Joined July 2015
1,116 Photos and videos
Pinned Tweet
Five years ago, in October 2020, my institute appointed me to a full professorship. On this occasion, I select 10 representative research papers we published in the past 5 years. It's been an absolute privilege to work with my super-talented, industrious, and fearless students.
Happy to share that after a long-drawn-out process, my institute has removed the first word of my academic rank. First time in my academic life, I have got a "one-word" description of my position. I thank my incredible students for their contributions and my family for support.😀
10
8
406
42,515
Samrat Mukhopadhyay retweeted
Excited to share that our preprint 'RNA reinforces condensate nucleation on chromatin to amplify oncogenic transcription' is now online @MolecularCell cell.com/molecular-cell/full… @PennMedCSO @PennCancer @PennEpiInst
(1/n) Excited to share our new preprint! We uncover that RNA actively promotes nucleation and function of pathogenic condensates, amplifying locus-specific oncogenic transcription and promoting tumorigenesis. #epigenetics #condensates #cancer #RNA biorxiv.org/content/10.1101/…
6
17
85
11,709
Samrat Mukhopadhyay retweeted
Our TEAD1 condensate paper is now online at Nature Cell Biology! TEAD1, despite being a transcription factor, forms condensates at the heterochromatin. We found that it actually served as depots to sequester excess TEAD1. Nature is full of surprises! nature.com/articles/s41556-0…
6
31
194
10,656
Samrat Mukhopadhyay retweeted
This is an incredibly useful resource for anyone interested in Fluorescence.
After many requests, I've decided to share a few lectures from my Fluorescence in Biology course, which I've been teaching at IISER Mohali. This is the first lecture (recorded in Jan 2022) on the basics of fluorescence. I hope this is useful to students. youtu.be/716zUbp-81A?si=tT4i…
1
1
17
2,309
Samrat Mukhopadhyay retweeted
Students who are highly interested in fluorescence spectroscopy should watch these lectures taught by one of the finest teachers, @SamratLabMohali, now available on YouTube. Earlier, the BIO611 course was accessible only to @IISERMohali students, but it is now free to watch.
After many requests, I've decided to share a few lectures from my Fluorescence in Biology course, which I've been teaching at IISER Mohali. This is the first lecture (recorded in Jan 2022) on the basics of fluorescence. I hope this is useful to students. youtu.be/716zUbp-81A?si=tT4i…
1
2
15
2,520
After many requests, I've decided to share a few lectures from my Fluorescence in Biology course, which I've been teaching at IISER Mohali. This is the first lecture (recorded in Jan 2022) on the basics of fluorescence. I hope this is useful to students. youtu.be/716zUbp-81A?si=tT4i…
5
16
143
15,469
This is the second lecture on the basics of fluorescence, which explains the processes of excitation and emission, vibrational/solvent relaxation, Stokes shift, quantum yield, lifetime, etc., using the Jablonski diagram. Hope this lecture is useful. youtube.com/watch?v=S_lBpwhl…
1
14
1,190
This is the second lecture on the basics of fluorescence, which explains the processes of excitation and emission, vibrational/solvent relaxation, Stokes shift, quantum yield, lifetime, etc., using the Jablonski diagram. Hope this lecture is useful. youtube.com/watch?v=S_lBpwhl…
After many requests, I've decided to share a few lectures from my Fluorescence in Biology course, which I've been teaching at IISER Mohali. This is the first lecture (recorded in Jan 2022) on the basics of fluorescence. I hope this is useful to students. youtu.be/716zUbp-81A?si=tT4i…
17
2,069
Every June reminds me of my cliff-hanging life-changing journey to @IIScBangalore (June 1997), almost a fairy tale. I narrated this story in June 2022 on the occasion of 25 years (now 29 years ago). I'm quoting it again if some youngsters want to draw inspiration from my story.👇
25 years ago: June 1997. I was selected for the highly competitive & coveted integrated PhD (MS PhD) program at the Indian Institute of Science (IISc) Bangalore. My life changed forever. Whatever little I have done, I owe it to IISc. I narrate a fascinating story. Read on (1/n)
50
2,061
Thousandfold Expansion Microscopy (1000ExM) is going to revolutionize biological imaging (a billion-fold expansion in volume), entering the Ångstrom-scale resolution in optical imaging. Exciting times ahead! Read the preprint: biorxiv.org/content/10.64898…

Hello world, meet 1,000× Expansion Microscopy. 1,000,000,000× expansion by volume! A gel that starts at a few centimeters will then expand to the volume of an Olympic swimming pool. biorxiv.org/content/10.64898… In our new bioRxiv preprint, work carried out between MIT and UMG, led by Helena Hu in collaboration with scientists from the labs of @eboyden3 Ed Boyden, Silvio Rizzoli, and myself, we present Thousandfold Expansion Microscopy. By enlarging biological specimens across multiple rounds of expansion, molecular-scale features, as small as the distances between adjacent amino acids, can be visualized with conventional optical microscopes. Democratizing super-resolution microscopy.
1
31
4,385
A must-read piece, "The genie of synthetic biology is out, and with it comes power and peril" by @kvijayraghavan. I will use this article in my freshman BIO-101 course next semester. I should use the brilliant Oppenheimer quote, "See things not as they are, but as they might be."
Replying to @kvijayraghavan
This is a summary that does not quote from the piece. Do read the piece too. As always, your critical feedback and views are much appreciated. A link to a PDF acrobat.adobe.com/id/urn:aai…
17
1,501
I've been invited to join the Executive Committee of the Society of Biological Chemists (India), headquartered at the Indian Institute of Science, Bangalore. Founded in 1930, SBC(I) has been playing a crucial role for ~100 years. Looking forward to working with SBC(I) colleagues.
12
4
115
4,403
Happy to share our latest preprint. biorxiv.org/content/10.64898…
5
16
79
4,229
Samrat Mukhopadhyay retweeted
Truly grateful to @SamratLabMohali and @EMBLEvents for the opportunity, and @ANRFIndia for the travel grant to attend the EMBO Symposium at EMBL Heidelberg, Germany. I look forward to presenting my work on nucleolar condensates and engaging with the community! #EESPhaseSeparation
Dr. Arpita Singh @Arpita195 (National Postdoctoral Fellow in our lab) is attending an EMBO Symposium on "Cellular Mechanisms Driven by Phase Separation" starting today at EMBL Heidelberg, Germany. She will present her new results on nucleolar condensates. embl.org/about/info/course-a…
1
3
19
2,432
Dr. Arpita Singh @Arpita195 (National Postdoctoral Fellow in our lab) is attending an EMBO Symposium on "Cellular Mechanisms Driven by Phase Separation" starting today at EMBL Heidelberg, Germany. She will present her new results on nucleolar condensates. embl.org/about/info/course-a…
1
36
3,975
Samrat Mukhopadhyay retweeted
Recently, I completed the BIO412 (Bio-Physics Lab) course taught by @SamratLabMohali. These are some notes that I took during his lectures. This was my second time being taught by him , the first one was during my sophomore year (Chemical Biology) .
2
6
64
6,472
I truly enjoyed teaching the biophysics lab to our 4th-year biology majors in the spring semester. A student, Anshika Chakrabortty, sent me class notes she took in my classes. I'm sharing a few pages, with her permission, on the basics of fluorescence. Happy #FluorescenceFriday!
2
2
122
4,359
I'm so delighted to learn that my postdoc alma mater, @ScrippsResearch, is ranked #1 in biology graduate programs in the US. Jamie Williamson announced this news just before the Front Row lecture by the Scripps President, Peter Schultz. Watch the event: frontrow.scripps.edu/lecture…
Biomedical research has produced many of the discoveries that underpin modern medicine, but turning those findings into real treatments—and maintaining the research enterprise behind them—requires new approaches. In last week's free Front Row lecture, Scripps Research President and CEO Peter Schultz described how the institute is building a nonprofit model that brings basic science and translational research together to move promising ideas toward medicines more effectively. He highlighted advances spanning aging, artificial intelligence (AI) and global health while also making the case for a more sustainable way to support innovative science. Watch the full lecture now at ow.ly/qA6Q50YQNMv #ScrippsResearch #Nonprofit #Biomedial #Research #Science #Biotech
33
1,690
Samrat Mukhopadhyay retweeted
On the occasion of Mother's Day, I share my sister's rice ceremony photo (1980). My mother Namita Mukhopadhyay studied Arts & Law & worked as a high-ranking official for Indian Railways. She supported my scientific pursuit when everyone wanted me to study engineering or medicine.
4
2
207
5,668