Apoptosis and mitochondria lab based at @LivUni. We do lots of western blots and immunofluorescence! #phdlife #apoptosis #mitochondria

Joined April 2019
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Varadarajan Lab retweeted
Really sad to hear of the passing of Beth Levine today. It is a huge loss to the autophagy community where she was a pioneer in the field. Our thoughts are with her family at this tough time.
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Another one leaves the nest, with Dr. @GYedida successfully defending his PhD thesis yesterday πŸŽ‰πŸŽˆπŸΎ! One might think @VaradarajanLab spends more time designing πŸŽ‚ than doing πŸ‘¨β€πŸ”¬ πŸ‘©β€πŸ”¬ ! @LivUni @livuniITM @NWCRCentre
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Congratulations and many thanks to @rachelcarter44 and all others involved in this work! @VaradarajanLab @livHeadandNeck
BH3 mimetics as a potential therapy for head & neck cancer: Targeting BCL-XL & MCL-1 induces apoptosis in patient tissue explants & tumour shrinkage in a zebrafish xenograft model. nature.com/articles/s41419-0… @VaradarajanLab @livHeadandNeck
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Many Congratulations Dr Aoula Agooby Emad Al-Zebeeby!!! Thanks @VignirsLab & @Pseudoenzyme for being great examiners! Special thanks to @drclairesworld for your unwavering support! #phdlife #PhD #viva #proudPI @VaradarajanLab @LivUni @livuniITM
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Varadarajan Lab retweeted
Successful Viva @LivUni today - great work from @VaradarajanLab πŸ§¬πŸ”¬
Collaboration at it's best. Dinner in #liverpool with @VaradarajanLab @VignirsLab @VignirHelgason #Viva #PhD
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Varadarajan Lab retweeted
Collaboration at it's best. Dinner in #liverpool with @VaradarajanLab @VignirsLab @VignirHelgason #Viva #PhD
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Varadarajan Lab retweeted
On #WorldCancerResearchDay we acknowledge the passion and dedication of our #cancer scientists here @livuni @livuniITM @NWCRCentre @livuniIIB @srochaliv @KaliraiHelen @SarahCoupland3 @VaradarajanLab @livuninews
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Varadarajan Lab retweeted
19 Sep 2019
Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies cell.com/cancer-cell/fulltex…

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Varadarajan Lab retweeted
4 Sep 2019
DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis ncbi.nlm.nih.gov/pmc/article…
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Varadarajan Lab retweeted
12 Jul 2019
Acquiring images of 3D solid spheroids can be challenging. Download our tech note to see a comparison of different optical clearing strategies for 3D spheroids, and quantification of their effectiveness and impact on spheroid morphology. ms.spr.ly/6017TzcvD
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Mateus is now PhinisheD! Congratulations Dr. Milani! πŸ₯ƒπŸΊπŸ»πŸΉπŸ₯‚πŸ·πŸΈ@VaradarajanLab @milanim @LivUni @livuniITM #phdchat #phd #viva #research #mitochondria #apoptosis #CancerResearch
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Varadarajan Lab retweeted
Apogossypol-mediated reorganisation of the endoplasmic reticulum antagonises mitochondrial fission and apoptosis nature.com/articles/s41419-0…
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Varadarajan Lab retweeted
From: Cell Death Differentiation The good, the bad and the autophagosome: exploring unanswered questions of autophagy-dependent cell death nature.com/articles/s41418-0…
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Varadarajan Lab retweeted
Researchers from the First Affiliated Hospital, Bengbu Medical College in China report Nf1 loss associated with #Kras driven #LungAdenocarcinoma, that depend on increased glutaminolysis --> therapeutic inhibition of glutaminase or Psat1 #openacess: bit.ly/2IXtHk3
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Varadarajan Lab retweeted
A @ScienceTM study discovered how #teriflunomide, an FDA-approved treatment for #MultipleSclerosis, selectively targeted hyperactive #TCells in 50 patients enrolled in a phase 3b clinical trial. fcld.ly/98zpe94 #MS #Health
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Varadarajan Lab retweeted
In a recent study published in @NatureComms, Jefferson researchers showed that a gene called gasdermin E, which is downregulated in many cancers, aids cells in dying in an unexpected way, & may also suppress tumor growth: bit.ly/2PtTrFg #JeffersonResearch @JeffersonUniv
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Varadarajan Lab retweeted
Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection @trendscancer #ASGCT19 bit.ly/2V3LjkX bit.ly/2V3LjkX

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Varadarajan Lab retweeted
Access your free #CellPress Selection: Resistance in #CancerTherapy sponsored by @officialatcc. bit.ly/2LcXfMG
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Varadarajan Lab retweeted
29 Apr 2019
From: Cell Death Differentiation BFL1 modulates apoptosis at the membrane level through a bifunctional and multimodal mechanism showing key differences with BCLXL nature.com/articles/s41418-0…
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