Pediatric Hematologist/Oncologist/BMT @Cleveland Clinic Children's; opinions my own
Joined October 2012
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- Followers 552
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24 Photos and videos
seth rotz retweeted
24 Jan 2025
Thank you, everyone, for attending our January 2025 design session! We're thrilled to have our project picked and can't wait to see you all this summer. Special shoutout to our Engraft Olympic champions, “You down with A-P-P?” — stellar teamwork! 🎉
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seth rotz retweeted
26 Dec 2024
🚨PublicationAlert🚨 How I Treat Sickle Cell Disease with Gene Therapy, published online (authors.elsevier.com/a/1kKhU… ) and in print in @BloodJournal
Many thanks to @DrAlexisThompsn @jkw4444 @LakshmananKris7 @shal34982692 @BMTriplettMD and @allistair_2001 for their inputs 🙏
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seth rotz retweeted
11 Dec 2024
Tom Hamilton, the radio announcer for #Indians / #Guardians games for 35 years and counting on Wednesday was selected by the Baseball Hall Fame for induction in Cooperstown this summer. His emotional reaction is priceless.
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seth rotz retweeted
9 Dec 2024
Fred Hutch’s @msorror presents the latest findings on a new health assessment model called CHARM, which helps health care teams predict which patients will survive transplantation. #ASH24 fredhutch.org/en/news/center…
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Original Article: Blinatumomab in Standard-Risk B-Cell Acute Lymphoblastic Leukemia in Children (AALL1731) nej.md/49CVkc1
#ASH24 | @ASH_hematology
ALT The comparisons of 3-year disease-free survival (Panel A), overall survival (Panel B), and cumulative incidence of relapse (Panel C) in the overall randomized cohort, among patients who underwent randomization and had an average risk of relapse, and among those who underwent randomization and had a high risk of relapse.
ALT Forest plot of disease-free survival in various subgroups as assessed by restricted mean survival time estimates.
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seth rotz retweeted
8 Dec 2024
Impressive results about Exa-Cel in TDT from @VertexPharma at # ASH
- 54 patients
- 98% (53/54) had achieved Transfusion free x12 months
- the remaining patient is free of RBC Tx for at least 8 months
Similar results about safety and efficacy in #SCD
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seth rotz retweeted
8 Dec 2024
BEACON study initial data @BeamForAll IN #AS24
- BASE editing in Hgb1/2 for #SCD :7 patients
- less collection cycles
- faster engraftment in ANC (17 days) and PLT (19 days)
- one death
- high level of hgb F (>60%) with improvement in total hemoglobin and less hemolysis
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seth rotz retweeted
14 Nov 2024
1/ This is the next chapter of a story about courageous patients and their families, of multidisciplinary teamwork, and hard-fought steps forward to effective therapy for #DIPG #DMG, a universally lethal cancer of the brain and spinal cord. 🧵nature.com/articles/s41586-0…
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seth rotz retweeted
26 Nov 2024
No new safety concerns were identified with daratumumab treatment in children and young adults with B-cell ALL or T-cell ALL/LL. ow.ly/C42E50UckmH #lymphoidneoplasia
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seth rotz retweeted
23 Nov 2024
Leveraging Oncology Treatments for Vascular Anomalies my.clevelandclinic.org/podca… via @clevelandclinic
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seth rotz retweeted
16 Nov 2024
Menin inhibitor approved for relapsed or refractory ALL with (KMT2A) translocation in adult and pediatric patients 1 year and older.
FDA approves revumenib for relapsed or refractory acute leukemia with a KMT2A translocation fda.gov/drugs/resources-info…
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seth rotz retweeted
10 Nov 2024
Key factors increasing the chance of pregnancy were younger age at HCT, nonmalignant disease, no TBI or dose <8 Gy and RIC/NMA conditioning
@BloodJournal - Hope for motherhood: pregnancy after allogeneic #BMT ashpublications.org/blood/ar…
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seth rotz retweeted
10 Nov 2024
Engraft was awarded the DENNIS CONFER INNOVATE
AWARD from the NMDP. Congratulations, Engraft! | The ONE Forum 2024 youtu.be/mfr2o878Vjo?si=oasW… via @YouTube
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seth rotz retweeted
13 Oct 2024
Good morning! Mile 18 is in the book - 6 miles to go ... #The24in24
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seth rotz retweeted
20 Sep 2024
Congratulations to Dr. Kate Eshleman for receiving the enterprise “Caregiver Philanthropy Award” 🎉
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seth rotz retweeted
13 Sep 2024
I am speechless this afternoon .. Thank you 🙏 #brunswick city and #Medina county for amazing #Trike&Bike @bikeVeloSano to help us fund #ChildhoodCancer #Research @CleClinicKids
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seth rotz retweeted
6 Sep 2024
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seth rotz retweeted
3 Sep 2024
What happens when a virologist develops recurrence of her breast cancer? She injects two viruses into the tumour to shrink it. This is either crazy or genius and I can not decide which. Apparently self experimentation does not require ethics review! tinyurl.com/2phe4cc4 #cancer #breastcancer
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seth rotz retweeted
2 Sep 2024
Today is the 1st day of #SickleCellAwarenessMonth
So many awareness angles but let’s not forget that this is arguably the most neglected #GlobalHealth problem
A baby with SCD is born every MINUTE
Awareness is good but we need so much action.
Who’s here for it?
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