan 12
Don’t forget protein synthesis! Mitochondria of cancer cells import glutamine to fuel metabolism and to charge tRNAs for translation dlvr.it/TQJhgY
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