Biophysical and structural studies of ligand-gated ion channels. Lipid modulation. @WUSTL_AnesRsrch Washington University Department of Anesthesiology
Joined August 2020
- Tweets 242
- Following 431
- Followers 620
- Likes 1,317
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Pinned Tweet
2 Jan 2024
Our study on nanodiscs and ion channel structure is now published: rdcu.be/duXkK. We hope this will spur more consideration into the impact of nanodiscs on membrane protein structure.
@VikramDalal_37 @PageAnesthesia @GraceBrannigan @WUSTL_AnesRsrch
2 Jan 2024
This is a very interesting paper showing that nanodiscs, typically used to preserve lipids for structural analysis of membrane proteins, can affect the structure of the target protein.
First paper I read this year, happy 2024!
nature.com/articles/s41467-0…
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Wayland Cheng Lab retweeted
8 Oct 2025
Structural mechanism of lipid modulation of pentameric ligand-gated ion channel activity biorxiv.org/content/10.1101/… #biorxiv_biophys
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Wayland Cheng Lab retweeted
22 Sep 2024
Another paper from my postdoc with @CrinaNimigean on lipid modulation of an ion channel is out now. Great effort by @thon_oli further showcasing the value of a great model system. Congrats to the entire team!
nature.com/articles/s41467-0…
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Wayland Cheng Lab retweeted
6 Sep 2024
I liked the reaction on the soundtrack/musical synopsis for our last paper, maybe every paper should have one. If you haven't seen/heard it yet, weekend is coming !
Paper @embojournal embopress.org/doi/full/10.10…
Soundtrack by me and byteBBY @BebeByte
on.soundcloud.com/sMNHNNSSdb…
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Wayland Cheng Lab retweeted
21 Aug 2024
Join our team at Case Western Reserve University!
#CWRUSOM #cryoEM #Ionchannels
nature.com/naturecareers/job…
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Wayland Cheng Lab retweeted
19 Jun 2024
Structures of channels in Open conformation are rare. Thrilled to share our latest manuscript..
Structural basis for hyperpolarization-dependent opening of human HCN1 channel disq.us/t/4p78xec
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Wayland Cheng Lab retweeted
18 Mar 2024
A postdoc position is available in our lab to study how ion channels communicate with one another. Cryo-EM, electrophysiology, protein biophysics. A great opportunity for structural biologists to learn electrophysiology methods or vice versa.
vanpetegemlab.com/opportunit…
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Wayland Cheng Lab retweeted
13 Feb 2024
Celebrating another year of successful collaboration with the @WChengLab at the Dandelion. Looking forward to seeing you in LA for #BPS2025!
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Wayland Cheng Lab retweeted
8 Jan 2024
These simulations of membrane proteins in nanodiscs were so fun. Thank you @WChengLab for your continued enthusiasm for simulations that go beyond the basics - we are lucky computational collaborators! @VikramDalal_37 @PageAnesthesia
2 Jan 2024
Our study on nanodiscs and ion channel structure is now published: rdcu.be/duXkK. We hope this will spur more consideration into the impact of nanodiscs on membrane protein structure.
@VikramDalal_37 @PageAnesthesia @GraceBrannigan @WUSTL_AnesRsrch
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Wayland Cheng Lab retweeted
2 Jan 2024
It's my pleasure to share that I have been awarded an AHA postdoctoral fellowship. I would like to acknowledge my mentor @WChengLab for unimaginable support, referres: @Pravindrak_IITR, @ShaillyTomar and Alex Evers, and @American_Heart for belief in my proposal.
@WChengLab
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Wayland Cheng Lab retweeted
2 Jan 2024
This is a very interesting paper showing that nanodiscs, typically used to preserve lipids for structural analysis of membrane proteins, can affect the structure of the target protein.
First paper I read this year, happy 2024!
nature.com/articles/s41467-0…
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Wayland Cheng Lab retweeted
13 Nov 2023
🥁Presenting a #namd protocol for SAFEP, the surprisingly straight-forward approach to FEP.
Easy to follow tutorial? ✅
Extensive troubleshooting guide? ✅
This project with @jerome_henin 's groups was years in the making! Now at @livecomsj
tinyurl.com/yezhr73h
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Wayland Cheng Lab retweeted
26 Oct 2023
It’ll be great to have a new postdoc in my group to lead a new project (biochem/biophys/ephys). If there’s anyone out there who wants to chat, message me. I might be a little weird, but the proteins we’re interested in are weirder!
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Wayland Cheng Lab retweeted
📢Please RT📢
CIMED is looking to recruit a new tenure-track faculty member doing cryo-EM analyses of membrane proteins. For new or established faculty, and departmental affiliation in Anesthesiology, Biochemistry or Cell Biology, this is a fantastic opportunity! @WUSTL
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Wayland Cheng Lab retweeted
10 Jun 2023
We’re hiring! Projects combine genomics, in vivo ephys and synaptic physiology to understand how plasticity in basal ganglia circuits give rise to maladaptive decision making- with a focus on models of substance use disorder and chronic pain! (1/n)
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Wayland Cheng Lab retweeted
1 Jun 2023
Announcing FAER’s approved Spring 2023 Grantees! Join us in congratulating these outstanding physician-investigators & read more on our website!
asahq.org/faer/about/news-an…
#Anesthesiology #Research #TheFutureIsFAER #FAERgrantees #FAERgrants @AndreaJIbarra
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Wayland Cheng Lab retweeted
5 May 2023
3 postdocs landing dream jobs, 1 PhD student graduating means: A)I'm so proud of these amazing scientists and happy for their success & B) We have opportunities to recruit new colleagues!
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Wayland Cheng Lab retweeted
26 Feb 2023
Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1 dlvr.it/Sk1M8M
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Wayland Cheng Lab retweeted
3 Mar 2023
We are looking for a new postdoc to join our group. There are several MS-based research opportunities in our group, including membrane proteins, viral proteins, and amyloid-forming proteins. If interested, please see the link below
wustl.wd1.myworkdayjobs.com/…
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Wayland Cheng Lab retweeted
3 Mar 2023
Please check out new work from my lab, published this week in @NatureComms. Great collaborative work with my @NIGMS K08 mentor @CrinaNimigean and my anesthesiologist/biophysicist buddy @WChengLab. rdcu.be/c6lKa
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