📢 New SOC for MIBC
#ESMO25 Dr. Christof Vulsteke presents KEYNOTE-905:
🚫 No cisplatin? No problem. EV pembro delivers.
👥 n=344 cis-ineligible MIBC (80% renal impairment, 15% ECOG 2)
🔹 EFS HR 0.40 | OS HR 0.50
🔹 pCR: 57.1% vs 8.6% (ITT, non-op = non-responders)
🔹 No ↑ surgical complications
✅ 1st phase 3 trial showing OS benefit in this population| Unprecedented pCR↑
@urotoday @myESMO