Microbiologist, works on Staphylococcus aureus, quorum sensing, evolution and virulence. Views are my own. I don't always wear the flat cap.
Joined June 2013
- Tweets 1,032
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- Followers 414
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11 Photos and videos
Pinned Tweet
6 Jan 2025
Staphylococcus aureus gliding comets: formation and observation - new observations of the S. aureus comets and how to get the assay to work biorxiv.org/content/10.1101/…
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30 Oct 2025
Mycobacterium smegmatis Expands Across Surfaces by Hydraulic Sliding - Environmental Microbiology Reports enviromicro-journals.onlinel…... - Our new paper is out!
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30 Oct 2025
M. smegmatis uses new types of biofilm to enclose a liquid core and expand outwards in a weird new way.
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6 Jan 2025
Staphylococcus aureus gliding comets: formation and observation - new observations of the S. aureus comets and how to get the assay to work biorxiv.org/content/10.1101/…
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6 Jan 2025
Artistic interpetation of a fluorescently tagged comet... Happy to talk to people about the S. aureus comet motility assay, if they need help with it etc
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6 Jan 2025
S. aureus organises itself differently in motile comet tips and can go uphill
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Eric Pollitt retweeted
24 Jul 2024
Scientists present a soft #biorobotic heart to assess the feasibility and safety of new valve designs and #biomaterials to correct #TetralogyofFallot, offering a reliable model to inform reconstructive heart surgery. @ScienceTM scim.ag/7MM
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Eric Pollitt retweeted
22 Jul 2024
Study in #zebrafish shows the #heartbeat's mechanical forces remodel the developing heart's #extracellularmatrix. Image & research by Alessandra Gentile & @MargaAlbu et al @StainierLab @mpi_hlr @GunawanLab @wwu_muenster in @Dev_journal. On bpod.org.uk/archive/2024/7/2…
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Eric Pollitt retweeted
4 Jul 2024
Llgl1 mediates timely epicardial emergence and establishment of an apical laminin sheath around the trabeculating cardiac ventricle
Read this Research Article by Eric Pollitt @StaphEric, Emily Noël @noelresearchlab and colleagues @ScienceShef:
journals.biologists.com/dev/…
ALT Figure 1 A-J: Llgl1 promotes organised trabeculation and ventricular wall integrity. (A-J) Live light-sheet z-slices through the ventricle of Tg(myl7:LifeAct-GFP) transgenic wild-type and llgl1 mutant embryos visualising the myocardium at 120 hpf (A-E) and 80 hpf (F-J). Scale bars: 50 μm. Wild-type embryos have regular trabeculae emerging predominantly from the outer curvature of the ventricular wall at 120 hpf (A), whereas llgl1 mutant embryos exhibit disorganised trabeculae, ranging from wild-type-like (B), through to irregular trabecular CMs and multilayering of CMs (C-E). Some llgl1 mutants at 120 hpf exhibit apically extruding CMs (arrow, E). At 80 hpf in llgl1 mutants, CMs extrude apically from multiple locations in the ventricular wall (arrows G-J).
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1 Jul 2024
Llgl1 mediates timely epicardial emergence and establishment of an apical laminin sheath around the trabeculating cardiac ventricle - our new paper in @Dev_journal is out now! journals.biologists.com/dev/… @noelresearchlab @deputy_derrick @J_SanchezPosada
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Eric Pollitt retweeted
27 Mar 2024
ICYMI
26 Mar 2024
1/8 Are you interested in knocking genes out in adult zebrafish? If so, you should read our new preprint! Our new ~ubiquitous ubbR:CreERT2 driver enables gene knockout in adult #zebrafish hearts with efficiency approaching 100%. Yes, we quantified it. biorxiv.org/content/10.1101/…
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Eric Pollitt retweeted
21 Feb 2024
We hope that many of its features can be utilised to understand morphology beyond the walls of the developing heart - so take it for a whirl, and let us know how you get on.
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Eric Pollitt retweeted
21 Feb 2024
The preprint describing the software, and how we used it to analyse zebrafish heart morphogenesis, are on bioRxiv tinyurl.com/mvjd45ze, while morphoHeart itself is available on GitHub github.com/jsanchez679/morph…
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Eric Pollitt retweeted
21 Feb 2024
morphoHeart is live! @J_SanchezPosada developed software for 3D visualisation and morphometric analysis of the heart including negative space segmentation of cardiac ECM volume. All packaged up into a handy GUI. #morphometrics #zebrafish
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Eric Pollitt retweeted
11 Jan 2024
A wee 2024 reminder that I'm looking for a job. Ideally it would be in the UK or Ireland (Scotland would be the dream). Please give me a heads-up if you have an opening coming up or know someone who has. You can check out my interests & CV at rosssmcinnes.github.io/ Cheers! 😃
14 Nov 2023
My time at Birmingham will very sadly be ending in March. If you're looking for a dashingly handsome, well-spoken postdoc, that's not me, but I can do wet and dry lab ([functional]genomics, metagenomics, RNAseq) work in Gram-positives (especially Enterococcus) so keep me in mind.
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Eric Pollitt retweeted
17 Jul 2023
A real paradigm shift from Astrid Hendriks and @N_van_sorge on how to understand adaptive immunity to S. aureus
IgM (not IgG) to wall teichoic acids predicts protection vs mortality in bacteremia—IgM superior in promoting opsonophagocytosis, including as a monoclonal therapeutic
17 Jul 2023
Did you ever wonder about the role of IgM in host defense against Staphylococcus aureus?
In this preprint, we identify opsonic IgM to be critical for human immunity to S. aureus. Potential implications for antibody-based therapies and vaccines. biorxiv.org/content/10.1101/…
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Eric Pollitt retweeted
16 Jul 2023
Star Wars immunization promotional poster, 1979
ALT A photo of C3PO and R2D2, with the caption "Parents of Earth, are your children fully immunized?"
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Eric Pollitt retweeted
13 Apr 2023
One more #AskZebrafish 🤔 from Slack: What are the best antibodies for labeling zebrafish vasculature? We are talking antibodies and not transgenics 🙏
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Fantastic work by Dr Ryan Snodgrass and many colleagues.
13 Apr 2023
Brand new article from @timchico
& co from @sheffielduni on vascular abnormalities in #zebrafish model of haemorrhagic #telangiectasia that were prevented by synergistic inhibition of MEK & mTOR pathways, suggesting potential novel therapeutic approach
📰journals.biologists.com/dmm/…
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Eric Pollitt retweeted
15 Mar 2023
The method used to prepare Mycobacterium tuberculosis cells affects the bacterial cell wall, changing infection outcomes. elifesciences.org/articles/8…
ALT Blue, red and yellow epifluorescence microscopy image
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